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recovery of angiostrongylus cantonensis from cerebrospinal fluid of a child with eosinophilic meningitis.viable angiostrongylus cantonensis was recovered from the cerebrospinal fluid of a 17-month-old boy with eosinophilic meningitis. neurological findings were minimal, and the child had an uneventful recovery.1979479360
experimental infection of pacific island mollusks with angiostrongylus cantonensis. 19695764195
molecular differentiation and phylogenetic relationships of three angiostrongylus species and angiostrongylus cantonensis geographical isolates based on a 66-kda protein gene of a. cantonensis (nematoda: angiostrongylidae).the phylogenetic relationships and molecular differentiation of three species of angiostrongylid nematodes (angiostrongylus cantonensis, angiostrongylus costaricensis and angiostrongylus malaysiensis) were studied using the ac primers for a 66-kda protein gene of a. cantonensis. the ac primers successfully amplified the genomic dna of these angiostrongylid nematodes. no amplification was detected for the dna of ascaris lumbricoides, ascaris suum, anisakis simplex, gnathostoma spinigerum, toxocar ...201020566366
clinical manifestations of eosinophilic memingitis due to angiostrongylus cantonensis.between 1959 and 1976, 34 patients were seen in hawaii with eosinophilic meningitis. angiostrongylus cantonensis was recovered from two of these patients. the remaining cases were presumed to be due to this parasite because of clinical and epidemiologic findings. the most likely source of infection for eight patients was ingesting raw terrestrial snails or slugs, and for six patients eating raw or poorly cooked crustaceans. patients typically presented with severe headache; neck stiffness and fe ...1979574219
eosinophilic meningitis/angiostrongyliasis from eating aquaculture-raised snails: a case report. 19989844300
studies on eosinophilic meningitis. 3. epidemiologic and clinical observations on pacific islands and the possible etiologic role of angiostrongylus cantonensis. 19676066788
studies on eosinophilic meningitis. v. molluscan hosts of angiostrongylus cantonensis on pacific islands. 19695777734
geographic distribution of angiostrongylus cantonensis in wild rats (rattus rattus) and terrestrial snails in florida, usa.the parasitic nematode angiostrongylus cantonensis is a major cause of eosinophilic meningitis in humans, and has been documented in other incidental hosts such as birds, horses, dogs and non-human primates. it is endemic in hawaii, and there have been sporadic reports in the southern continental united states. this parasite uses rats as definitive hosts and snails as intermediate hosts. in this study, we collected potential definitive and intermediate hosts throughout florida to ascertain the g ...201728542310
quantitative pcr estimates angiostrongylus cantonensis (rat lungworm) infection levels in semi-slugs (parmarion martensi).the life cycle of the nematode angiostrongylus cantonensis involves rats as the definitive host and slugs and snails as intermediate hosts. humans can become infected upon ingestion of intermediate or paratenic (passive carrier) hosts containing stage l3 a. cantonensis larvae. here, we report a quantitative pcr (qpcr) assay that provides a reliable, relative measure of parasite load in intermediate hosts. quantification of the levels of infection of intermediate hosts is critical for determining ...201222902292
diverse gastropod hosts of angiostrongylus cantonensis, the rat lungworm, globally and with a focus on the hawaiian islands.eosinophilic meningitis caused by the parasitic nematode angiostrongylus cantonensis is an emerging infectious disease with recent outbreaks primarily in tropical and subtropical locations around the world, including hawaii. humans contract the disease primarily through ingestion of infected gastropods, the intermediate hosts of angiostrongylus cantonensis. effective prevention of the disease and control of the spread of the parasite require a thorough understanding of the parasite's hosts, incl ...201424788772
the potential danger of eating wild lettuce: a brief review of human rat lungworm infection.angiostrongylus cantonensis, the causative agent of human rat lungworm disease, is the most common cause of eosinophilic meningitis worldwide and is endemic throughout asia pacific. it is acquired through the consumption of infected freshwater mollusks or contaminated produce. human angiostrongyliasis is usually a self-limited disease presenting with headache and various neurologic sequelae varying from cranial nerve palsies to radiculitis and/or paresthesias. fatal cases are rare, and manifest ...201425478300
