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mucocutaneous leishmaniasis due to leishmania (leishmania) infantum: biochemical characterization.a vegetative mass in the right nasal cavity of a 62-year-old man from palma de mallorca, spain, was found to be due to leishmania. the organism was isolated in culture and characterized by in situ hybridization, southern blot hybridization, and isoenzyme analysis; it was thus demonstrated to be the most common enzyme variant 1 (mon 1) of leishmania (leishmania) infantum.19902267965
is leishmaniasis endemic on the island of minorca (spain)? a human visceral case after living 13 years in minorca.ecoepidemiological studies performed in minorca (balearic islands) seem to show that leishmaniasis is not endemic in this island, even in the presence of the vector. all cases of leishmaniasis in man or dog diagnosed in the island seem to come from other spanish regions. a recent case of human visceral leishmaniasis in a man who had not left minorca for 13 years calls into question this assumption or the time that leishmania may persist asymptomatic in the host.19949140474
the ibizian hound presents a predominantly cellular immune response against natural leishmania infection.veterinarians working in the balearic islands (mallorca), an endemic region of canine leishmaniosis, have reported very few cases of leishmaniosis in ibizian hounds while concurrently observing that dogs of other breeds had a high incidence of clinical canine leishmaniosis. to further investigate this observation, two populations of dogs from the balearic islands were examined for the presence of leishmania-specific cellular immunity using a delayed type hypersensitivity test (dth) to leishmanin ...200010828510
kennel dogs as sentinels of leishmania infantum, toxoplasma gondii, and neospora caninum in majorca island, spain.kennel dogs can serve as sentinels and/or reservoirs of diseases of veterinary and zoonotic interest because they have often roamed free and lived outdoors, thus being exposed to pathogens. we tested dogs from the kennel of inca (majorca/mallorca, balearic islands, spain) for evidence of infection with three protozoan parasites: leishmania infantum, toxoplasma gondii, and neospora caninum. exposure to l. infantum was found in 56.3% of 48 dogs (37.5% by western blot, 43.8% by pcr). only 30% of in ...201020689966
an investigation into alternative reservoirs of canine leishmaniasis on the endemic island of mallorca (spain).the role of wild and free-roaming domestic carnivores as a reservoir of leishmania infantum was investigated on the mediterranean island of mallorca (balearic islands, spain), an endemic area for this disease. serum, blood and/or spleen samples from 169 animals [48 dogs from a kennel, 86 wild-caught feral cats, 23 pine martens (martes martes), 10 common genets (genetta genetta) and two weasels (mustela nivalis)] were analysed. seroprevalence determined by western blotting was 38% in dogs and 16% ...201121733133
temporal trends in canine leishmaniosis in the balearic islands (spain): a veterinary questionnaire. prospective canine leishmaniosis survey and entomological studies conducted on the island of minorca, 20 years after first data were obtained.leishmaniosis is present in the mediterranean region of europe, where leishmania infantum is responsible for the disease, dogs are the main reservoir, and sand flies of the phlebotomus genus, subgenus larroussius, are proven vectors. some areas, including minorca in the balearic islands, are considered free of the disease, despite the presence of vectors. however, in the context of the current expansion of canine leishmaniosis in parts of europe, an epidemiological study using a veterinary quest ...201324055542
transfusion-transmitted leishmaniasis: a practical review.in the balearic islands, as in other areas in southern europe, there are a significant proportion of asymptomatic leishmania infantum-infected blood donors. theoretically, these donors may represent an important challenge for blood transfusion safety. however, despite an active search of multiply transfused patients, there have been, so far, no cases of transfusion-transmitted leishmaniasis (ttl) in our region. on the other hand, there is scarce evidence of the ttl in the literature. a review of ...201627001361
asymptomatic infection by leishmania infantum in blood donors from the balearic islands (spain).visceral leishmaniasis (vl) caused by leishmania infantum is a zoonotic disease endemic throughout the mediterranean basin. the existence of asymptomatic human infection entails the risk of transmission by blood transfusion.200818422844
differential ecological traits of two phlebotomus sergenti mitochondrial lineages in southwestern europe and their epidemiological implications.the introduction of leishmaniasis in a new area requires a well-established population of the sandfly vector species of the parasite. no autochthonous cases of anthroponotic cutaneous leishmaniasis have been detected in southwestern europe, and leishmania infantum is the only causative agent of leishmaniasis in this area. phlebotomus sergenti, the main vector of leishmania tropica, is commonly found in the iberian peninsula at sufficient densities to be able to act as a vector. it is characteris ...201626921209
factors influencing the presence of sand flies in majorca (balearic islands, spain) with special reference to phlebotomus pernicious, vector of leishmania infantum.although the mediterranean island of majorca is an endemic area of leishmaniosis, there is a lack of up-to-date data on its sand fly fauna, the last report dating from 1989. the aim of the present study was to provide information on the current sand fly distribution, the potential environmental factors favoring the presence of phlebotomus perniciosus and which areas are at risk of leishmaniosis.201425192589
epidemiological changes in leishmaniasis in spain according to hospitalization-based records, 1997-2011: raising awareness towards leishmaniasis in non-hiv patients.in spain, leishmania infantum is endemic, human visceral and cutaneous leishmaniasis cases occurring both in the peninsula, as well as in the balearic islands. we aimed to describe the clinical characteristics of leishmaniasis patients and the changes in the disease evolution after the introduction of antiretroviral therapy in 1997. in this descriptive study, we used spanish centralized hospital discharge database for the hospitalized leishmaniasis cases between 1997 and 2011. we included in the ...201525756785
[review of the current situation and the risk factors of leishmania infantum in spain].in spain, leishmaniasis is an endemic zoonosis present in most of the iberian peninsula and the balearic islands. the parasite detected is leishmania infantum and the main reservoir is the dog. competent vectors to transmit the parasite are sandflies, of which there are two species distributed throughout the iberian peninsula and the balearic islands. this article reviews the current situation and the behaviour of leishmaniasis in spain. it analyzes and compares information about the disease fro ...201223325131
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