| survival of cystic fibrosis patients in south australia. evidence that cystic fibrosis centre care leads to better survival. | life tables were calculated for 205 south australians with cystic fibrosis. an improvement in survival was noted between 1948 and 1982. ninety-three per cent of patients who were diagnosed as having cystic fibrosis after 1973 were alive at 14 years of age, compared with 40% of those who were diagnosed between 1948 and 1973. a cystic fibrosis clinic was established in 1973 and much of this improvement is attributed to the care provided by this centre. deaths from meconium ileus fell from 58% of i ... | 1985 | 4033505 |
| lysogenic conversion in pseudomonas aeruginosa. | holloway, b. w. (university of melbourne, victoria, australia) and g. n. cooper. lysogenic conversion in pseudomonas aeruginosa. j. bacteriol. 84:1321-1324. 1962.-when pseudomonas aeruginosa strain 1 is lysogenized with phage d3, it loses the ability to adsorb this phage. this loss is attributed to an alteration of the somatic antigens of the bacterium, initially detected by differences in the opsonizing capacity of normal mouse serum for the lysogenic and nonlysogenic strains. antigenic analysi ... | 1962 | 13961373 |
| clinical profile of adult cystic fibrosis patients with frequent epidemic clones of pseudomonas aeruginosa. | earlier reports suggested that pseudomonas aeruginosa frequent epidemic clones circulating in cystic fibrosis (cf) centres had increased virulence. however, recent data show no consistent associations with virulence, and suggest attenuation of virulence in chronic infection. changes to infection control programmes in relation to frequent epidemic clones should be based on their frequency, virulence across all age groups and mode of acquisition. the australian epidemic strain-1 (aes-1) (or the me ... | 2010 | 20573059 |
| the microbiology and outcome of sepsis in victoria, australia. | we analysed data from 33741 patients with icd-10-am-defined sepsis from an australian hospital morbidity dataset to investigate the relationships between specific types of organisms, potential risk factors for infection, organ dysfunction, icu utilization and hospital mortality. a total of 24% of patients received some of their care in an intensive care unit, and the overall hospital mortality rate was 18%. gram-positive bacteria were isolated in 27% of cases and gram-negative bacteria in 20%. s ... | 2006 | 16490135 |
| rapid genotyping of pseudomonas aeruginosa isolates harboured by adult and paediatric patients with cystic fibrosis using repetitive-element-based pcr assays. | in this study, the suitability of two repetitive-element-based pcr (rep-pcr) assays, enterobacterial repetitive intergenic consensus (eric)-pcr and box-pcr, to rapidly characterize pseudomonas aeruginosa strains isolated from patients with cystic fibrosis (cf) was examined. eric-pcr utilizes paired sequence-specific primers and box-pcr a single primer that target highly conserved repetitive elements in the p. aeruginosa genome. using these rep-pcr assays, 163 p. aeruginosa isolates cultured from ... | 2004 | 15496385 |
| detection of a widespread clone of pseudomonas aeruginosa in a pediatric cystic fibrosis clinic. | cross-infection by pseudomonas aeruginosa between unrelated patients with cystic fibrosis (cf) is believed to be uncommon. after detecting a genotypically identical strain of p. aeruginosa in five unrelated children with cf dying from severe lung disease, we determined its prevalence within a large cf clinic using pulsed-field gel electrophoresis and random amplified polymorphic dna assays. the clinical status of p. aeruginosa-infected patients was also determined. between september and december ... | 2002 | 12359658 |