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[a study on beta-hemolytic streptococci isolated from the throats of healthy school children in taiwan: changing patterns of type distribution and drug sesceptibility (author's transl)]. 1978101620
antibacterial activity of cefepime in vitro.cefepime is a new parenterally active fourth-generation cephalosporin which is undergoing in vitro and in vivo evaluations. using the standard agar dilution method we compared the in vitro activity of this drug with other cephalosporins and ciprofloxacin against clinical isolates of escherichia coli (98 strains), klebsiella pneumoniae (99 strains), acinetobacter spp. (24 strains), pseudomonas aeruginosa (98 strains), haemophilus influenzae (108 strains), staphylococcus aureus (100 strains), ente ...19947842821
clinical characteristics and antimicrobial susceptibility of invasive group b streptococcal infections in nonpregnant adults in taiwan.to understand group b streptococcal infections other than peripartum events in adults and to provide a regional antimicrobial therapy guide, we conducted a retrospective analysis of invasive diseases caused by group b streptococcus (gbs) in 33 nonpregnant adults treated in a medical center in southern taiwan, from january 1993 to july 1994. antimicrobial susceptibility tests were performed using the agar dilution method. the incidence of the disease was 1.6 per 1,000 nonpregnant adult admissions ...19979290273
group b streptococcal infections in children: the changing spectrum of infections in infants.during a 9-year period from january 1988 to december 1996, 36 patients less than 18 years of age with lancefield group b streptococcal infections were seen in the national cheng kung university hospital. among 33 infants with invasive group b streptococcal infections, 3 (9%) were early onset disease (eod), 27 (82%) late onset disease (lod) and 3 (9%) onset beyond the third month of life. all cases of eod were detected during the first day of life and 2 of them were premature births. in the infan ...199810596988
group b streptococcal infection in neonates: an 11-year review.group b streptococcal (gbs) infection is an important cause of infant morbidity and mortality. the purpose of this study is to evaluate the incidence, clinical characteristics, mortality and complications of this infection. from 1985 through 1995, 66 infants with early onset disease (eod) and 23 infants with late onset disease (lod) were treated at mackay memorial hospital (mmh). the occurrence rate of eod was 3.26-10.08/1000 admissions. the incidence of the disease was 0.11-1.39/1000 live birth ...199910910592
serotyping and antimicrobial susceptibility of group b streptococcus over an eight-year period in southern taiwan.the increase in penicillin resistance among pneumococci and viridans streptococci and the development of serotype-specific conjugate vaccine have increased the need for knowledge of the antimicrobial susceptibility and the capsular serotypes of group b streptococci. over an 8-year period, 351 group b streptococcal isolates from southern taiwan were tested for antimicrobial susceptibility and serotype determination. eighty-seven percent of the isolates were typeable. types iii (28.5%) and v (27.1 ...200111453594
high incidence of erythromycin resistance among clinical isolates of streptococcus agalactiae in taiwan.the in vitro susceptibilities of 266 isolates of streptococcus agalactiae determined by the agar dilution method showed that 6% of isolates were nonsusceptible to penicillin and 46% was resistant to erythromycin. of the erythromycin-resistant isolates, 86.3% had the macrolide-lincosamide-streptogramin (mls) resistance phenotype (constitutive mls, 85.5%; inducible mls, 0.8%) and 13.7% had the m phenotype.200111600380
neonatal group b streptococcus infection in taiwan: an increasing trend. 200212632782
group b streptococcal infections in children in a tertiary care hospital in southern taiwan.group b streptococcus (gbs) is widely recognized as a leading cause of neonatal sepsis and meningitis. recently, gbs infections in older children have been increasingly noted. this retrospective study investigated the clinical features, distribution of serotypes, and antimicrobial susceptibility of gbs isolates in a tertiary care center in southern taiwan over a 12-year period. gbs isolates recovered from various infected sites in 54 children treated from june 1991 through december 2002 were stu ...200415221037
