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genetic characterization of multidrug resistance in shigella spp. from japan.this study characterized the genetic basis of antimicrobial resistance of a number of shigella spp. isolated from humans from 2000 to 2004 in hiroshima prefecture, japan. a total of 26 isolates of shigella spp. were included in this study. antimicrobial susceptibility tests revealed high levels of resistance, especially to ampicillin, streptomycin, trimethoprim, tetracycline, nalidixic acid and ciprofloxacin. pcr and dna sequencing were used for screening and characterization of antibiotic-resis ...200617108272
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