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changes in the evolution of meningococcal disease, 2001-2008, catalonia (spain).reported cases of meningococcal disease between 1997 and 2008 were analyzed to determine the evolution after the introduction of a conjugated vaccine. in <6 years, the incidence rate of serogroup c fell from 7.6 to 0.6 per 100,000 persons/year in the periods before (1997-2000) and after (2001-2007) the introduction of the conjugate vaccine. in serogroup b, the reduction was from 15.4 to 11.1. in <20 years case-fatality-rate increased only in serogroup b (3% and 7.4%, p=0.026). serosubtype p1.15 ...200919200816
[prevalence of neisseria meningitidis carriers among the population of cerdanyola (barcelona)].to determine the prevalence of neisseria meningitidis (n. meningitidis) from healthy carriers and its resistance to penicillin in cerdanyola population. to asses which risk factors were associated with healthy carriers and compare some epidemiologic characteristics between people with penicillin sensitive and penicillin resistant strains.19958519816
epidemiology of vaccine-preventable invasive diseases in catalonia in the era of conjugate vaccines.we investigated the incidence and distribution of cases of invasive pneumococcal disease (ipd), invasive meningococcal disease (imd) and invasive hemophilus influenzae disease (ihid) notified by hospital laboratories to the microbiological reporting system of catalonia between 2005 and 2009. incidence rates were compared using the rate ratio (rr) and 95% ci were calculated. a value of p < 0.05 was considered statistically significant. of the 6,661 cases, 6,012 were ipd, 436 imd and 213 ihid. the ...201323303166
[haemophilus influenzae type b invasive disease and meningococcal disease: incidence and characteristics in barcelona, 1994-1995. work group ims-iuspc for surveillance and control of meningitis].the purpose of the study is to estimate the incidence of haemophilus influenzae type b invasive disease (hibid) and meningococcal disease (md) in barcelona (catalonia, spain) for the years 1994-1995.199910027177
[meningococcal disease in catalonia, spain (1990-1997)].we aimed to study the behavior of meningococcal disease in catalonia during the period 1990-1997, identifying the possible epidemic periods.200415511368
evaluation of travelers returning from the 1992 olympics in barcelona, spain: did they acquire resistant pneumococci and meningococci? 19957756515
meningococcal disease in catalonia 1 year after mass vaccination campaign with meningococcal group c polysaccharide vaccine.the aim of this study was to investigate the clinical and epidemiological characteristics of meningococcal disease in catalonia (spain) after vaccination with the polysaccharide vaccine.200314735381
dramatic decline of serogroup c meningococcal disease in catalonia (spain) after a mass vaccination campaign with meningococcal c conjugated vaccine.in the last quarter of the year 2000, the meningococcal c conjugated vaccine was incorporated into the routine vaccination schedule in catalonia (at 2, 4 and 6 months). in addition a vaccination campaign was carried out in children <6 years of age, with a coverage of 96.2%. the effectiveness of the vaccination in this age group during 2001 and the first 28 weeks of 2002 was 100% (94.27-100%). a vaccination campaign has been carried out in 6-19-year olds during 2001 and 2002, with a coverage rate ...200312531350
carriers of neisseria meningitidis in household contacts of meningococcal disease cases in catalonia (spain).a population-based study was carried out in catalonia (spain) from may 1998 to april 1999 to determine the prevalence of neisseria meningitidis strains in meningococcal disease (md) cases and their contacts, as well as the prevalence of meningococci in close contacts of patients with md, and risk factors for its carriage. a total of 364 close contacts of 87 patients with md were studied. throat samples were collected by hospital staff before rifampicin chemoprophylaxis was begun. for each contac ...200112081108
prevalence of neisseria meningitidis carriers in the school population of catalonia, spain.the aim of this study was to determine the prevalence of healthy neisseria meningitidis pharyngeal carriers in a representative sample of the catalonian school population, as well as its associated factors. the sample was divided into age groups: < or = 5, 6-7 and 13-14 years old. parents were given a questionnaire to collect information on sociodemographic and epidemiological variables. oropharyngeal swabs were collected with a cotton-tipped swab in an amies transport medium and cultured on tha ...200111811875
neisseria meningitidis: evolution of penicillin resistance and phenotype in a children's hospital in barcelona, spain.neisseria meningitidis is the most prevalent micro-organism involved in paediatric bacterial meningitis in the barcelona area in children over 3 mo of age and it is an important cause of morbidity and mortality in spain. a total of 498 strains of n. meningitidis, obtained between the years 1986 and 1997 from children with sepsis and/or meningitis, were characterized according to their serogroup and penicillin resistance; their distribution in serotypes and subtypes was studied from 1990. a decre ...200010914958
meningococcal disease in a large urban population (barcelona, 1987-1992): predictors of dismal prognosis. barcelona meningococcal disease surveillance group.studies on meningococcal disease in large urban communities have rarely been performed and are usually based on passive epidemiologic surveillance. active surveillance may provide new insights.199910547173
[bacteremia in 13 general hospitals of the province of barcelona. prospective study of 1,674 episodes. group of microbiologists of the county hospitals of catalonia].clinical and microbiological description of bacteremias seen in 13 regional hospitals of barcelona.19957654835
[epidemiology of the meningococcal disease in catalonia before and after vaccination against serogroup c].meningococcal disease remains a serious public health problem worldwide. in catalonia, after implementing the vaccination program, there has been a significant decrease in cases caused by meningococcus c.200920111820
the case-fatality rate of meningococcal disease in catalonia, 1990-1997.the objective was to analyse the case-fatality rate (cfr) of meningococcal disease (md) in catalonia, spain. a retrospective study was carried out. clinical histories of cases of md reported for the period 1990-1997 in catalonia were reviewed. for all cases, the variables gender, age, clinical type, y of presentation, province, phenotype and death by meningococcal disease were collected. the association between death and the other variables was studied by bivariate and unconditional logistic reg ...200415198184
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