neonatal group b streptococcal infection: a 7-year experience.this retrospective study was designed to determine the trend of neonatal group b streptococcal (gbs) infection during the past 7 years at the chang gung memorial hospital of kaohsiung, as well as to assess the risk factors, clinical features and patient outcomes.200415508872
polyclonal spread of erythromycin-resistant streptococcus agalactiae in southern taiwan.resistance to erythromycin is common among streptococcus agalactiae in taiwan, however the genetic relatedness of erythromycin-resistant isolates has not yet been reported. from 1991 to 2001, 629 clinical isolates of s. agalactiae were collected in a medical center at tainan in southern taiwan, of which 189 (30.0%) were resistant to erythromycin. the isolation rate of erythromycin-resistant group b streptococcus (gbs) was stable, irrespective of the clinical sources or study period. among them, ...200415650375
clinical characteristics of group b streptococcus bacteremia in non-pregnant adults.group b streptococcus (gbs) [streptococcus agalactiae] is an emerging cause of disease in non-pregnant adults with underlying diseases. this retrospective study analyzed 90 episodes of gbs bacteremia in adults occurring over a 4-year period.200617066202
risk factors for recurrence of group b streptococcus colonization in a subsequent pregnancy.to document rates of recurrent group b streptococci (gbs) colonization in women with previous gbs colonization in an initial pregnancy and to assess maternal risk factors associated with recurrence.200818310374
the antimicrobial activity of heyneanol a extracted from the root of taiwanese wild grape.to search for antimicrobial compounds against pathogenic bacteria from grape vines (vitis spp.). to investigate the antimicrobial efficacy of active compounds towards methicillin-resistant staphylococcus aureus (mrsa).200818312569
the prevalence of erythromycin resistance in group b streptococcal isolates at a university hospital in taiwan.due to reduced antibiotic consumption in taiwan, erythromycin resistance rate had decreased in streptococcus pyogenes, but it increased in streptococcus pneumoniae. the objectives of the present study were (1) to determine the erythromycin and clindamycin resistance rate and minimum inhibitory concentration (mic) of the group b streptococcus (gbs) clinical isolates, and (2) to investigate the mechanism responsible for the macrolide, lincosamide, and group b streptogramin (mls(b)) resistance. a t ...200819025386
epidemiology of and prenatal molecular distinction between invasive and colonizing group b streptococci in the netherlands and taiwan.the identification of markers for virulent group b streptococci (gbs) could guide prenatal prevention and intervention strategies. we compared the distribution of serotypes and potential pathogenicity islands (ppis) between invasive and colonizing gbs. colonizing and invasive strains from the netherlands and taiwan were serotyped. we used polymerase chain reaction (pcr) for the amplification of several new ppi markers. several combinations of ppi-specific markers and serotypes were associated wi ...200919333631
the changing face of early-onset neonatal sepsis after the implementation of a maternal group b streptococcus screening and intrapartum prophylaxis policy--a study in one medical center.early-onset sepsis (eos) is the major cause of neonatal morbidity and mortality. maternal group b streptococcus (gbs) screening and intrapartum antibiotic prophylaxis (iap) were implemented in our hospital in 2004. our aim was to evaluate the effectiveness of the program and changes in pathogens and antibiotic susceptibility.201121524627
multilocus sequence typing of invasive group b streptococcus in central area of taiwan.background: group b streptococcus (gbs) (streptococcus agalactiae) is an important pathogen in neonates, pregnant women, and adults with underlying disease. methods: fifty clinical isolates were collected during the period 2001-2004 and analyzed by multilocus sequence typing and capsular serotyping. results: the six major sequence types (sts) identified by multilocus sequence typing were st1, st12, st19, st17, st23, and st10. five major clonal complexes (ccs) and one single st (st61) from 11 dif ...201121697020
group b streptococcal infection in taiwan: maternal colonization and neonatal infection.there is no national data on group b streptococcus (gbs) infection in taiwan. we investigated incidence of maternal gbs colonization and neonatal gbs infection rate and clinical pictures of neonatal gbs infection to estimate the value of intrapartum chemoprophylactic strategy in taiwan.201121835363
