| incidence and level of exotoxin a in proteolytic cell-free cultures of clinical isolates of pseudomonas aeruginosa collected from hospitals in riyadh, saudi arabia. | mice lethality bioassay revealed that out of 102 proteolytic cell-free cultures of pseudomonas aeruginosa only 17 (15%) were lethal with values of 19-48 ld50/ml. antitoxin a antiserum neutralized the lethality providing evidence that the main lethal compound in the cell free cultures was exotoxin a. the neutralization also ruled out the lethal contribution of protease, elastase and phospholipase c. the presence of exotoxin a in a proteolytic environment may indicate less efficient proteolytic ac ... | 1992 | 1435349 |
| antibiotic sensitivity pattern; experience at university hospital, riyadh, saudi arabia. | results of sensitivity testing were discussed based on examination of 5192 isolates of the various bacteria isolated from clinical specimens from king khalid university hospital in riyadh, saudi arabia. streptococcus pyogenes and streptococcus pneumoniae were sensitive to penicillin and erythromycin. the sensitivity pattern of staphylococcus aureus was also predictable as they were fairly sensitive to both methicillin (98%) and erythromycin (96%). neisseria gonorrhoeae (27%) showed a high level ... | 1991 | 1960392 |
| saudi arabian-american differences in antimicrobial resistance of escherichia, klebsiella, and pseudomonas. | increasing microbial resistance to newly developed antibiotics has been a limiting factor in the therapeutic use of these agents. to determine the extent of the problem, in vitro antimicrobial susceptibility of 7,140 clinical isolates of escherichia coli, klebsiella pneumoniae, and pseudomonas aeruginosa to seven commonly used antibiotics was established at the 1,700-bed riyadh central hospital in saudi arabia and compared with 5,513 isolates at the oklahoma memorial hospital and veterans admini ... | 1989 | 2509721 |
| mechanisms of gentamicin resistance in gram-negative bacilli in riyadh, kingdom of saudi arabia. | a survey was undertaken of the prevalence and mechanisms of gentamicin resistance in gram-negative bacilli in riyadh. gentamicin resistance, as assessed by the stokes method, occurred in less than 2% of isolates of escherichia coli, about 10-25% of most other enterobacteria, about 40% of acinetobacter spp. and about 25% of pseudomonas aeruginosa. this finding of relatively low rates of gentamicin in enterobacteriaceae was surprising in view of the unregulated use of antibiotics until recent year ... | 1989 | 2599993 |
| differences in antimicrobial susceptibilities of clinical isolates in saudi arabia and the united states. | in vitro antimicrobial susceptibilities of 3,530 clinical isolates at king faisal specialist hospital and research center (kfsh), in riyadh, saudi arabia, were compared with those of 11,041 bacterial isolates at two hospitals of comparable size in the united states. the gram-negative bacteria, especially escherichia coli, proteus-morganella group, enterobacter sp, serratia marcescens, and pseudomonas aeruginosa were generally more resistant to ampicillin, carbenicillin, cephalosporin, gentamicin ... | 1987 | 3586042 |
| antimicrobial resistance of bacterial pathogens at two tertiary-care centers, in riyadh and texas. | antimicrobial resistance of bacterial pathogens usually varies from one geographic location to another. during the last 20 years, outbreaks of disease caused by multiresistant bacteria have occurred with higher frequency in developing countries. we investigated the antimicrobial resistance patterns of bacteria isolated in 1992 from two tertiary-care centers, in riyadh and texas. of the 8841 strains used, 5318 were isolated from clinical specimens of patients at king faisal specialist hospital an ... | 1994 | 7997964 |
| re-evaluation of pneumonia requiring admission to an intensive care unit: a prospective study. | appropriate treatment of severe community and hospital acquired pneumonias requiring admission to a medical intensive care unit depends on knowledge of the likely aetiological agents in any community. little is known about the pattern and outcome of patients with such pneumonias in saudi arabia. | 1994 | 8153944 |
