identification and distribution of new world leishmania species characterized by serodeme analysis using monoclonal antibodies.five hundred thirty stocks of leishmania isolated from human and domestic and wild reservoir hosts, representing a wide geographic distribution of endemic foci of american cutaneous (acl) and visceral leishmaniases (avl) were characterized and identified at species and/or subspecies levels based on their reactivity to a cross-panel of specific monoclonal antibodies using a radioimmune binding assay. this study confirms and extends our preliminary results on the high specificity of some of these ...19873826486
[disseminated cutaneous leishmaniasis due to leishmania viannia braziliensis in the state of maranhão, brazil].the authors describe a case of a patient from barreirinhas, ma with disseminated cutaneous leishmaniasis, who presented 58 lesions spread all over his body, with many different aspects, but ulcerative lesions were predominant. they discuss the difficulty of laboratory diagnosis in the beginning of the investigation and its therapeutics implications. the parasite isolated was identified as leishmania viannia braziliensis using monoclonal antibodies in the fluorescent antibody test. this form of t ...19938128071
expression of foxp3, tgf-β and il-10 in american cutaneous leishmaniasis lesions.regulatory t cells (tregs) are a unique population of cd25+cd4+ t cells that regulate innate and adaptive immune responses and have the ability to control the excessive or misdirected effects of the immune system. this modulation involves different mechanisms, such as the suppression of t cell proliferation and cytokine production, the secretion of suppressive cytokines (il-10 and tgf-β) and the induction of effector t cell apoptosis in humans with infectious diseases such as leishmania infectio ...201423922083
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