angiostrongylus cantonensis in introduced gastropods in southern florida.angiostrongylus cantonensis , the rat lungworm, is a zoonotic, parasitic nematode that uses the rat as a definitive host and gastropods as intermediate hosts. it is prevalent in parts of asia, the pacific islands, and the caribbean. in the united states, a. cantonensis is established in hawaii and in recent years has been reported in alabama, california, louisiana, and florida, where it has been found in the reintroduced lissachatina fulica (also known as achatina fulica), the giant african snai ...201525564891
molecular phylogeography of angiostrongylus cantonensis (nematoda: angiostrongylidae) and genetic relationships with congeners using cytochrome b gene marker.angiostrongylus cantonensis is an important emerging zoonotic parasite causing human eosinophilic meningitis (or meningoencephalitis) in many parts of the world. to-date there is only a single study using mitochondrial cytochrome b (cytb) gene to determine its genetic structure in eight geographical localities in thailand. the present study examined the molecular phylogeography of this rat lungworm and its phylogenetic relationship with congeners using cytb gene marker. a total of 15 cytb haplot ...201525930187
eosinophilic meningitis attributable to angiostrongylus cantonensis infection in hawaii: clinical characteristics and potential exposures.the most common infectious cause of eosinophilic meningitis is angiostrongylus cantonensis, which is transmitted largely by consumption of snails/slugs. we previously identified cases of angiostrongyliasis that occurred in hawaii from 2001 to 2005; the highest incidence was on the island of hawaii. we now report symptoms, laboratory parameters, and exposures. eighteen patients were evaluated; 94% had headache, and 65% had sensory symptoms (paresthesia, hyperesthesia, and/or numbness). these symp ...201121976573
molecular differentiation of angiostrongylus taxa (nematoda: angiostrongylidae) by cytochrome c oxidase subunit i (coi) gene sequences.nematodes of the genus angiostrongylus are parasites of rodents and carnivores. they reside in the pulmonary or mesenteric arteries of their hosts. two species are pathogenic in humans -angiostrongylus cantonensis causes eosinophilic meningitis or meningoencephalitis, and angiostrongylus costaricensis produces abdominal angiostrongyliasis. in addition angiostrongylus malaysiensis may have the potential of being pathogenic in humans. the mitochondrial gene cytochrome c oxidase subunit i (coi) of ...201020654571
meiotic chromosomes and sex determination mechanism in thailand and hawaii isolates of angiostrongylus cantonensis (nematoda: angiostrongylidae).angiostrongylus cantonensis, the nematode lungworm of rats, has a xx/x0 sex-determination mechanism. the chromosome constitution consists of 10 autosomes, with 2n=12, xx in the female and 2n=11, x0 in the male. meiosis-i shows five bivalents and one univalent for the male worm, and six bivalents for the female worm. the chromosome constitution of the thailand and hawaii isolates of a. cantonensis is similar to those reported for the taxa from japan, egypt and mainland china.200920237450
distribution of eosinophilic meningitis cases attributable to angiostrongylus cantonensis, hawaii.during november 2004-january 2005, 5 cases of eosinophilic meningitis (em) attributable to angiostrongylus cantonensis infection were reported in hawaii. to determine if this temporal clustering reflected an increased incidence, we ascertained em and a. cantonensis cases by systematic review of statewide laboratory and medical records for january 2001-february 2005 and generalized the data to population estimates. we identified 83 em cases; 24 (29%) were attributed to a. cantonensis infection, w ...200718217550
eosinophilic meningitis? consider angiostrongyliasis. 200616895272
polymorphic and sex-limited phosphoglucomutase in parastrongylus cantonensis (nematoda: angiostrongylidae).phosphoglucomutase was studied by polyacrylamide gel electrophoresis in the thailand and hawaii isolates of parastrongylus cantonensis (also known as angiostrongylus cantonensis). two loci were present. the faster-moving locus (pgm-1) was polymorphic in the hawaii isolate, represented by two alleles - the faster-moving, less common pgm-1a and the slower-moving, more common pgm-1b . it was monomorphic for the faster-moving allele pgm-1a in the thailand isolate. the slower-moving locus (pgm-2) was ...200516883277
studies on eosinophilic meningitis. i. observations on the geographic distribution of angiostrongylus cantonensis in the pacific area and its prevalence in wild rats. 196514246081
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