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the impact of infection with human metapneumovirus and other respiratory viruses in young infants and children at high risk for severe pulmonary disease.we conducted a prospective, observational study to characterize the clinical manifestations of respiratory infections caused by human metapneumovirus (hmpv) and other viruses in 194 premature infants and young children with chronic lung disease or congenital heart disease in buenos aires. children had 567 episodes of respiratory illness and were monitored until they were 2 years old or until the completion of the study. hmpv elicited 12 infections (2%) year-round; 30% were of moderate or greater ...200616652283
natural history of human respiratory syncytial virus inferred from phylogenetic analysis of the attachment (g) glycoprotein with a 60-nucleotide duplication.a total of 47 clinical samples were identified during an active surveillance program of respiratory infections in buenos aires (ba) (1999 to 2004) that contained sequences of human respiratory syncytial virus (hrsv) with a 60-nucleotide duplication in the attachment (g) protein gene. this duplication was analogous to that previously described for other three viruses also isolated in buenos aires in 1999 (a. trento et al., j. gen. virol. 84:3115-3120, 2003). phylogenetic analysis indicated that b ...200616378999
intragroup antigenic diversity of human respiratory syncytial virus (group a) isolated in argentina and chile.the intragroup antigenic diversity of the g glycoprotein of 226 human respiratory syncytial virus (hrsv) strains isolated in buenos aires (argentina) and santiago (chile) between 1995 and 2002 was evaluated by elisa with a panel of 14 anti-g monoclonal antibodies (mabs). out of 226 strains characterized, 172 (76%) belonged to group a and 54 (24%) to group b. strains from both groups cocirculated throughout the study period in both countries, except in 1996, 2000, and 2002 when only group a strai ...200516121383
molecular epidemiology of human respiratory syncytial virus subgroup a over a six-year period (1999-2004) in argentina.human respiratory syncytial virus (hrsv) is the main viral cause of acute lower respiratory tract infections in children. little information about the molecular epidemiology of hrsv in developing countries, such as argentina, is available. by rt-pcr, we subgrouped 353 hrsv isolates over six consecutive epidemic seasons (1999-2004) and few isolates from 1997. between them, 232 (65.7%) belonged to subgroup a and 121 (34.3%) to subgroup b. therefore, the nucleotide, amino-acid variability and phylo ...200516121371
genetic and antigenic variability of human respiratory syncytial virus (groups a and b) isolated over seven consecutive seasons in argentina (1995 to 2001).the genetic and antigenic variability of human respiratory syncytial virus (hrsv) strains isolated in buenos aires from 1995 to 2001 was evaluated by partial nucleotide sequencing of the g gene and enzyme-linked immunosorbent assay analysis with anti-g monoclonal antibodies. phylogenetic analyses showed that 37 group a strains clustered into five genotypes, whereas 20 group b strains clustered into three genotypes. group a showed more genetic variability than group b. a close correlation between ...200515872254
antigenic and genetic variability of human respiratory syncytial viruses (group a) isolated in uruguay and argentina: 1993-2001.the antigenic and genetic diversity of g glycoprotein from 25 human respiratory viruses (group a) isolated during nine consecutive epidemics (1993-2001) in montevideo, uruguay, and 7 strains isolated in buenos aires, argentina, in the same period were analyzed. genetic variability was evaluated by partial sequence of the g protein gene. phylogenetic analysis indicated that most uruguayan and argentinean group a isolates clustered into three genotypes: ga5, ga2, and ga1. some strains clustered in ...200312938207
acute lower respiratory infections due to respiratory syncytial virus and adenovirus among hospitalized children from argentina.acute lower respiratory infection (alri) is one of the main causes of morbidity and mortality in small children.19989645999
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