| [the reactivity of sera from hemorrhagic fever in patients with renal syndromes to the recombination nucleotide proteins from european hantaviruses in hubei province]. | five yeast-expressed recombination nucleotide proteins of european hantaviruses were prepared as coated antigens to detect hantavirus-specific antibodies in sera from hemorrhagic fever with renal syndromes (hfrs) in hubei province, through elisa assay. the relativity among hantaviruses prevailing in different areas was investigated. | 2008 | 19040041 |
| [association of hemorrhagic fever with renal syndrome and hla-drb allele polymorphisms in han nationality, hubei province.]. | to understand the association of human leukocyte antigen (hla)-drb polymorphism and patients diagnosed as hemorrhagic fever with renal syndrome (hfrs). | 2009 | 20193583 |
| Genetic analysis of hantaviruses and their rodent hosts in central-south China. | Hantaan virus (HTNV) and Seoul virus (SEOV) are two major zoonotic pathogens of hemorrhagic fever with renal syndrome (HFRS) in Asia. Hubei province, which is located in the central-south China, had been one of the most severe epidemic areas of HFRS. To investigate phylogenetic relationships, genetic diversity and geographic distribution of HTNV and SEOV in their reservoir hosts, a total of 687 rodents were trapped in this area between 2000 and 2009. Sequences of partial S- and M-segments of han ... | 2011 | 22108583 |
| serological characterization of a hantavirus from hubei, china. | hantavirus hv114, isolated from urine of a patient during epidemic of hemorrhagic fever with renal syndrome (hfrs) in china, was subjected to a detailed serological characterization using enzyme-linked immunosorbent assay (elisa), neutralization test and indirect immunofluorescence antibody assay (ifa). it has been found that hv114 is antigenically similar to the hantavirus a9 strain isolated in china and to the hantaan 76-118 virus (htnv 76-118), but different from the hantaviruses isolated fro ... | 2004 | 15230468 |
| [serotyping of hemorrhagic fever with renal syndrome in hubei province]. | ninety-two serum specimens, positive for antibodies against hemorrhagic fever with renal syndrome (hfrs) virus in initial screening with immunofluorescence assay technic (ifat), were serotyped with micro cell pathogenic effects neutralization test based on preliminary epidemiological classification of epidemic foci of hfrs throughout the province to find out serological evidence of hfrs typing in hubei province. it was found that 48 of the specimens were belonged to type i (htn) accounting for 5 ... | 1997 | 9812603 |
| specific humoral reaction of hemorrhagic fever with renal syndrome (hfrs) patients in china to recombinant nucleocapsid proteins from european hantaviruses. | hemorrhagic fever with renal syndrome (hfrs) is endemic in east asia and europe. this study was initiated to investigate the reactivity of antibodies in sera of chinese hfrs patients with the recombinant nucleocapsid proteins (rnps) of hantaan virus (htnv), dobrava-belgrade virus (dobv), and puumala virus (puuv), which are the prevalent hantavirus strains in europe. forty-eight pairs of acute and convalescent sera were collected from hfrs patients in hubei, china (1985-2002) and tested by indire ... | 2011 | 21222012 |
| variability of g1 gene of hantaviruses occurring in the hubei province, p.r. china from 1985 to 2000. | we studied variability of g1 gene of hantaviruses occurring in the hubei province, p.r. china. serum samples were collected from 229 patients with hemorrhagic fever with renal syndromes (hfrs) during 1985--1989 and 1996--2000 and were tested by rt-pcr for the presence of hantaan and seoul viruses (htnvs, seovs) and by restriction fragment length polymorphism (rflp) analysis for the respective pattern. out of 229 sera 166 (72.5%) were hantavirus-positive by rt-pcr, including 124 from 1985--1989 a ... | 2005 | 15929399 |
| genetic characterization of a new subtype of hantaan virus isolated from a hemorrhagic fever with renal syndrome (hfrs) epidemic area in hubei province, china. | to characterize hantaviruses currently circulating in the hemorrhagic fever with renal syndrome (hfrs) epidemic area of hubei province, rodents were captured and serum samples were collected from several hfrs patients. the partial s segment of the hantaviruses amplified from two serum samples had a high degree of sequence identity to the corresponding hantavirus strain isolated from apodemus agrarius (designated as hv004). the complete s, m, and l segment sequences of hv004 were determined. the ... | 2012 | 22718221 |
| dynamics of hantavirus infections in humans and animals in wuhan city, hubei, china. | hemorrhagic fever with renal syndrome (hfrs) has been a significant public problem since the first cases were reported in 1961 in wuhan city (capital of hubei province of china). epidemiological surveys were carried out to better understand the dynamics of hantavirus infection in humans and animals in wuhan. during 1961-2011, a total of 21,820 hfrs cases were registered in wuhan. the two large epidemics had occurred during 1970-1991. they reached peaks in 1973 and 1983, respectively. there have ... | 2012 | 22910184 |
| influence of hla-drb alleles on haemorrhagic fever with renal syndrome in a chinese han population in hubei province, china. | specific human leucocyte antigen (hla) alleles are considered a genetic risk factor for the progression of haemorrhagic fever with renal syndrome (hfrs) caused by hantaviruses. the aim of this study was to establish whether hla-drb alleles are associated with the severity of hfrs caused by different types of hantaviruses in a chinese han population from hubei province of central china. twenty-two specific hla-drb alleles were analysed by sequence-specific primer-polymerase chain reaction (ssp-pc ... | 2015 | 25169964 |