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[comparison of sequences of hepatitis b virus s gene fragment in eight cities of china].sequencing and comparative analysis of 52nd to 512th nucleotide of s gene in hepatitis b virus (hbv) were conducted in 43 cases of sero-positive and 52 cases of sero-negative hb from eight cities, including changchun, datong, hangzhou, shenzhen, qingtao, xi'an, kunming and lahsa, to study the relationship between focal variation of hbv s gene and seronegative hb. it was found that sequences of hbv s gene fragment in the same genotype were more conservative, most of its mutation happened randomly ...19979812589
[establishment of a method for classification of hbv genome and it's application].by using the techniques of pcr and restriction fragment length polymorphism (rflp), we established a classification method for hbv genome based on viral s gene of asymptomatic hbv carriers (asc).199912759965
residual risk of transfusion-transmitted viral infections in shenzhen, china, 2001 through 2004.there are no current estimates of the residual risks of transmission by blood of hepatitis b virus (hbv) or hepatitis c virus (hcv) and human immunodeficiency virus (hiv) in china. such estimates are an essential prerequisite to monitoring and improving transfusion safety as well as supporting evidence based assessment of the value of implementing new screening interventions.200717319836
clinical and virological characteristics of hepatitis b virus subgenotypes ba, c1, and c2 in china.hepatitis b virus (hbv) subgenotypes ba, c1 (cs), and c2 (ce) are the most prevalent hbv variants in china. to investigate the virological characteristics of these subgenotypes and their clinical implications, we enrolled a cohort of 211 patients in the guangdong province of china, including 132 with chronic hepatitis b virus infection (ch), 32 with liver cirrhosis (lc), and 47 with hepatocellular carcinoma (hcc) according to clinical examination, liver function test, and ultrasonograph results. ...200717376881
[status of vaccination against hepatitis b among postgraduate students in medical higher education institutions in guangzhou].to investigate the status of vaccination against hepatitis b among postgraduate students of medical institutions of higher education in guangzhou.200717653308
[distribution of hepatitis b virus genotypes in patients with chronic hepatitis b virus infection among 12 cities in china].to investigate the distribution of hepatitis b virus (hbv) genotypes in patients with chronic hbv infection among 11 cities of china.200717850692
two hbv dna+/hbsag- blood donors identified by hbv nat in shenzhen, china.in order to further improve blood safety, mini-pool (mp) nucleic acid testing (nat) was implemented to screen samples negative for hepatitis b surface antigen (hbsag), anti-hepatitis c virus (anti-hcv), anti-human immunodeficiency virus (anti-hiv), syphilis (anti-treponemal antibody) and with normal alt.200919487161
[relationship of fatty liver with hbv infection, hyperlipidemia and abnormal alanine aminotransferase].to investigate the prevalence of fatty liver in guangzhou and its relation to hepatitis b virus (hbv) infection, hyperlipidemia and abnormal alanine aminotransferase (alt).200920104761
infection status and risk factors of hiv, hbv, hcv, and syphilis among drug users in guangdong, china--a cross-sectional study.china has witnessed a remarkable increase in sexually transmitted infections (stis) and hiv. the study is to assess the prevalence of hiv, hbv, hcv and syphilis and related risk factors among drug users in mandatory detoxification center qingyuan, guangdong, china.201021040549
clinical and virological characteristics of lamivudine resistance in chronic hepatitis b patients: a single center experience.we have investigated the characteristics of lamivudine-resistant strains in patients with chronic hepatitis b in guangdong, china, where the predominant genotypes are b and c. two hundred forty-seven patients treated with lamivudine in nanfang hospital were followed-up. patients with hepatitis b e antigen (hbeag) positive and hepatitis b virus (hbv)-dna levels over 7.5 x 10(6) copies/ml at baseline had a shorter time to the selection of ymdd mutant (p = 0.02 and 0.00, respectively). the detectio ...200515648063
efficacy of intramuscular matrine in the treatment of chronic hepatitis b.hepatitis b virus (hbv) infection, a global public health problem, is the leading cause of cirrhosis and hepatocellular carcinoma (hcc) worldwide. there are more than 350 million hbv carriers in the world and up to one million die annually due to hepatitis b associated liver disease. so far no optimal treatment is available for patients with chronic hepatitis b. in the paper we investigated the efficacy of intramuscular matrine in the treatment of chronic hepatitis b.200414969841
[Distribution and clinical significance of HBV genotypes in patients with HBV infection in 30 regions of China].To explore the distribution and clinical significance of HBV genotypes in patients with HBV infection in China.201121863637
[association of immune response to hepatitis b vaccine with hla-drb1*02, 07, 09 genes in the population of han nationality in guangdong province].to study the association between immune response to hepatitis b vaccine and hla-drb1*02, 07, 09 genes in the population of han nationality in guangdong province.200212390851
[study on the distribution of sub-genotype b on hepatitis b virus in patients with chronic hbv infection from 4 cities of china].to investigate the distribution of sub-genotype b on hepatitis b virus (hbv) in patients with hbv chronic infection from 4 cities (beijing, shijiazhuang, wenzhou and shenzhen) of china.200818785479
