dissemination of bla(imp-1)-carrying integron in86 among klebsiella pneumoniae isolates harboring a new trimethoprim resistance gene dfr23.the genetic context of the bla(imp-1) gene was evaluated in 9 klebsiella pneumoniae isolates recovered from 2 hospitals in são paulo, brazil. all isolates harbored a copy of in86 carrying bla(imp-1), aac(6')-31, and aada1. eight strains from the same hospital also carried another class 1 integron harboring a new trimethoprim resistance gene (dfr23) that was chromosomally embedded. in86 was likely to be in a 30-kb nontransferable plasmid and was flanked upstream by a sequence identical to one ide ...200918990526
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