| bacterial meningitis in johannesburg--1980-1982. | a 2-year retrospective study of aetiology, age distribution, seasonal variation and antimicrobial sensitivity patterns of bacteria isolated from patients with meningitis in five johannesburg hospitals for white, black, coloured and asian patients was performed. neisseria meningitidis was isolated most frequently, followed by streptococcus pneumoniae, haemophilus influenzae, escherichia coli and streptococcus group b. in the black population 73% of the meningococcal infections occurred in patient ... | 1984 | 6495110 |
| meningococcal disease in south africa, 1999-2002. | we describe the epidemiology of invasive meningococcal disease in south africa from august 1999 through july 2002, as reported to a laboratory-based surveillance system. neisseria meningitidis isolates were further characterized. in total, 854 cases of laboratory-confirmed disease were reported, with an annual incidence rate of 0.64/100,000 population. incidence was highest in infants < 1 year of age. serogroup b caused 41% of cases; serogroup a, 23%; serogroup y, 21%; serogroup c, 8%; and serog ... | 2007 | 17479891 |
| emergence of endemic serogroup w135 meningococcal disease associated with a high mortality rate in south africa. | in the african meningitis belt, neisseria meningitidis serogroup w135 has emerged as a cause of epidemic disease. the establishment of w135 as the predominant cause of endemic disease has not been described. | 2008 | 18181736 |
| increased incidence of meningococcal disease in hiv-infected individuals associated with higher case-fatality ratios in south africa. | we aimed to compare the incidence of meningococcal disease amongst hiv-infected and uninfected individuals and to evaluate whether hiv is a risk factor for mortality and bacteremia amongst patients with meningococcal disease. | 2010 | 20559040 |
| an outbreak of meningococcal meningitis in gauteng, spring 1996. | to describe a neisseria meningitidis outbreak in gauteng during the period 1 july to 31 december 1996. | 1999 | 10341827 |
| epidemic spread of subgroup iii of neisseria meningitidis serogroup a to south africa in 1996. | a total of 111 strains of neisseria meningitidis isolated during a meningitis outbreak in johannesburg, south africa, in 1996 were analyzed by serogrouping, arbitrarily primed polymerase chain reaction analysis, ribotyping, and multilocus enzyme electrophoresis. nineteen different clusters were identified, and typing patterns for the three techniques were comparable. of the 111 strains analyzed, 55 (49.5%) belonged to the serogroup a clone complex designated internationally as subgroup i-1. the ... | 1998 | 9827272 |
| clonal analysis of neisseria meningitidis serogroup b strains in south africa, 2002 to 2006: emergence of new clone st-4240/6688. | from august 1999 through july 2002, hyperinvasive neisseria meningitidis serogroup b (menb) clonal complexes (ccs), namely, st-32/et-5 (cc32) and st-41/44/lineage 3 (cc41/44), were predominant in the western cape province of south africa. this study analyzed menb invasive isolates from a national laboratory-based surveillance system that were collected from january 2002 through december 2006. isolates were characterized by pulsed-field gel electrophoresis (pfge) (n = 302), and multilocus sequenc ... | 2012 | 22972827 |