Publications

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epidemiology of visceral leishmaniasis in india.kala-azar has re-emerged from near eradication. the annual estimate for the incidence and prevalence of kala-azar cases worldwide is 0.5 million and 2.5 million, respectively. of these, 90% of the confirmed cases occur in india, nepal, bangladesh and sudan. in india, it is a serious problem in bihar, west bengal and eastern uttar pradesh where there is under-reporting of kala-azar and post kala-azar dermal leishmaniasis in women and children 0-9 years of age. untreated cases of kala-azar are ass ...199910416321
influence of topography on the endemicity of kala-azar: a study based on remote sensing and geographical information system.kala-azar, a fatal infectious disease in many indian states, particularly in bihar, west bengal, uttar pradesh, and jharkhand, is caused by the protozoan parasite leishmania donovani and transmitted by the sandfly vector phlebotomus argentipes. the vector is distributed all over the country but the disease is confined to particular zones since before the last century. in this study, parameters such as altitude, temperature, humidity, rainfall and the normalized difference vegetation index (ndvi) ...201020503185
kala-azar in uttar pradesh--a study of 66 patients.sixty-six laboratory confirmed cases of kala-azar from uttar pradesh attending various hospitals of delhi over a period of 10 years (1989-1999) have been analysed. the geographical distribution showed that the disease involved widespread areas varying from a height of 10,000 ft. extending up-to the plains. male, female ratio was 2:1 and maximum patients were in the age group of 5-15 years. l.d. bodies could be demonstrated in 59 patients in bone marrow aspirate smears while in 7 in splenic aspir ...200212718341
clinico-epidemiological profiles of post-kala-azar dermal leishmaniasis in varanasi.twenty-seven cases of post kala-azar dermal leishmaniasis (p. k. d. l.) were detected in an endemic focus of kala-azar in sujabad village in varanasi distt. male-female ratio of cases was 4.4:1. majority (66.6 per cent) of cases had macular lesions. histopathology of one case showed leishmania donovani (l. d.) bodies. densities of sand fly were more in pockets where p. k. d. l. cases were detected. all the 13 cases, which were treated with sodium antimony gluconate, responded well to therapy.19892614049
enzyme-linked immunosorbent assay in the diagnosis of kala-azar in bhadohi (varanasi), india.an enzyme-linked immunosorbent assay (elisa) developed using leishmania donovani promastigote soluble antigen gave positive responses in practically all the clinically and parasitologically diagnosed patients with kala-azar in a preliminary study. healthy control subjects from non-endemic and endemic areas gave negative results. no cross-reaction was observed with patients having leprosy, filariasis, malaria, tuberculosis, or amoebiasis. blood samples collected on filter paper were adequate for ...19902260170
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