Publications

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[complete genome sequencing and analyses of rabies viruses isolated from wild animals (chinese ferret-badger) in zhejiang province].based on sequencing the full-length genomes of two chinese ferret-badger, we analyzed the properties of rabies viruses genetic variation in molecular level to get information on prevalence and variation of rabies viruses in zhejiang, and to enrich the genome database of rabies viruses street strains isolated from chinese wildlife.200920193207
epidemic and maintenance of rabies in chinese ferret badgers (melogale moschata) indicated by epidemiology and the molecular signatures of rabies viruses.an epidemic of chinese ferret badger-associated human rabies was investigated in wuyuan county, jiangxi province and rabies viruses isolates from ferret badgers in different districts in jiangxi and zhejiang provinces were sequenced with their nucleotides and amino acids and aligned for epidemiological analysis. the results showed that the human rabies in wuyuan are only associated with ferret badger bites; the rabies virus can be isolated in a high percentage of ferret badgers in the epidemic a ...201323689981
characterization of the biological properties and complete genome sequence analysis of a cattle-derived rabies virus isolate from the guangxi province of southern china.in this study, a street rabies virus isolate, gxhxn, was obtained from the brain of one rabid cattle in guangxi province of southern china. to characterize the biological properties of gxhxn, we first evaluated its pathogenicity using 4-week-old adult mice. gxhxn was highly pathogenic with a short incubation period and course of disease. its ld50 of 10(-6.86)/ml is significantly higher than the ld50 of 10(-5.19)/ml of gxn119, a dog-derived rabies virus isolate. it also displayed a higher neurotr ...201425142164
[sequencing and analysis of n gene of street rabies virus isolated from different hosts in zhejiang province].to elucidate the characteristics of genetic variability and its relationship with prevalence, through sequencing and analysis of n gene among street rabies virus isolated from different hosts (homo sapiens, ferret badger, dog) in zhejiang province.201425294078
ferret badger rabies origin and its revisited importance as potential source of rabies transmission in southeast china.the frequent occurrence of ferret badger-associated human rabies cases in southeast china highlights the lack of laboratory-based surveillance and urges revisiting the potential importance of this animal in rabies transmission. to determine if the ferret badgers actually contribute to human and dog rabies cases, and the possible origin of the ferret badger-associated rabies in the region, an active rabies survey was conducted to determine the frequency of rabies infection and seroprevalence in d ...201020691095
[sequencing and analysis of complete genome of rabies viruses isolated from chinese ferret-badger and dog in zhejiang province].based on sequencing the full-length genomes of four chinese ferret-badger and dog, we analyze the properties of rabies viruses genetic variation in molecular level, get the information about rabies viruses prevalence and variation in zhejiang, and enrich the genome database of rabies viruses street strains isolated from china. rabies viruses in suckling mice were isolated, overlapped fragments were amplified by rt-pcr and full-length genomes were assembled to analyze the nucleotide and deduced p ...201020329558
[sequencing and analyses on glycoprotein gene of rabies viruses isolated in zhejiang province, china.].based on sequencing the genomes of glycoprotein (gp) gene of rabies viruses isolated in zhejiang, we analyzed the properties of rabies viruses genetic variation in molecular level, and to compare with those of other representative vaccine strains and street virus strains, get the information about rabies viruses variation.201020302704
[new animal hosts of rabies virus in mountain areas in zhejiang province].to understand the prevalence of rabies among wild animals and the animal species in rabies epidemic areas of zhejiang province.200919731524
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