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acquired immune deficiency syndrome (aids) in brazil. necropsy findings.according to the 15 autopsies performed at the department of pathological anatomy, escola paulista de medicina, são paulo, brazil, it was confirmed that acquired immunodeficiency syndrome (aids) occurs preferably in young homosexual males, who die in a short period of time of the disease, which leads to a consumptive state verified by cachexia of the cadavers. the most affected organs of this series were the lungs and encephalum, exactly the ones responsible for the immediate cause of death. in ...19873620018
human herpesvirus 8 group b and c variants circulating in são paulo, brazil. 19989535001
detection of hhv-8 in reactive lymphoid tissue of patients from são paulo state, brazil. 200211825934
searching for antibodies to hhv-8 in children born to hiv-1 infected mothers from são paulo, brazil: relationship to maternal infection.with the spread of aids, many hiv-1 infected women and children have been diagnosed with kaposi's sarcoma (ks), mostly in africa. since the discovery of the causative agent of ks (human herpesvirus 8, hhv-8) several seroepidemiological studies have been conducted to identify groups at risk of ks. the present study was conducted in order to add some information from são paulo, brazil. we searched for hhv-8 antibodies in plasma samples obtained from a cohort of 108 children born to hiv-1 infected ...200312929889
human herpesvirus-8 (hhv-8) antibodies in women from são paulo, brazil. association with behavioral factors and kaposi's sarcoma.with the spread of aids, many hiv-infected women have been diagnosed with kaposi's sarcoma (ks), especially in africa. since the discovery of a novel herpesvirus as the causative agent of ks (human herpesvirus 8 - hhv-8) several seroepidemiological studies have been conducted to identify groups at risk for ks. the risk for women in brazil has not been studied.200314636479
prevalence of antibodies to human herpesvirus-8 in populations with and without risk for infection in são paulo state.human herpesvirus 8 (hhv-8) is a newly described herpesvirus that is etiologically associated with all forms of kaposi's sarcoma (ks). seroepidemiological studies have shown high prevalence rates of hhv-8 antibodies among men who have sex with men (msm) and aids patients, african children, brazilian amerindians, and elderly individuals in certain regions of europe. the aim of the present study was to determine the prevalence of hhv-8 antibodies in healthy children and young adults from different ...200414689053
seroprevalence of human herpesvirus-8 in blood donors from different geographical regions of argentina, brazil, and chile.human herpesvirus-8 (hhv-8) causes kaposi's sarcoma (ks) and lymphoproliferative disorders in both hiv-infected and uninfected patients. hhv-8 has a worldwide occurrence but infection rates vary according to a combination of geographic and behavioral risks. the main transmission route seems to be sexual, nevertheless, nasal secretions, saliva, blood, and organ graft have been proposed. hhv-8 was postulated as a new infectious agent for screening in blood donors. the aim of this study was to eval ...200414981770
epidemiology of kaposi's sarcoma in patients with acquired immunodeficiency syndrome in são paulo, brazil.kaposi's sarcoma (ks) is the most frequent neoplasm in patients with acquired immunodeficiency syndrome (aids). although many studies on ks epidemiology have been performed in other countries, few have been carried out in brazil despite the high incidence of aids.200415357742
human herpesvirus 8 (hhv-8) infection in hiv/aids patients from santos, brazil: seroprevalence and associated factors.the goal of this study was to evaluate the seroprevalence of human herpesvirus 8 (hhv-8) infection among hiv-infected individuals from brazil and the associated risk factors.200515614122
seroprevalence of human herpesvirus 8 infection in children born to hiv-1-infected women in são paulo, brazil.human herpesvirus-8 (hhv-8) appears to be transmitted mainly by sexual contact. however, several studies suggest that in developing countries the infection may be acquired early in life by routes other than sexual transmission. the present study estimated the seroprevalence of hhv-8 in brazilian children born to hiv-1-infected mothers. the serum samples were collected in a cross-sectional cohort study from 99 children born to hiv-infected mothers (median age 3.27 years; range 1.5-13.8 years) att ...200515785835
molecular characterization of kaposi's sarcoma associated herpesvirus (kshv) from patients with aids-associated kaposi's sarcoma in sao paulo, brazil.kaposi's sarcoma (ks) is caused by kaposi's sarcoma associated herpesvirus (kshv/hhv-8), the eighth herpesvirus found to infect humans. the molecular epidemiology of kshv is related closely to ethnicity and geographical location of studied populations. there is little epidemiological and molecular information about kshv strains circulating in brazil.200515797365
comparative study of kaposi's sarcoma-associated herpesvirus serological assays using clinically and serologically defined reference standards and latent class analysis.accurate determination of infection with kaposi's sarcoma-associated herpesvirus (kshv) has been hindered by the lack of a "gold standard" for comparison of serological assays used to estimate kshv prevalence in serosurveys conducted in different settings. we have evaluated the performance of five in-house (developed at university college london [ucl], united kingdom, and at the virology laboratory of the instituto de medicine tropical [imt] in sao paulo, brazil) and two commercial (abi and diav ...200717182752
human herpesvirus-8 infection in hemodialysis patients from são paulo, brazil: preliminary results.epidemiological studies conducted in endemic areas of human herpesvirus 8 (hhv-8) infection have shown iatrogenic kaposi's sarcoma in renal transplant recipients. hemodialysis has not yet been demonstrated to be a route of virus transmission/acquisition, although recently blood transfusion has been suggested as a vehicle of hhv-8 transmission. the present study searching hhv-8 antibodies among serum samples from 70 hemodialysis patients disclosed a high prevalence of infection (22.9%). there was ...200718089318
prevalence of, and risk factors for kaposi's sarcoma-associated herpesvirus infection among blood donors in brazil: a multi-center serosurvey.kaposi's sarcoma-associated herpesvirus (kshv) is endemic in the amazon and rare in southern regions of brazil. however, geographical distribution and epidemiological correlates of infection in this large country are still poorly defined. to estimate the seroprevalence of, and risk factors for, kshv infection in brazil, a multi-center study was conducted among 3,493 first-time voluntary unpaid blood donors from salvador, sao paulo and manaus. antibodies against kshv were detected using a whole-v ...200818461622
high human herpesvirus 8 (hhv-8) prevalence, clinical correlates and high incidence among recently hiv-1-infected subjects in sao paulo, brazil.background: human herpesvirus 8 (hhv-8) is the etiological agent for kaposi sarcoma, which occurs especially in hiv-infected subjects. hhv-8 infection and its clinical correlates have not been well characterized in recently hiv-1-infected subjects, especially men who have sex with men (msm). methodology/ principal findings: we assessed the hhv-8 seroprevalence, clinical correlates, and incidence after one year of follow-up in a cohort of 228 recently hiv-1-infected individuals, of whom 83.6% wer ...200919479040
Non-detection of human herpesvirus 8 (HHV-8) DNA in HHV-8-seropositive blood donors from three Brazilian regions.Human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV), is the etiologic agent of all forms of Kaposi's sarcoma, primary effusion lymphoma and the plasmablastic cell variant of multicentric Castleman disease. In endemic areas of sub-Saharan Africa, blood transfusions have been associated with a substantial risk of HHV-8 transmission. By contrast, several studies among healthy blood donors from North America have failed to detect HHV-8 DNA in samples of seroposi ...201121858163
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