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immunogenicity of a low-cost hepatitis b vaccine in the south african expanded programme on immunisation.a low-cost, 'flash' heat-inactivated hepatitis b vaccine with enhanced immunogenicity allowing for a relatively low dose (hepaccine b; cheil foods and chemicals, korea) was introduced into the south african expanded programme on immunisation during 1995 to immunise infants against hepatitis b. to determine the seroresponse of this vaccine in south africa, a country with a high hepatitis b virus (hbv) prevalence, a field trial was conducted in a rural health clinic.19989539933
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