| trypanosoma cruzi: seroprevalence detected in the blood bank of the instituto nacional de pediatría, mexico city, in the period 2004 through 2009. | background: the second most common mode of trypanosoma cruzi or chagas disease transmission is via therapeutic blood transfusion. in mexico, control of t. cruzi is still in its initial phase; in fact, there are only 14 studies published covering 10 states on t. cruzi seroprevalence in donated blood in mexico. here we present the results of 5 years of trypanosomiasis screening in the blood bank of the instituto nacional de pediatría. study design and methods: samples from all blood donated in the ... | 2011 | 21880049 |
| knowledge deficits regarding chagas disease may place mexico's blood supply at risk. | prevention of transfusion-related chagas disease in mexico city depends on targeted questionnaire-based screening of donors by nurses at blood banks. to assess potential problems with this strategy, surveys were distributed to the nurses who screen donors in a random sampling of nine blood banks in mexico city, to measure appropriate knowledge about chagas disease. we found that 80% (95% ci 68-92%) of nurses answered at least one of the three donor risk factor questions incorrectly, which may fa ... | 2010 | 20688572 |
| [antibodies against t. cruzi in patients with dilated cardiomyopathy in tuxtla gutierrez, chiapas]. | chagas disease is caused by the flagellate protozoan t: cruzi. seroepidemiological surveys in chiapas, mexico have shown seropositive individuals, therefore, we searched for people affected by the chronic form of chagas disease which involves the heart, causing a chronic, progressive and fatal disease called chronic chagasic cardiopathy (ccc). | 2005 | 16366169 |
| blood transfusion and iatrogenic risks in mexico city. anti-trypanosoma cruzi seroprevalence in 43,048 blood donors, evaluation of parasitemia, and electrocardiogram findings in seropositive. | iatrogenous transmission of trypanosoma cruzi by blood transfusion was suggested as a potential risk by pellegrino (1949). seropositive blood donors in mexico were first reported in 1978, however, limited information is available due to small sampling, the use of heterogeneous serologic assays, and geographically limited studies. a wide survey carried out in 18 out of the 32 states of mexico, showed a national mean of 1.6% seropositive among 64,969 donors, ranging from 0.2 to 2.8%. in the presen ... | 2005 | 16021296 |
| risk factors associated with house infestation by the chagas disease vector triatoma pallidipennis in cuernavaca metropolitan area, mexico. | chagas disease caused by infection with trypanosoma cruzi chagas (kinetoplastida: trypanosomatidae) is widespread in mexico, transmitted by various triatomine bugs (hemiptera: reduviidae). the only domestic vector in cuernavaca (population 650 000) is triatoma pallidipennis (ståhl) with t. cruzi seroprevalence ranging from 1% to 9% in the resident human population. we surveyed possible risk factors for t. pallidipennis infestation at cuernavaca (altitude 1200-2200 m) on south-western slopes of t ... | 2005 | 15958028 |
| standardization of micro-enzyme-linked immunosorbent assay (elisa) and western blot for detection of trypanosoma cruzi antibodies using extracts from mexican strains as antigens. | this report describes two assays for the detection of anti-trypanosoma cruzi antibodies using mexican strains of the parasite and the concordance with two assays previously evaluated at the instituto nacional de cardiología ignacio chávez in mexico city. | 2001 | 11578752 |
| american trypanosomiasis (chagas' disease) and blood banking in mexico city: seroprevalence and its potential transfusional transmission risk. | american trypanosomiasis (chagas' disease), an anthropozoonosis fairly common in rural latin america, has become an urban disease due to continuous migration, intra- and internationally. blood transfusion, the second important pathway for transmission, increases its impact. recognition of seropositive subjects among blood donors is now recommended, and clinical and serological screening enforced. maneuvers to inactivate or remove trypanosoma cruzi present in collected blood are recommended. | 1999 | 10596460 |
| [detection of antibodies against trypanosoma cruzi in blood donors]. | american trypanosomiasis is an endemic disease in mexico. blood transfusion has been recognized as the second main mechanism of transmission in south american countries. there is no definitive information available for mexico. we obtained the prevalence of igg antibodies against trypanosoma cruzi among 1076 blood donors at the instituto nacional de cardiología "ignacio chávez" in mexico city. we used an antigen freshly prepared from local isolates, and the complete and soluble antigen preparatio ... | 1993 | 8470021 |
| persistence of trypanosoma cruzi in chronic chagasic cardiopathy patients. | although patients with chronic chagasic cardiopathy do have a strong immune response against trypanosoma cruzi, they have transient and low parasitemia as well as tissue amastigote nests. when conventional studies were carried out, demonstration of such abnormalities is minimally achieved. molecular biology may provide the best tools to demonstrate parasite persistence, which could be pathogenic in this progressive disease. | 2001 | 11282179 |
| seroprevalence of trypanosoma cruzi in kidney transplant donors and recipients in mexico city. | infectious diseases are common causes of morbidity and mortality among kidney transplant recipients. chagas disease (cd) has been recognized as an emerging infectious complication of transplantation caused by the parasite trypanosoma cruzi. cd is prevalent in mexico, particularly in the southern coastal region. the impact on mexican kidney transplant programs has not been previously studied prospectively. from 2009 through 2010, serum samples from 59 kidney transplant donors and 405 renal transp ... | 2013 | 23901935 |
| the risk of transfusion transmission of chagas disease in mexico city. | | 2000 | 10827270 |
| maternal fetal transmission of trypanosoma cruzi: a problem of public health little studied in mexico. | the first case of neonatal chagas was reported in mexico in 1998, but there have been no studies since then. therefore, we investigated the rates of congenital infection of trypanosoma cruzi by examining the seroprevalence among 1448 pregnant women in oaxaca, jalisco and mexico city. we performed elisas to screen for recombinant and total antigens in mothers, and examined the frequency of congenital t. cruzi transmission by pcr with cord blood and antibody testing in children when they reached t ... | 2012 | 22683499 |