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molecular typing and antifungal susceptibility of clinical and environmental cryptococcus neoformans species complex isolates in goiania, brazil.a total of 124 cryptococcus isolates, including 84 clinical strains obtained from cerebrospinal fluid from aids patients and 40 environmental isolates from pigeon excreta and from eucalyptus trees, were studied. the varieties, serotypes, phospholipase activity and molecular profile of these isolates were determined. cryptococcus neoformans var. grubii serotype a was identified in 120 isolates and cryptococcus gattii serotype b in four isolates. the clinical isolates showed higher phospholipase a ...201019500261
antifungal susceptibilities of clinical and environmental isolates of cryptococcus neoformans in goiânia city, goiás, brazil.we evaluated the antifungal activities of amphotericin b, fluconazole, itraconazole and voriconazole in 70 cryptococcus neoformans strains obtained from cerebrospinal fluid from aids patients and 40 c. neoformans strains isolated from the environment. four clinical isolates were identified as c. neoformans var. gattii. the susceptibility test was done using a broth microdilution method according to nccls m27-a2. range minimal inhibitory concentrations (mics) for c. neoformans clinical isolates w ...200516302107
characterization of cryptococcus neoformans isolated from urban environmental sources in goiânia, goiás state, brazil.cryptococcus neoformans is an opportunistic fungal pathogen that causes meningoencephalitis as the most frequent clinical presentation in immunocompromised patients, mainly in people infected by hiv. this fungus is an environmental encapsulated yeast, commonly found in soil enriched with avian droppings and plant material. a total of 290 samples of pigeon and the other avian droppings, soil, ornamental trees and vegetable material associated with eucalyptus trees were collected to study environm ...200516138201
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