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the frequency, distribution and effects of antibodies, to seven putative respiratory pathogens, on respiratory disease and weight gain in feedlot calves in ontario.during 1983-85, 279 calves requiring treatment for bovine respiratory disease and 290 comparison (control) animals from 15 different groups of feedlot calves were bled on arrival and again at 28 days postarrival. their sera were then analyzed for antibodies to seven putative respiratory pathogens. on arrival, the prevalences of indirect agglutination titers to pasteurella haemolytica, p. haemolytica cytotoxin, mycoplasma bovis and m. dispar were greater than 50%, the prevalence of titers to bovi ...19892766158
respiratory syncytial virus surveillance in various regions across canada. 19873791104
some respiratory and enteric diseases of cattle: an update.fibrinous pneumonia caused 40-45% of death losses in cattle shipped into bruce county, ontario. feeding corn silage within the first 2 weeks of arrival increased mortality. commingling cattle from different sources and keeping more than 110 cattle in a pen were detrimental. while use of antimicrobials in the starter ration was beneficial, prophylactic use of antimicrobials in the water was not. mortality was directly proportional to morbidity and treatment costs. vaccinating against any respirat ...19846738491
surveillance for outbreaks of respiratory tract infections in nursing homes.outbreaks of respiratory tract infections are common in long-term care facilities for older people. the objective of our study was to determine both the frequency of such outbreaks and their clinical and epidemiological features.200010789627
costs associated with infant bronchiolitis in the baffin region of nunavut.objective. although infants living in the north of canada have been reported to have one of the highest rates of hospital admission for bronchiolitis in the world, the economic effects of this condition have not been reported. passive immunization against the respiratory syncytial virus, the most common causative agent of infant bronchiolitis, is available.200515776991
diseases and pathogens associated with mortality in ontario beef feedlots.this study determined the prevalence of diseases and pathogens associated with mortality or severe morbidity in 72 ontario beef feedlots in calves that died or were euthanized within 60 days after arrival. routine pathologic and microbiologic investigations, as well as immunohistochemical staining for detection of bovine viral diarrhea virus (bvdv) antigen, were performed on 99 calves that died or were euthanized within 60 days after arrival. major disease conditions identified included fibrinos ...200616566254
seasonality of primary care utilization for respiratory diseases in ontario: a time-series analysis.respiratory diseases represent a significant burden in primary care. determining the temporal variation of the overall burden of respiratory diseases on the health care system and their potential causes are keys to understanding disease dynamics in populations and can contribute to the rational management of health care resources.200818662391
risk-scoring tool for respiratory syncytial virus prophylaxis in premature infants born at 33-35 completed weeks' gestational age in canada.to study the impact of the risk-scoring tool (rst) as a strategy for targeting prophylaxis effectively in 33-35-week gestational age (ga) canadian infants who range from low to high risk by evaluating the subsequent incidence of respiratory syncytial virus (rsv) infections resulting in emergency room (er) visits and hospitalization.200919469698
predictive value of the respiratory syncytial virus risk-scoring tool in the term infant in canada.palivizumab prophylaxis against respiratory syncytial virus (rsv) infection has been widely adopted for high-risk infants during the rsv season, based on country-specific guidelines.200919604126
neonates investigated for influenza-like illness during the outbreak of pandemic h1n1 2009: trivial infections but major triage implications.we report eight cases of neonates (from birth to 25 days) admitted to the neonatal service of a teaching hospital with influenza-like illness during the outbreak of pandemic h1n1 2009, and discuss their management and infection control issues. empirical antibiotics were often promptly initiated and timely stopped when sepsis was ruled out. also, there was no pandemic h1n1-09 but influenza a (h3n2, n = 1), parainfluenza (type 3, n = 3) and respiratory syncytial virus (n = 1) have been isolated. t ...201020814838
changing costs and the impact on rsv prophylaxis.acquisition costs of palivizumab have increased in canada since 2007. this analysis aims to re-evaluate the cost effectiveness of palivizumab in canada for premature infants born between 32 and 35 weeks' gestational age using updated 2010 healthcare costs compared to those used in a 2007 decision analytic model.201021087075
respiratory virus infection and risk of invasive meningococcal disease in central ontario, canada.in temperate climates, invasive meningococcal disease (imd) incidence tends to coincide with or closely follow peak incidence of influenza virus infection; at a seasonal level, increased influenza activity frequently correlates with increased seasonal risk of imd.201021103353
the impact of prophylaxis on paediatric intensive care unit admissions for rsv infection: a retrospective, single-centre study.respiratory syncytial virus (rsv) is the leading cause of lower respiratory tract infections and hospitalizations in children aged <2 years. the aim of this retrospective, single-centre study was to examine the characteristics of patients admitted to a paediatric intensive care unit (picu) with rsv infection following the implementation of a rsv prophylaxis programme. electronic hospital medical records of all picu admissions for rsv infection were searched from 2003 to 2009. data on baseline de ...201021174120
community-acquired respiratory viruses and co-infection among patients of ontario sentinel practices, april 2009 to february 2010.respiratory viruses are known to cocirculate but this has not been described in detail during an influenza pandemic.201322883216
genetic diversity and evolutionary insights of respiratory syncytial virus a on1 genotype: global and local transmission dynamics.human respiratory syncytial virus (rsv) a on1 genotype, first detected in 2010 in ontario, canada, has been documented in 21 countries to date. this study investigated persistence and transmission dynamics of on1 by grouping 406 randomly selected rsv-positive specimens submitted to public health ontario from august 2011 to august 2012; rsv-a-positive specimens were genotyped. we identified 370 rsv-a (181 na1, 135 na2, 51 on1 3 ga5) and 36 rsv-b positive specimens. we aligned time-stamped second ...201526420660
incidence of hospitalization for respiratory syncytial virus infection amongst children in ontario, canada: a population-based study using validated health administrative data.rsv is a common illness among young children that causes significant morbidity and health care costs.201626958849
seasonal respiratory syncytial virus prophylaxis based on predetermined dates versus regional surveillance data.in ontario, canada, the respiratory syncytial virus (rsv) prophylaxis period onset is defined by a fixed-date set provincially each year and offset by local hospital rsv admission activity. inaccurate timing can result in inadequate or more costly prophylaxis.201323546534
bronchiolitis and pneumonia requiring hospitalization in young first nations children in northern ontario, canada.high rates of lower respiratory tract infection (lrti), including bronchiolitis and pneumonia, have been reported in inuit infants living in arctic canada. we examined rates of lrti in first nations canadian infants living in the sioux lookout zone, in northern ontario.201424751861
management of bronchiolitis in community hospitals in ontario: a multicentre cohort study.bronchiolitis is the leading cause of hospital admission for infants, but few studies have examined management of this condition in community hospital settings. we reviewed the management of children with bronchiolitis presenting to community hospitals in ontario.201626906352
genetic variability of human respiratory syncytial virus a strains circulating in ontario: a novel genotype with a 72 nucleotide g gene duplication.human respiratory syncytial virus (hrsv) is the main cause of acute lower respiratory infections in children under 2 years of age and causes repeated infections throughout life. we investigated the genetic variability of rsv-a circulating in ontario during 2010-2011 winter season by sequencing and phylogenetic analysis of the g glycoprotein gene.among the 201 consecutive rsv isolates studied, rsv-a (55.7%) was more commonly observed than rsv-b (42.3%). 59.8% and 90.1% of rsv-a infections were am ...201222470426
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