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reduced seroprevalence of kaposi's sarcoma-associated herpesvirus (kshv), human herpesvirus 8 (hhv8), related to suppression of anopheles density in italy.in two formerly malarious parts of italy, age-related seroprevalence rates of kaposi's sarcoma-associated herpesvirus [human herpesvirus 8 (kshv/hhv8)] were determined from local blood donors and correlated with periods of vector control during anti-malaria campaigns. in veneto, decreased kshv/hhv8 seroprevalence in the 1951-1955 birth cohort coincides with the peak of ddt house-spraying. in sardinia, where larviciding augmented indoor ddt-spraying, a significant drop of kshv/hhv8 seroprevalence ...200314651663
the bloodsucking arthropod bite as possible cofactor in the transmission of human herpesvirus-8 infection and in the expression of kaposi's sarcoma disease.based on a review of the literature on human herpesvirus-8 (hhv8) and kaposi's sarcoma (ks) and on the distribution of ks in italy (veneto region particularly), we hypothesize that the bite of bloodsucking arthropods is a cofactor in the seroconversion to hhv8 positivity and probably in the pathogenesis of ks. the bloodsucking arthropod releases with saliva powerful antihaemostatics and immunomodulators which may favour the replication and the establishment of the pathogen. transmission would de ...200212404820
seroprevalence of kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 in several regions of italy.to study the seroprevalence of kaposi's sarcoma-associated herpesvirus/human herpesvirus type 8 (kshv/hhv-8) in 779 italian blood donors.199810195244
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