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early onset neonatal group b streptococcus (gbs) infection: associated obstetric risk factors.an analysis of all early onset neonatal group b streptococcal (gbs) infections at the royal women's hospital, melbourne was made for the 10-year period 1979-1988. there were 104 cases with 29 neonatal deaths (28%). one or more predisposing perinatal risk factors was evident in 82% of cases (premature labour 79%, prolonged membrane rupture (greater than 12 hours) 57%, premature rupture of the membranes 69%, maternal sepsis 29%). overall, 88% of gbs infections were evident within 24 hours of birth ...19911930030
group b streptococcus (gbs) and neonatal infections: the case for intrapartum chemoprophylaxis.at the royal women's hospital, melbourne over an 8-year period (1981-1988) all public antenatal patients were screened at 32 weeks' gestation for group b streptococcus (gbs). in a total of 30,197 livebirths there were no early onset neonatal gbs infections in infants of treated asymptomatic carrier mothers. by contrast there were 27 infections with 8 deaths in an unscreened control group of private patients (total livebirths 26,915). it is recommended that gbs screening occur antenatally at 28 w ...19911930031
perinatal mortality in victoria, australia: role of group b streptococcus.group b beta-hemolytic streptococcus is the most common infective cause of neonatal morbidity and mortality. it is therefore surprising that no agreement exists for an approach to its prevention. there is also increasing evidence that occult infection may play an etiologic role in premature rupture of the membranes and preterm labor. in this report we review the role of group b beta-hemolytic streptococcal sepsis as a cause of perinatal wastage in the state of victoria, australia during the peri ...19902240114
early-onset neonatal group b streptococcal sepsis: economics of various prevention strategies.to evaluate three strategies for preventing group b streptococcal neonatal sepsis in large teaching hospitals and to examine their cost effectiveness and cost benefit.19957746174
restriction endonuclease analysis of group b streptococcal isolates from two distinct geographical regions.this study examined isolates of group b streptococci (gbs) by latex seroagglutination and restriction endonuclease analysis (rea). rea analysis was performed with high- and low-frequency cutting enzymes, and fragments were resolved by linear and pulsed-field gel electrophoresis (pfge), respectively. gbs isolates were derived from a regional acute-care hospital and a tertiary referral obstetric hospital. the most common serotype isolated at the general hospital was serotype v (42%). a high incide ...19968864940
prevention of perinatal group b streptococcal disease: screening practice in public hospitals in victoria.to survey clinical protocols for prevention of early-onset group b streptococcal disease (eogbsd) of the newborn in public maternity hospitals.200010844917
is penicillin and/or erythromycin resistance present in clinical isolates of group b streptococcus in our community?traditionally group b streptococcus (gbs) has not exhibited resistance to the antibiotics penicillin and erythromycin. recently there are reports from north america whereby some gbs isolates have exhibited resistance to erythromycin. there have been no studies reported to date to determine whether this resistance trend is also occurring in the australian population. over a period of six months from january to june 1999, 250 gbs isolates were collected at the royal women's hospital, melbourne. se ...200212495105
compliance with a risk factor-based intrapartum prophylaxis program for neonatal group b streptococcal disease.the us centre for disease control (cdc) recently amended their guidelines for the prevention of early-onset group b streptococcal disease (eogbsd) of the newborn to recommend bacteriological screening, rather than risk factor-based screening, as the preferred method of identifying 'at risk' mother-infant pairs. this recommendation was derived from population data suggesting that the effectiveness of bacteriological screening was superior to a risk-factor approach because antibiotic compliance wa ...200616704472
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