Publications

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multicentre investigation of pathogenic bacteria and antibiotic resistance genes in chinese patients with acute exacerbation of chronic obstructive pulmonary disease.a prospective observational study to investigate the distribution and antimicrobial resistance of pathogenic bacteria in patients with acute exacerbation of chronic obstructive pulmonary disease (aecopd) in beijing, china.201526152913
point-prevalence survey of healthcare-associated infections in beijing, china: a survey and analysis in 2014.point-prevalence studies can identify priorities for infection control.201627140419
molecular epidemiology of bla oxa-23 -producing carbapenem-resistant acinetobacter baumannii in a single institution over a 65-month period in north china.carbapenem-resistant acinetobacter baumannii poses a significant threat to hospitalized patients, as few therapeutic options remain. thus, we investigated the molecular epidemiology and mechanism of resistance of carbapenem-resistant a.baumannii isolates in beijing, china.201728056839
a bronchofiberoscopy-associated outbreak of multidrug-resistant acinetobacter baumannii in an intensive care unit in beijing, china.bronchofiberscopy, a widely used procedure for the diagnosis of various pulmonary diseases within intensive care units, has a history of association with nosocomial infections. between september and november 2009, an outbreak caused by multidrug-resistant acinetobacter baumannii (mdr-ab) was observed in the intensive care unit of a tertiary care hospital in beijing, china. this study is aimed to describe the course and control of this outbreak and investigate the related risk factors.201223198973
[vicissitude of antibiotic sensitivity of gram negative bacilli in patients with infection in emergency departments in beijing during 2005 to 2007].to investigate changes in antibiotic sensitivity of gram negative bacilli infections among emergency patients in large hospitals in beijing during 2005 to 2007.200920042141
susceptibility patterns and molecular epidemiology of multidrug-resistant acinetobacter baumannii strains from three military hospitals in china.to date, little has been reported on the susceptibility patterns and molecular characterisation of multidrug-resistant acinetobacter baumannii (mdrab) clinical isolates from different chinese military hospitals. in this study, 49 mdrab strains were collected from three military hospitals during 2007. the minimum inhibitory concentrations (mics) of 13 antibiotics were determined for each strain. genotyping and dendrogram analysis of mdrab strains were performed using the repetitive sequence-based ...201020036519
antibiotic resistance patterns of gram-negative and gram-positive strains isolated from inpatients with nosocomial infections in a tertiary hospital in beijing, china from 2011 to 2014.this study was to evaluate the resistance of antimicrobial agents against pathogens from inpatients with nosocomial infection collected in beijing, china, during 2011-2014. measurement of minimum inhibitory concentrations (mics) was carried out using the broth microdilution method with the clinical and laboratory standards institute (clsi) guidelines as the indicator. a total of 5442 gram-negative and 806 gram-positive isolates were collected in this study in 2011-2014. two carbapenem-resistant ...201627347770
higher isolation of ndm-1 producing acinetobacter baumannii from the sewage of the hospitals in beijing.multidrug resistant microbes present in the environment are a potential public health risk. in this study, we investigate the presence of new delhi metallo-β-lactamase 1 (ndm-1) producing bacteria in the 99 water samples in beijing city, including river water, treated drinking water, raw water samples from the pools and sewage from 4 comprehensive hospitals. for the bla ndm-1 positive isolate, antimicrobial susceptibility testing was further analyzed, and pulsed field gel electrophoresis (pfge) ...201323755152
spread of imipenem-resistant acinetobacter baumannii of european clone ii in western china.the aim of this study was to investigate the distribution of resistance genes and the clonal relationship amongst imipenem-resistant acinetobacter baumannii isolates from ten hospitals in western china as well as to compare the molecular epidemiological data with those of isolates from two hospitals in hangzhou and beijing. genes encoding oxa carbapenemases, metallo-+¦-lactamases, ampc cephalosporinase and carbapenem resistance-associated outer membrane protein (caro) were screened using polymer ...201121705198
antimicrobial susceptibility patterns of clinical isolates of gram-negative bacteria obtained from intensive care units in a tertiary hospital in beijing, china.in this study we investigated the prevalence of antimicrobial resistance in clinical isolates of gram-negative bacteria obtained from intensive care units (icus) in the people's liberation army (pla) 309 hospital located in beijing, china. between 2007 and 2010, a total of 1949 isolates of gram-negative bacteria were collected and tested using an antibiotic susceptibility assay. a marked decrease was observed in the susceptibility of acinetobacter baumannii to imipenem and amikacin as compared t ...201121803697
impact of reclaimed water irrigation on antibiotic resistance in public parks, beijing, china.the abundance and distribution of antibiotics and antibiotic resistance genes (args) in soils from six parks using reclaimed water in beijing, china, were characterized. three classes of commonly used antibiotics (tetracycles, quinolones, and sulfonamides) were analyzed by liquid chromatography-tandem mass spectrometry (lc-ms/ms). the highest concentrations of tetracyclines and quinolones were 145.2 μg kg(-1) and 79.2 μg kg(-1), respectively. detected tetg, tetw, suli, and sulii genes were quant ...201424071635
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