| molecular evidence that the range of the vancouver island outbreak of cryptococcus gattii infection has expanded into the pacific northwest in the united states. | cryptococcus neoformans frequently causes fungal meningitis in immunocompromised patients, whereas the related species c. gattii is restricted to tropical and subtropical regions,where it usually infects immunocompetent individuals.an outbreak of c. gattii infection that began in 1999 on vancouver island has resulted in endemic c. gattii infection and caused numerous human and veterinary infections; the outbreak's range has spread to mainland british columbia. the outbreak-related isolates have ... | 2009 | 19220140 |
| mitochondrial dna inheritance in the human fungal pathogen cryptococcus gattii. | the inheritance of mitochondrial dna (mtdna) is predominantly uniparental in most sexual eukaryotes. in this study, we examined the mitochondrial inheritance pattern of cryptococcus gattii, a basidiomycetous yeast responsible for the recent and ongoing outbreak of cryptococcal infections in the us pacific northwest and british columbia (especially vancouver island) in canada. using molecular markers, we analyzed the inheritance of mtdna in 14 crosses between strains within and between divergent ... | 2015 | 25577978 |
| pitfalls in serological diagnosis of cryptococcus gattii infections. | the detection of cryptococcal antigen by latex agglutination tests (lats), enzyme-linked immunoassays (elisa), or lateral flow assay (lfa) is an important tool for diagnosis of a cryptococcus infection. cerebrospinal fluid and/or serum samples of 10 patients with cryptococcosis due to cryptococcus gattii or a hybrid of cryptococcus neoformans and c. gattii were examined by three lats (the immy latex-crypto(®) test, the pastorex(tm) crypto plus, and the remel cryptococcus antigen test kit) and th ... | 2015 | 26337090 |
| spread of cryptococcus gattii into pacific northwest region of the united states. | cryptococcus gattii has emerged as a human and animal pathogen in the pacific northwest. first recognized on vancouver island, british columbia, canada, it now involves mainland british columbia, and washington and oregon in the united states. in canada, the incidence of disease has been one of the highest worldwide. in the united states, lack of cryptococcal species identification and case surveillance limit our knowledge of c. gattii epidemiology. infections in the pacific northwest are caused ... | 2009 | 19757550 |
| cryptococcus gattii isolates from the british columbia cryptococcosis outbreak induce less protective inflammation in a murine model of infection than cryptococcus neoformans. | the fungal pathogen cryptococcus neoformans causes approximately one million cases of cryptococcosis per year in people with aids. in contrast, the related species c. gattii is responsible for a much smaller number of cases, but these often occur in immunocompetent people. in fact, c. gattii has emerged in the last decade as the frequent cause of cryptococcosis in otherwise healthy people in british columbia. we analyzed the immune responses elicited by three c. gattii strains and one c. neoform ... | 2009 | 19635827 |
| characterization of environmental sources of the human and animal pathogen cryptococcus gattii in british columbia, canada, and the pacific northwest of the united states. | cryptococcus gattii has recently emerged as a primary pathogen of humans and wild and domesticated animals in british columbia, particularly on vancouver island. c. gattii infections are typically infections of the pulmonary and/or the central nervous system, and the incidence of infection in british columbia is currently the highest reported globally. prior to this emergence, the environmental distribution of and the extent of colonization by c. gattii in british columbia were unknown. we chara ... | 2007 | 17194837 |
| cryptococcus neoformans infections at vancouver hospital and health sciences centre (1997-2002): epidemiology, microbiology and histopathology. | an outbreak of infections due to a rare subspecies of cryptococcus neoformans (var. gattii) was recognized on vancouver island (vi), british columbia, in 2002, which had affected 59, mostly immunocompetent, individuals since 1999. the objectives of this study were to: (1) determine if the outbreak had spread to vancouver and its surrounding communities and (2) review the epidemiological, clinical and pathological features of all cryptococcal infections in patients admitted to the vancouver hospi ... | 2004 | 15314203 |
| cryptococcosis in ferrets: a diverse spectrum of clinical disease. | cryptococcosis was diagnosed in seven ferrets (five from australia; two from western canada) displaying a wide range of clinical signs. two of the ferrets lived together. one (5-years-old) had cryptococcal rhinitis and presented when the infection spread to the nasal bridge. its sibling developed cryptococcal abscessation of the right retropharyngeal lymph node 12 months later, soon after developing a severe skin condition. dna fingerprinting and microsatellite analysis demonstrated that the two ... | 2002 | 12537139 |
| british columbia. canine cryptococcus neoformans. | | 1997 | 9360794 |
| current status of cryptococcosis in canada. | the concurrent use of microscopic, cultural, histopathologic and immunologic procedures enabled us to diagnose 91 cases of cryptococcosis, belonging to cutaneous, pulmonary, meningeal and disseminated types, from the time this mycosis was first reported in canada in 1953 to the present. these cases occurred predominantly in quebec (43%) followed by alberta, british columbia, ontario, saskatchewan, manitoba, new brunswick and newfoundland. it is not known whether any cryptococcus neoformans infec ... | 1990 | 2352543 |
| clinicopathologic features of an unusual outbreak of cryptococcosis in dogs, cats, ferrets, and a bird: 38 cases (january to july 2003). | to determine clinical and pathologic findings associated with an outbreak of cryptococcosis in an unusual geographic location (british columbia, canada). | 2004 | 15626222 |
| multispecies outbreak of cryptococcosis on southern vancouver island, british columbia. | | 2002 | 12395765 |
| [australian fungus makes canada unsafe]. | | 2002 | 12389579 |