| antimicrobial resistance and prevalence of extended spectrum beta-lactamase among clinical isolates of gram-negative bacteria in riyadh. | the activity of ciprofloxacin, imipenem and 12 other commonly used antibiotics was evaluated against 106 documented clinical isolates from a medical intensive care unit (icu). the resistance rates to ceftriaxone, cefotaxime, aztreonam and ceftazidime were 42, 25, 24 and 21%, respectively. apart from pseudomonas aeruginosa, all isolates were sensitive to ciprofloxacin and imipenem. complete cross resistance among tested beta-lactam groups was uniformly evident in enterobacter cloacae, citrobacter ... | 1995 | 8667034 |
| bacteriologic profile and drug resistance in pediatric patients with symptomatic bacteriuria. | the bacteriologic profile in 1081 pediatric patients with culture-positive symptomatic bacteriuria was studied over a 30-month period in a 500-bed acute care hospital in riyadh, saudi arabia. microbial isolates were considered significant if their numbers equaled or exceeded 10,000 colony-forming units/ml in symptomatic patients. escherichia coli was the most common causative agent of urinary tract infections (55.1%), followed by pseudomonas aeruginosa (11.9%), klebsiella pneumoniae (10.0%), and ... | 1996 | 8733990 |
| rate, risk factors and outcomes of catheter-related bloodstream infection in a paediatric intensive care unit in saudi arabia. | the aim of this study was to determine the rate, risk factors and outcomes of catheter-related bloodstream infections (crbsis) in patients in a paediatric intensive care unit (picu). a prospective cohort study was performed in king abdulaziz medical city, riyadh, saudi arabia; a 650-bed academic/tertiary care centre with a combined 10-bed medical and surgical picu. all patients admitted to the picu from july 2000 to february 2003 who had a central line placed were monitored for the development o ... | 2006 | 16307822 |
| hospital- and community-acquired infections: a point prevalence and risk factors survey in a tertiary care center in saudi arabia. | point prevalence studies are useful in revealing the prevalence of hospital-acquired infections (hais) and community-acquired infections (cais). such information allows prioritization of infection control resources and aids in overall hospital expenditure cut-backs. | 2006 | 16678467 |
| clinical profile of saudi children with bronchiectasis. | this study represents the experience of a tertiary care center in saudi arabia on non-cystic fibrosis bronchiectasis. | 2007 | 17337827 |
| antimicrobial resistance among clinical isolates of pseudomonas aeruginosa from patients in a teaching hospital, riyadh, saudi arabia, 2001-2005. | antimicrobial resistance to nine anti-pseudomonal agents (azteronam, ceftazidime, cefepime, piperacillin/tazobactam, imipenem, meropenem, ciprofloxacin, amikacin and gentamicin), the magnitude of multidrug resistance, associated underlying conditions, and mortality among patients with pseudomonas aeruginosa isolates from king khalid university hospital, riyadh, saudi arabia from 2001 to 2005 were determined. the results showed that antimicrobial resistance among p. aeruginosa is gradually increa ... | 2007 | 17515646 |
| prevalence of antimicrobial resistance among gram-negative isolates in an adult intensive care unit at a tertiary care center in saudi arabia. | patients in the icu have encountered an increasing emergence and spread of antibiotic-resistant pathogens. we examined patterns of antimicrobial susceptibility in gram-negative isolates to commonly used drugs in an adult icu at a tertiary care hospital in riyadh, saudi arabia. | 2010 | 20697174 |
| antimicrobial-resistant bacteria in a general intensive care unit in saudi arabia. | to assess the prevalence of multi-drug resistant (mdr) bacteria causing infections in patients at the intensive care units (icus) of riyadh military hospital (rmh), as well as their antimicrobial resistance patterns for one year. | 2010 | 21135998 |
| extended-spectrum and metallo-beta-lactamases among ceftazidime-resistant pseudomonas aeruginosa in riyadh, saudi arabia. | we investigated the extended-spectrum (esbls) and metallo-beta-lactamases (mbls) among pseudomonas aeruginosa isolates in saudi arabia. disc susceptibility testing was performed on 200 p. aeruginosa isolates collected during 2010 at the armed forces hospital in riyadh, with mic testing and phenotypic screening for esbls and mbls carried out on those found to be ceftazidime resistant. genes for esbls and mbls were sought by pcr. thirty-nine (19.5%) p. aeruginosa isolates were ceftazidime resistan ... | 2012 | 22546765 |