major antigenic groups of rabies virus in canada determined by anti-nucleocapsid monoclonal antibodies.a total of 123 rabies virus isolates from various geographical areas in canada were characterized by a panel of 43 anti-nucleocapsid monoclonal antibodies. four major antigenic groups are found in terrestrial mammals: "canadian arctic" from ontario, quebec and the northwest territories; "south-eastern georgian bay" from ontario; "south mid-central skunk" from alberta, saskatchewan and manitoba; and "brook's, alberta skunk" from a restricted area in alberta. bat isolates can be divided into 4 maj ...19863769442
antigenic variants of rabies virus in isolates from eastern, central and northern canada.street rabies virus isolated from 51 specimens from ontario, quebec, manitoba and the northwest territories have been typed by a panel of 36 antinucleocapsid monoclonal antibodies. three main groups were found. the first group comprised those terrestrial mammals originating in ontario, quebec and the northwest territories. the second group was found in terrestrial mammals from manitoba. the third heterogenous group was made up of bats from ontario.19853893660
a molecular epidemiological study of rabies virus in central ontario and western quebec.rabies persists in ontario wildlife in two predominant species: the red fox (vulpes vulpes) and the striped skunk (mephitis mephitis). a protocol applying reverse transcription/polymerase chain reaction (rt/pcr) and restriction endonuclease analysis (rea) to the rabies virus nucleoprotein gene was previously reported by nadin-davis et al. (journal of general virology 74, 829-837, 1993) to be useful for discrimination of rabies virus variants in ontario. four main types, which showed no host spec ...19947931145
spatial and temporal dynamics of rabies virus variants in big brown bat populations across canada: footprints of an emerging zoonosis.phylogenetic analysis of a collection of rabies viruses that currently circulate in canadian big brown bats (eptesicus fuscus) identified five distinct lineages which have emerged from a common ancestor that existed over 400 years ago. four of these lineages are regionally restricted in their range while the fifth lineage, comprising two-thirds of all specimens, has emerged in recent times and exhibits a recent demographic expansion with rapid spread across the canadian range of its host. four o ...201020406385
bioeconomic modelling of raccoon rabies spread management impacts in quebec, canada.beginning in 2006, point infection control operations and aerial distribution of oral rabies vaccines along the us border were performed in quebec, canada, to control the potential spread of raccoon rabies. a benefit-cost analysis assessed the economic efficiency of this rabies control programme into the future. in this study, a mathematical simulation model was used to determine the potential spread of raccoon rabies from the 2006 index case, and incidence rates of human post-exposure prophylax ...201322709550
persistence of genetic variants of the arctic fox strain of rabies virus in southern ontario.genetic-variant analysis of rabies viruses provides the most sensitive epidemiologic tool for following the spread and persistence of these viruses in their wildlife hosts. since its introduction by a southern epizootic movement that began in the far north, the arctic fox (afx) strain of rabies virus has been enzootic in ontario for almost 50 y. prior genetic studies identified 4 principal genetic variants (ont.t1 to ont.t4) that were localized to different regions of the province; furthermore, ...200616548327
origins of the rabies viruses associated with an outbreak in newfoundland during 2002-2003.after being free of rabies of terrestrial mammals since 1988, an outbreak of rabies occurred on the island of newfoundland in december 2002 and continued into the middle of 2003. twenty-one cases, all due to the arctic fox strain of rabies virus, were reported. to explore the immediate origins of this outbreak, viruses from the newfoundland epizootic were genetically compared to two other rabies viruses recovered in mid-2002 from cartwright, a mainland coastal community near the island. while al ...200818263824
genetic tracking of the raccoon variant of rabies virus in eastern north gain insight into the incursion of the raccoon variant of rabies into the raccoon population in three canadian provinces, a collection of 192 isolates of the raccoon rabies virus (rrv) strain was acquired from across its north american range and was genetically characterized. a 516-nucleotide segment of the non-coding region between the g and l protein open reading frames, corresponding to the most variable region of the rabies virus genome, was sequenced. this analysis identified 119 differe ...201121624778
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