| berna: a century of immunobiological innovation. | at the time the swiss serum and vaccine institute berne (berna) was found in 1898, few vaccines or immune globulins were available. this short list included vaccines against cholera, typhoid fever, plague, smallpox and rabies and equine anti-tetanus and diphtheria immune globulins. furthermore, their use was restricted due to limited production capacity, uncertainty regarding safety and no public health infrastructure to promote their utilization. today, safe and effective vaccines exist for mor ... | 1999 | 10506402 |