| probing population dynamics of trypanosoma cruzi during progression of the chronic phase in chagasic patients. | our research aimed to characterize the genetic profiles of 102 trypanosoma cruzi isolates recently obtained from 44 chronic chagasic patients from different regions of the states of minas gerais and goiás in brazil. at least two isolates were obtained from each patient at different times in order to study the parasite population dynamics during disease progression in the chronic phase. the isolates were characterized molecularly by genotyping the 3' region of the 24s alpha rrna, the mitochondria ... | 2009 | 19357212 |
| electrocardiographic characteristics in a population with high rates of seropositivity for trypanosoma cruzi infection. | this study was conducted in posse, a rural community in goiàs, brazil. persons were recruited into the study through house-to-house sampling of all houses in the sampled area. blood samples were collected for seropositivity assessments for trypanosoma cruzi and an electrocardiogram was assessed using a portable system. the results demonstrate significant differences between seropositive and seronegative persons for electrocardiographic (ecg)-derived traits. seropositive persons had substantially ... | 2007 | 17827366 |
| the epidemiologic importance of triatoma brasiliensis as a chagas disease vector in brazil: a revision of domiciliary captures during 1993-1999. | to clarify the epidemiologic importance of triatoma brasiliensis, the most important chagas disease vector in the northeastern of brazil, capture data related to this species, its distribution, capture index, and percentages of natural infection by trypanosoma cruzi were examined in 12 different brazilian states. the brazilian national health foundation collected these data from 1993 to 1999, a period during which a total of 1,591,280 triatomines (21 species) were captured in domiciles within th ... | 2003 | 12937751 |
| evaluation of the impact of chemical control measures and entomological surveillance on chagas' disease in the counties of mambaí and buritinópolis, goiás state, brazil. | epidemiological surveillance activities were implemented in 1980 in mambaí and buritinópolis counties, goiás state. twenty years later the authors evaluated the impact of these vector control measures on chagas' disease transmission, based on entomological indicators. entomological investigation was conducted using the man-hour technique and covering all domiciles. in order to study vector food sources the stomach contents of triatomines were analyzed using the modified precipitins technique. tr ... | 2001 | 11813062 |
| [general situation and perspectives of chagas disease in northeastern region, brazil]. | primary and secondary data show the importance and distribution of human chagas disease (hcd) in northeast brazil. among the 27 detected vector species, triatoma infestans, panstrongylus megistus, triatoma brasiliensis and triatoma pseudomaculata are epidemiologically important. major medical impact is attributed to t. infestans and p. megistus, the most domiciliated and vulnerable species, while the other two are native and more difficult to control. regional differences in transmission and med ... | 2000 | 11119317 |
| attitudes towards chagas' disease in an endemic brazilian community. | chagas' disease remains a major public health concern throughout much of latin america. in brazil, segments of the population experience trypanosoma cruzi infection rates as high as 65%, indicating that control programs are still needed. few data are available concerning people's health beliefs related to chagas' disease in heavily infected populations. such health beliefs may significantly impact the effectiveness of intervention schemes. the purpose of this study was to assess health beliefs r ... | 1999 | 10203442 |
| genetic epidemiology of seropositivity for trypanosoma cruzi infection in rural goias, brazil. | chagas' disease is a zoonotic disease found throughout latin america. despite control programs in many of the affected countries, infection with trypanosoma cruzi continues to be a major public health concern. in brazil alone, approximately 53 million people live in endemic areas. research with humans and with animal models indicates that there is variation in susceptibility to infection with t. cruzi. the reasons for this variation are not known although several studies have implicated genetic ... | 1997 | 9392592 |
| risk factors for trypanosoma cruzi infection among children in central brazil: a case-control study in vector control settings. | this population-based case-control study was conducted in northern goias state, central brazil, in rural settings under vector control surveillance. one hundred forty-nine children seropositive for trypanosoma cruzi antibodies, selected in a cross-sectional survey carried out in village schools, were compared with 298 seronegative classmate controls matched for age, sex, and place of residence. information on potential environmental, familiar, and social economic risk factors for t. cruzi infect ... | 1995 | 7872451 |
| [forest cycle of trypanosoma cruzi in areas of cerrado (county of formosa, state of goiás)]. | | 1981 | 6817027 |
| [domestic ecology of triatoma infestans in mambaí, goiás-brazil]. | | 1982 | 6763760 |
| [wild rodents, marsupials and triatominae captured in the municipality of mambaí--goiás. natural infection by trypanosoma cruzi]. | | 1982 | 6820182 |
| [geographical distribution and indicators entomologic of sinantropic triatomines captured in the state of goiás]. | the geographic distribution of triatomines in goiás and entomological indicators in the home environment are presented: home infestation, home triatomine density and vector infection by trypanosoma cruzi. the indicators studied were from triatomines captured inside and outside homes in 201 municipalities in the state of goiás, brazil, between 2000 and 2003. a total of 249,868 home units were investigated and 51,570 triatomines were captured, and 335 specimens were found to be infected with trypa ... | 2007 | 17568889 |
