Publications

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an outbreak of equid herpesvirus abortion in new south wales.thirty-three of the 44 mares on a thoroughbred stud in new south wales aborted or lost foals within one day of birth. gross pathological and histological changes were in keeping with equid herpesvirus i (ehv-1) abortion. in the six foals that underwent virological examination, ehv was isolated and typed as ehv-1 by restriction endonuclease analysis. ehv-1 abortion had not occurred previously on this stud and the source of the infection was not identified.19911646102
outbreak of equine herpesvirus abortion in the hunter valley, new south wales. 19836309512
equine herpesvirus abortion in australia 1977 to 1982.until 1977 no case of abortion caused by equine herpesvirus 1 (ehv1) had been recorded in australia although the virus, called equine rhinopneumonitis virus, had been known to have been present at least since 1962. outbreaks of ehv1 abortion occurred in new south wales in 1977 and in 1981. sporadic cases of ehv1 abortion had been confirmed in some parts of australia each year since 1975. it was concluded that an abortigenic subtype of ehv1 had been introduced to australia in 1977 and that the pr ...19836315394
seroprevalence of equine herpesvirus 1 in thoroughbred foals before and after weaning.to investigate the seroprevalence of equine herpesvirus 1 in foals around weaning and after weaning on two large thoroughbred farms using a type-specific enzyme-linked immunosorbent assay to determine exposure to infection.19989830568
epidemiological studies of equine herpesvirus 1 (ehv-1) in thoroughbred foals: a review of studies conducted in the hunter valley of new south wales between 1995 and 1997.sero-epidemiological studies conducted between 1995 and 1997 on two large thoroughbred stud farms in the hunter valley of nsw showed clear evidence of ehv-1 infection in foals as young as 30 days of age. similarly, serological evidence suggested that these foals were infected with ehv-1 from their dams or from other lactating mares in the group, with subsequent foal to foal spread of infection prior to weaning. these studies also provided evidence of ehv-1 infection of foals at and subsequent to ...199910501158
epidemiology of ehv-1 and ehv-4 in the mare and foal populations on a hunter valley stud farm: are mares the source of ehv-1 for unweaned foals.the prevalence of ehv-1 and ehv-4 antibody-positive horses was determined using a type specific elisa on serum samples collected from 229 mares and their foals resident on a large thoroughbred stud farm in the hunter valley of new south wales in february 1995. more than 99% of all mares and foals tested were ehv-4 antibody positive, while the prevalence of ehv-1 antibody positive mares and foals were 26.2 and 11.4%, respectively. examination of the elisa absorbance data for the individual mares ...199910501159
incidence of equine herpesvirus 1 infection in thoroughbred weanlings on two stud farms. 200010840577
serological responses of mares and weanlings following vaccination with an inactivated whole virus equine herpesvirus 1 and equine herpesvirus 4 vaccine.equine herpesvirus 1 (ehv-1) is a major cause of respiratory disease and abortion in horses worldwide. although some vaccines have been shown experimentally to reduce disease, there are few reports of the responses to vaccination in the field. this study measured antibody responses to vaccination of 159 mares (aged 4-17 years) and 101 foals (aged 3-6 months) on a large stud farm with a killed whole virus ehv-1/4 vaccine used as per the manufacturer's recommendations. using an ehv glycoprotein d ...200212119135
seroprevalence of equine herpesvirus 1 in mares and foals on a large hunter valley stud farm in years pre- and postvaccination.to examine the prevalence of equine herpesvirus 1 antibody in mares and foals on a large hunter valley thoroughbred stud farm in new south wales before and after the introduction of an inactivated whole virus vaccine.200315084039
detection of ehv-1 and ehv-4 dna in unweaned thoroughbred foals from vaccinated mares on a large stud farm.a silent cycle of equine herpesvirus 1 infection has been described following epidemiological studies in unvaccinated mares and foals. in 1997, an inactivated whole virus ehv-1 and ehv-4 vaccine was released commercially in australia and used on many stud farms. however, it was not known what effect vaccination might have on the cycle of infection of ehv-1.200415163042
ehv-1 and ehv-4 infection in vaccinated mares and their foals.a silent cycle of equine herpesvirus 1 infection was described following epidemiological studies of unvaccinated mares and foals on a hunter valley stud farm. following the introduction of routine vaccination with an inactivated whole virus equine herpesvirus 1 (ehv-1) and equine herpesvirus 4 (ehv-4) vaccine in 1997, a subsequent study identified excretion of ehv-1 and ehv-4 in nasal swab samples tested by pcr from vaccinated mares and their unweaned, unvaccinated foals. the current sero-epidem ...200616513181
in vitro transposon mutagenesis of an equine herpesvirus 1 genome cloned as a bacterial artificial chromosome.the 150-kbp genome of the alphaherpesvirus equine herpesvirus 1 (ehv-1) strain hvs25a was cloned as a bacterial artificial chromosome (ehv-1 bac), with mini f plasmid sequences inserted between genes 62 and 63. transfection of ehv-1 bac dna purified from e. coli gave rise to progeny virus that had a similar growth rate and yield in mammalian cell culture to those of parental wild-type ehv-1. using in vitro mutagenesis with a mu transposon, a large library of ehv-1 bac mutants was generated, and ...200616855811
equine herpesvirus infections in yearlings in south-east queensland.twelve nasal swabs were collected from yearling horses with respiratory distress and tested for equid herpesvirus 1 (ehv-1) and equid herpesvirus 4 (ehv-4) by real-time pcr targeting the glycoprotein b gene. all samples were negative for ehv-1; however, 3 were positive for ehv-4. when these samples were tested for ehv-2 and ehv-5 by pcr, all samples were negative for ehv-2 and 11 were positive for ehv-5. all three samples that were positive for ehv-4 were also positive for ehv-5. these three sam ...200818677574
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