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evaluation of chemical and antiviral properties of essential oils from south american plants.the essential oils of seven aromatic plants from córdoba, san luis and san juan provinces (argentina) were isolated by steam distillation and analysed by a gas chromatography/mass spectrometry technique. the oils were screened for cytotoxicity and in vitro inhibitory activity against herpes simplex virus type 1 (hsv-1), dengue virus type 2 (denv-2) and junin virus (junv) by a virucidal test. the oils showed a variable virucidal action according to the virus. the better relationship between cytot ...200516130522
[present status of zoonotic hemorrhagic fevers of south america].since 1958, the geographical distribution of argentine hemorrhagic fever (ahf) has especially extended non only into the province of buenos aires but also towards the provinces of santa fe and cordoba, leading to an estimated population at risk of about 1.2 m inhabitants. recent epidemiological field studies has confirmed the major role of calomys musculinus and c. laucha rodents in both transmission to man and conservation of junin virus in nature. however, the human infection may result essent ...19937819800
[laboratory evidence of the activity of junin virus in the southeast of cordoba: hypothesis on its epidemiology]. 196414144586
microgeographic distribution of allele frequencies in populations of calomys laucha (rodentia, cricetidae).the microgeographic differentiation of allelic frequencies was analysed in two population samples of calomys laucha, collected in a grid set in cultivated fields at laguna larga (córdoba province, argentina). one of the samples (n = 79) was obtained in may (autumn), when the population density is at a maximum, and the other (n = 85) in november (spring), at the onset of reproductive activity. fst values for the november sample show significant differences between the six groups over which the sa ...19911880049
junin virus activity in two rural populations of the argentine hemorrhagic fever (ahf) endemic area.to determine the prevalence of inapparent infection with junin virus among the rural population and its relation to the clinical disease, a serological study was carried out in two zones of the endemic area of argentine hemorrhagic fever (ahf). from the first appearance of ahf in the zones (1963) and the moment of the survey (1977), 14 years had passed. a total of 695 serum samples were obtained, 540 from córdoba and 155 from buenos aires. of the 695 serum samples, 83 were positive for neutraliz ...19836317799
genetic diversity of the junin virus in argentina: geographic and temporal patterns.rna was purified from 39 strains of cell-cultured junin virus (jun) from central argentina, which included both human- and rodent-derived isolates (a total of 26 and 13, respectively), as well as from 2 laboratory jun strains, xj cl3 and xj #44. jun-specific primers were used to amplify a 511-nucleotide (nt) fragment of the nucleocapsid protein gene and a 495-nt fragment of the glycoprotein 1 (gp1) gene. genetic diversity among jun strains studied was up to 13% at the nt level and up to 9% at th ...200010873755
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