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hepatocellular carcinoma - united states, 2001-2006.liver cancer, primarily hepatocellular carcinoma (hcc), is the third leading cause of death from cancer worldwide and the ninth leading cause of cancer deaths in the united states. chronic hepatitis b virus (hbv) and hepatitis c virus (hcv) infections account for an estimated 78% of global hcc cases. to determine trends in hcc incidence in the united states, cdc analyzed data for the period 2001-2006 (the most recent data available) from cdc's national program of cancer registries (npcr) and the ...201020448528
hepatitis-associated (australia) antigen in hawaii. 19705490962
hepatitis b virus infection in honolulu students.to determine hepatitis b virus (hbv) carrier and infection rates and hbv epidemiology in honolulu students.19938414830
hepatitis associated antigen (haa) in hawaii. 19705517044
hepatitis b and c virus serologies among japanese americans with hepatocellular carcinoma.a cohort of 5924 japanese american men was examined between 1967 and 1970 for hepatocellular carcinoma (hcc). by 1992, 24 incident cases of hcc were histologically confirmed in the group. frozen serum samples from the 24 men with hcc and 72 age-matched controls were tested for hepatitis b surface antigen (hbsag), antibodies to hepatitis b core antigen, antibodies to hbsag, and antibodies to hepatitis c virus. hbsag was detected in 15 (62.5%) of 24 hcc cases compared with 2 (2.8%) of 72 controls ...19968648223
genotype and phylogenetic characterization of hepatitis b virus among multi-ethnic cohort in hawaii.hepatitis b virus (hbv) genomes in carriers from hawaii have not been evaluated previously. the aim of the present study was to evaluate the distribution of hbv genotypes and their clinical relevance in hawaii.200415259069
in situ detection of hepatitis b, c, and g virus nucleic acids in human hepatocellular carcinoma tissues from different geographic regions.we performed a retrospective study to determine the prevalence of hepatitis b virus (hbv), hepatitis c virus (hcv), and hepatitis g virus (hgv) genomes in formalin-fixed, paraffin-embedded liver tissues from hepatocellular carcinoma (hcc) patients in various geographic areas. the prevalence of each hepatitis virus in the liver tissues that have both carcinoma and noncarcinoma regions was different among the countries. hcv was the most prevalent in japan (75 of 122 [61.5%]), spain (9 of 15 [60%]) ...19989696026
near elimination of hepatitis b virus infections among hawaii elementary school children after universal infant hepatitis b vaccination.hawaii implemented routine infant hepatitis b vaccination in 1992 and required it for school entry in 1997. previously, in 1989, a serologic survey among hawaii school children in grades 1 to 3 indicated that 1.6% had chronic hepatitis b virus infection, and 2.1% had resolved infection. we conducted a follow-up survey to examine changes in hepatitis b virus infection rates.200617015529
mutations of p53 gene in hepatocellular carcinoma: roles of hepatitis b virus and aflatoxin contamination in the diet.mutations of the p53 tumor suppressor gene have been reported in 50% of patients with hepatocellular carcinoma (hcc) from china and south africa. these reports suggested an association of p53 mutations with high levels of aflatoxin in the diet. most studies of p53 and hcc, however, have not fully evaluated the possible role of the hepatitis b virus (hbv). aflatoxin is a substance produced by food mold that is known to cause hcc in experimental animals.19921279184
the honolulu liver disease cluster at the medical center: its mysteries and challenges.in 2013, physicians at the honolulu queen's medical center (qmc) noticed that seven liver disease patients reported the use of oxyelite pro (oep), a widely consumed dietary supplement (ds). assuming a temporal association between oep use and disease, they argued that oep was the cause of this mysterious cluster. subsequent reexamination, however, has revealed that this qmc cohort is heterogeneous and not a cluster with a single agent causing a single disease. it is heterogeneous because patients ...201627043544
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