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abundance of pseudallescheria/scedosporium species in the australian urban environment suggests a possible source for scedosporiosis including the colonization of airways in cystic fibrosis.members of the pseudallescheria/scedosporium species complex are emerging opportunistic fungal pathogens which have the capacity to colonize patients with damaged airways, including those with cystic fibrosis (cf). assuming human infection is acquired via inhalation of fungal spores from the environment, we performed a qualitative environmental survey encompassing 25 urban, semirural and rural sites in the greater sydney region to determine the prevalence of pseudallescheria/scedosporium species ...201021067333
clinical associations and prevalence of scedosporium spp. in australian cystic fibrosis patients: identification of novel risk factors?risk factors for the association of scedosporium in cases of cystic fibrosis (cf) and its clinical implications are poorly understood. clinical, lung function and laboratory data of adult cf patients in sydney (april 2008-march 2009) were prospectively analysed for such risk factors. expectorated sputa were cultured for bacteria and examined for fungi using standard mycological and scedosporium-selective media, and by an internal transcribed spacer region-targeted multiplex pcr assay. scedospori ...201021067328
population-based surveillance for scedosporiosis in australia: epidemiology, disease manifestations and emergence of scedosporium aurantiacum infection.australia-wide population-based surveillance for scedosporiosis identified 180 cases, with 118 (65.6%) cases of colonization and 62 (34.4%) cases of infection. predisposing factors for isolation of scedosporium spp. included chronic lung disease in 37.8% and malignancy in 21.7% of cases. predictors of invasive disease (n=62) included haematological stem cell transplantation (n=7), leukaemia (n=16) and diabetes mellitus (n=8). of 183 phenotypically-speciated isolates, 75 (41%) were scedosporium p ...200919549223
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