in vitro activities of tedizolid and linezolid against gram-positive cocci associated with acute bacterial skin and skin structure infections and pneumonia.tedizolid is a novel, expanded-spectrum oxazolidinone with potent activity against a wide range of gram-positive pathogens. a total of 425 isolates of gram-positive bacteria were obtained consecutively from patients with acute bacterial skin and skin structure infections (absssis) or pneumonia. these isolates included methicillin-susceptible staphylococcus aureus (mssa) (n = 100), methicillin-resistant staphylococcus aureus (mrsa) (n = 100), streptococcus pyogenes (n = 50), streptococcus agalact ...201526248355
genetic and pathogenic difference between streptococcus agalactiae serotype ia fish and human isolates.streptococcus agalactiae (gbs) is a common pathogen to infect newborn, woman, the elderly, and immuno-compromised human and fish. 37 fish isolates and 554 human isolates of the gbs in 2007-2012 were investigated in serotypes, antibiotic susceptibility, genetic difference and pathogenicity to tilapia.201627484120
high prevalence of streptococcus agalactiae from vaginas of women in taiwan and its mechanisms of macrolide and quinolone resistance.streptococcus agalactiae (gbs), is the most common pathogen causing infections among perinatal women and neonatal babies. nonetheless, there are few studies on the occurrence of gbs among the pregnant women and the mechanisms of gbs resistance to quinolones and macrolides in taiwan.201524767417
serotype distribution and resistance genes associated with macrolide and fluoroquinolone resistance in streptococcus agalactiae isolates from a hospital in southern taiwan.antimicrobial resistance of streptococcus agalactiae (group b streptococcus, gbs) has been emerging worldwide. we aimed to examine the correlation of drug-resistant genes with serotypes and with the mutations of the quinolone resistance-determining region (qrdr) in gbs isolates.201625179723
maternal anxiety about prenatal screening for group b streptococcus disease and impact of positive colonization results.universal screening for colonization by group b streptococcus (gbs) is the recommended strategy to reduce incidence of colonization in newborns and prevent neonatal gbs-related disease. this study was designed to assess maternal anxiety levels about prenatal screening and psychological impact of positive colonization test results.200616513247
genetically diverse serotypes iii and vi substitute major clonal disseminated serotypes ib and v as prevalent serotypes of streptococcus agalactiae from 2007 to 2012.streptococcus agalactiae [group b streptococcus (gbs)] has become more prevalent in nonpregnant women, the elderly, and people who are immunocompromised. we investigated the serotype and genomic changes of gbs human isolates from different hospitals from 2007 to 2012.201626316010
emergence of fluoroquinolone resistance in group b streptococcal isolates in taiwan.of 1,994 group b streptococcal isolates collected, 26 (1.3%) of the isolates were resistant to levofloxacin, and cross-resistance to other fluoroquinolones was observed. the emergence and prevalence of high-level fluoroquinolone resistance in genetically unrelated isolates were linked to the presence of gyra, parc, and pare triple mutations in each isolate.200818299411
group b streptococcal disease in nonpregnant patients: emergence of highly resistant strains of serotype ib in taiwan in 2006 to 2008.among the 228 group b streptococcus (gbs) isolates recovered in 2006 to 2008, higher resistance to erythromycin (58.3%) and clindamycin (57.9%) was found in isolates with certain resistance phenotypes. serotype ib isolates (24.6%) were the second most prevalent serotype, next to serotype v (29.4%), and showed the highest resistance rates to erythromycin (91.0%) and clindamycin (82.1%).201020444969
group b streptococcal soft tissue infections in non-pregnant adults.skin and soft tissue infections are the most common presentations of invasive streptococcus agalactiae infections. this study reviewed 71 patients in a medical centre in southern taiwan with s. agalactiae soft tissue infections. the mortality rate was 7%, and 11% of patients lost their extremities following extensive tissue necrosis. critical illness and the presence of cutaneous ulceration heralded a fatal prognosis. risk-factors for amputation of limbs included advanced age, cutaneous ulcerati ...200515966977
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