perinatal transmission of hepatitis b virus infection and vaccination in china.hepatitis b remains one of the most important infectious diseases in china. in 1980, an overall hepatitis b virus (hbv) infection rate of 42.6% was reported and a hepatitis b surface antigen (hbsag) carrier rate of 10.3%. hbsag positivity among children under 1 year of age ranged from 5.1% in beijing to 7% in guangdong. a peak in carrier rate was observed in 7 to 14 year olds, reaching 24% in guangdong. during the past decade, there has been no significant change in overall hbv carrier rates. ho ...19968786051
epidemiology of hepatitis b virus infection in south african chinese.the authors determined the age-specific prevalence of hepatitis b virus markers in 1,408 chinese who resided in south africa in 1983-1985. the small south african chinese community consists of original chinese settlers, almost all of whom migrated from the hepatitis b virus endemic mainland china province of guangdong, and their south african-born descendants. the chinese live among the white south african community, which has a very low hepatitis b virus carrier rate. the overall hepatitis b vi ...19883421246
hepatitis delta virus superinfection in guangzhou area.biopsy and autopsy specimens of liver tissues of two series of patients, one of adults and the other children suffering from hepatitis b virus (hbv) infection were used to evaluate hepatitis delta virus antigen (hdag) by direct immunoperoxidase staining method. the results showed that four hdag positive cases were found among 30 cases of hbv infected adult patients (13.3%), and 6 were found in 44 cases in the children series (13.6%). therefore, we are convinced that hepatitis delta virus (hdv) s ...19902119957
[application of multiplex pcr in genotyping of hepatitis b virus prevailing in guangdong province of china].to establish a convenient method for the genotyping of hepatitis b virus (hbv) using multiplex pcr.200212376255
[a sero-epidemiological study of hcv and hbv infection among intravenous drug abusers].to investigate hepatitis b and c virus infection in drug addicts in guangzhou.199912569756
stress in parents whose children are hepatitis b virus (hbv) carriers: a comparison of three groups in guangzhou, china.this study was conducted in guangzhou, china. it compared the responses on stress scales of three groups of parents: (1) parents of children with hbv attending a special health kindergarten; (2) parents of children with hbv who stayed at home; and (3) parents of healthy children attending ordinary kindergartens. parents of hbv infected children reported greater problems due to stress. this stress was correlated with parents' general health in the three groups. the groups did not differ in report ...19968937750
epidemiological, clinical and histological characteristics of hbv/hdv co-infection: a retrospective cross-sectional study in guangdong, china.the epidemiology of hepatitis d virus (hdv) in china is fairly unknown. the mechanisms whereby hdv leads to accelerated liver disease in hepatitis b virus (hbv)/hdv co-infected patients and the histological characteristics of chronic hepatitis d (chd) patients need further investigation.201425532128
knowledge of and attitudes towards hepatitis b and its transmission from mother to child among pregnant women in guangdong province, china.hepatitis b virus (hbv) infection remains a serious public health problem worldwide. mother-to-child transmission (mtct) of hbv is the major mode of transmission in hbv-endemic areas, including china, where little is known about pregnant women's knowledge of and attitudes towards hbv infection and mtct.201728575040
impact of hepatitis b vaccination among children in guangdong province, china.to evaluate the impact of the universal infant hepatitis b vaccination program on hepatitis b virus (hbv) infection in guangdong province, china.201222795176
disease burden from hepatitis b virus infection in guangdong province, china.to estimate the disease burden and financial burden attributed to hepatitis b virus (hbv) infection in guangdong province.201526540065
epidemiological and clinical characteristics of hepatitis b virus in hiv-infected patients in guangdong, china.this study investigated the epidemiological and clinical characteristics of hepatitis b virus (hbv) in hiv-infected adults at the time of antiretroviral therapy (art) initiation in guangdong province, china. a total of 2793 hiv-infected adults were enrolled between january 2004 and september 2011. demographic data and laboratory parameters were collected, hbv-dna levels were measured, and hbv genotypes were identified before art initiation. the prevalence of hepatitis b surface antigen (hbsag) i ...201626384940
[seroepidemiological analysis of hepatitis b among children aged 1-14 in 3 counties of guangdong province in 2013].to investigate the epidemic status of hepatitis b in children aged 1-14 in 3 counties of guangdong province in 2013, and to evaluate the effect of hepatitis control in children aged 1-14 after hepatitis b vaccine was integrated into the national immunization program in 2002 and catch-up vaccination was conducted from 2009 to 2011.201526733134
epidemiology of hepatitis b virus infection: results from a community-based study of 0.15 million residents in south china.limited information is available about the current epidemic status of hepatitis b virus (hbv) in guangdong province in south china, where hepatitis b is endemic. we sought to provide an up-to-date assessment of hepatitis b prevalence in a large population through a community-based study. a total of 169,211 local residents were recruited using the stratified cluster random sampling method from 2014 to 2015, and each participant's information was collected using an interviewer-administered questio ...201627819332
prevalence of hepatitis g virus infection and homology of different viral strains in southern china.to investigate the prevalence of hepatitis g virus (hgv) infection and to analyse the homology of different hgv strains in southern china.200212439930
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