| risk factors for trypanosoma cruzi infection among blood donors in central brazil. | characteristics and possible risk factors associated with trypanosoma cruzi infection among blood donors were assessed within a routine screening programme in blood banks in an endemic area of chagas disease. 6,172 voluntary blood donors were interviewed and tested for anti-t. cruzi antibodies by haemagglutination and complement fixation tests in six blood banks in goiânia-central brazil from october 1988 to april 1989. an overall prevalence of 2.3% for t. cruzi infection was obtained, being 3.3 ... | 1992 | 1343642 |
| trypanosoma cruzi infection and electrocardiographic findings among active manual workers. a population-based study in central brazil. | in a cross sectional survey of the prevalence of trypanosoma cruzi infection among urban unskilled workers in goiânia, brazil, blood samples from 6222 manual workers from seven institutions were examined for anti-trypanosoma cruzi antibodies by immunofluorescence, elisa and haemagglutination tests. ecgs were performed and a clinical history was taken from 624 seropositive and a random sample of 529 seronegative subjects. abnormal ecgs were found in 15.1% of individuals without trypanosoma cruzi ... | 1990 | 2112518 |
| [studies on wild reservoirs and vectors of trypanosoma cruzi. xix. preliminary survey on wild triatomines in the southeastern region of the state of goiás, brasil]. | | 1967 | 4896590 |
| the effect of plastering in a house persistently infested with triatoma infestans (klug) 1934. | the replastering of a house in mambai-goias, brazil, as a measure to wall-in triatoma infestans, is briefly described. unfortunately, because the houseowner would not cooperate the roof tiles were not improved and eventually t. infestans reappeared at this site. a brief discussion follows of some aspects of house improvement in the vigilance phase of a chagas disease control programme. t. infestans appeared in the house described 51 and 258 days after the replastering. | 1992 | 1460702 |
| [the first 13 years of controlling chagas' disease in mambaí, goiás, brazil 1980-1992]. | the mambaí project was launched in 1980 for the purpose of making a longitudinal clinical-epidemiologic study of chagas' disease and of serving as a pilot program for the ministry of health of brazil. at the beginning of the project, a census was carried out, the housing units were evaluated, and clinical examination and laboratory tests were performed on the population. after a phase of massive attack with insecticides, ongoing epidemiologic surveillance was instituted in order to detect residu ... | 1994 | 8161419 |
| deep sequencing of the trypanosoma cruzi gp63 surface proteases reveals diversity and diversifying selection among chronic and congenital chagas disease patients. | chagas disease results from infection with the diploid protozoan parasite trypanosoma cruzi. t. cruzi is highly genetically diverse, and multiclonal infections in individual hosts are common, but little studied. in this study, we explore t. cruzi infection multiclonality in the context of age, sex and clinical profile among a cohort of chronic patients, as well as paired congenital cases from cochabamba, bolivia and goias, brazil using amplicon deep sequencing technology. | 2015 | 25849488 |
| [control of transmission of chagas disease in mambai-goias, brazil (1982-1984)]. | | 2006 | 3150589 |
| trends of t. cruzi infection based on data from blood bank screening. | between october 1988 and april 1989 a cross-sectional survey was carried out in six out of eight blood banks of goiánia, central brazil. subjects attending for first-time blood donation in the mornings of the study period (n = 1358) were interviewed and screened for t. cruzi infection as a part of a major study among blood donors. tests to anti-t. cruzi antibodies were performed, simultaneously, by indirect hemagglutination test (iha) and complement fixation test (cft). a subject was considered ... | 1990 | 2128905 |
| control of the transmission of chagas' disease in mambai, goias, brazil (1980-1988). | the results of entomologic surveillance conducted after chagas' disease control in mambai, goias, brazil are reported for the years 1985-1988, including a summary of results from 1980 to 1988. a progressive decrease in the incidence of triatoma infestans in houses reached zero in 1988. the threat of secondary vector colonization and the continued need for vigilance are discussed. | 1992 | 1575291 |
| [serological screening for trypanosoma cruzi among blood donors in central brazil]. | the present study compares the results of serological screening for trypanosoma cruzi infection done at blood banks with results obtained in chagas' disease studies undertaken by the reference laboratory of the federal university of goiás (ufg) and evaluates the use of the enzyme-linked immunosorbent assay (elisa) for this purpose. the study was conducted with data from six of the eight blood banks in the city of goiânia in central brazil, an urban area in which this infection is highly endemic. ... | 1992 | 1642781 |
| seroprevalence of trypanosoma cruzi infection among unskilled urban workers in central brazil. | a cross-sectional survey of the prevalence of trypanosoma cruzi infection was carried out among urban unskilled workers in an endemic area in central brazil as part of a study to assess the health impact of chagas disease and to identify risk factors for the evolution of cardiopathy. blood samples from 5425 male and female workers, aged 15-61 years, from 5 public institutions, were screened by indirect immunofluorescence, enzyme-linked immunosorbent assay and indirect haemagglutination for antib ... | 1989 | 2515628 |
| serologic screening for trypanosoma cruzi among blood donors in central brazil. | the study reported here compares results obtained by blood banks screening sera for chagasic (trypanosoma cruzi) infection with results obtained by the chagas' disease reference laboratory of the federal university of goiás in goiânia, brazil. it also evaluates results obtained using the elisa technique to screen the study sera. the survey used data from six of eight blood banks serving the city of goiânia, an urban region of central brazil where chagas' disease is highly endemic. the survey pop ... | 1992 | 1638280 |
| epidemiological vigilance with community participation in the control of the vectors of chagas' disease in goias, central brazil. | | 2011 | 3138728 |