Publications

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bartonella henselae igg antibodies are prevalent in dogs from southeastern usa.in contrast to the large body of literature regarding bartonella henselae in humans and cats, there is little information about b. henselae as an infectious agent in dogs. due to the paucity of information regarding the b. henselae serology in dogs, we performed a cross-sectional serosurvey using b. henselae antigen in order to compare the seroprevalence between sick and healthy dogs from the south-eastern usa. ninety-nine sera were collected from clinically healthy dogs. three hundred and one s ...200415369661
comparison of results for serologic testing and a polymerase chain reaction assay to determine the prevalence of stray dogs in eastern tennessee seropositive to ehrlichia canis.to determine the prevalence of stray dogs in eastern tennessee seropositive to ehrlichia canis and examine the correlation between results for an elisa, indirect immunofluorescent antibody (ifa) test, and polymerase chain reaction (pcr) assay.200415478765
antinuclear antibodies can be detected in dog sera reactive to bartonella vinsonii subsp. berkhoffii, ehrlichia canis, or leishmania infantum antigens.the presence of antinuclear antibodies (anas) is used to support a clinical diagnosis of systemic lupus erythematosus (sle) in dogs. however, clinicians must interpret the detection of anas with caution, particularly in light of increasing evidence that dogs with known bacterial and protozoal infections can have high ana titers. retrospectively, medical records were reviewed for all dogs that were concurrently tested for antinuclear antigens and bartonella vinsonii (berkhoffii), ehrlichia canis, ...200414765731
characterization of the major antigenic protein 2 of ehrlichia canis and ehrlichia chaffeensis and its application for serodiagnosis of ehrlichiosis.canine monocytic ehrlichiosis, caused by ehrlichia canis or ehrlichia chaffeensis, can result in clinical disease in naturally infected animals. coinfections with these agents may be common in certain areas of endemicity. currently, a species-specific method for serological diagnosis of monocytic ehrlichiosis is not available. previously, we developed two indirect enzyme-linked immunosorbent assays (elisas) using the major antigenic protein 2 (map2) of e. chaffeensis and e. canis. in this study, ...200312853379
causes of uveitis in dogs: 102 cases (1989-2000).uveitis is one of the most common ocular diseases and one of the most common causes of blindness in dogs. the purpose of this retrospective study was to correlate the signalment, history, clinical signs and ophthalmic findings of dogs with uveitis with the underlying etiology. we conducted a retrospective study of 102 dogs presented to the ncsu-vth from 1989 to 2000 with clinical signs of uveitis. medical records of dogs presented for uveitis were reviewed. dogs were included in the study only i ...200212071865
seroprevalence of ehrlichia canis, ehrlichia equi, and ehrlichia risticii in sick dogs from north carolina and virginia.ehrlichia canis, e. equi, and e. risticii seroprevalence was determined by microimmunofluorescent antibody testing (ifa) in a sequential population of 1,845 sick dogs admitted during a 1-year period to the north carolina state university veterinary teaching hospital. a seroreactor was defined by a reciprocal ifa titer of > or =80 to e. canis, e. equi, or e. risticii antigens. of the 48 ifa seroreactors, 44 dogs were seroreactive to e. canis, 21 to e. equi, and 0 to e. risticii. seventeen dogs re ...200010668817
granulocytic ehrlichiosis in dogs from north carolina and virginia.medical records of 3 dogs from north carolina and 3 dogs from virginia with ehrlichial morulae in circulating neutrophils were studied retrospectively. two clinically distinct disease syndromes, including chronic, moderate to severe anemia (n = 3) and polyarthritis (n = 2) were associated with canine granulocytic ehrlichiosis (cge) in these dogs. one dog was clinically healthy, and abnormalities were not detected during physical examination. clinical signs were nonspecific and included fever, le ...19989560760
immunoblot analysis of the immunoglobulin g response to ehrlichia canis in dogs: an international survey.historically, considerable variation has been reported in the type and severity of clinical and hematologic abnormalities associated with canine ehrlichiosis. because of difficulties associated with the isolation of intracellular monocytic ehrlichia species in tissue culture systems, few e. canis isolates are available for comparative microbiologic studies. to address the issue of potential e. canis antigenic diversity in different regions of the world, dog sera reactive by indirect fluorescent ...19979087922
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