TitleAbstractYear(sorted descending)
noninferiority of miltefosine versus meglumine antimoniate for cutaneous leishmaniasis in children.background. children have a lower response rate to antimonial drugs and higher elimination rate of antimony (sb) than adults. oral miltefosine has not been evaluated for pediatric cutaneous leishmaniasis. methods. a randomized, noninferiority clinical trial with masked evaluation was conducted at 3 locations in colombia where leishmania panamensis and leishmania guyanensis predominated. one hundred sixteen children aged 2-12 years with parasitologically confirmed cutaneous leishmaniasis were ran ...201222238470
leishmania (viannia) infection in the domestic dog in chaparral, colombia.abstract. peridomestic transmission of american cutaneous leishmaniasis is increasingly reported and dogs may be a reservoir of leishmania (viannia) in this setting. we investigated the prevalence of infection in dogs in chaparral county, colombia, the focus of an epidemic of human cutaneous leishmaniasis caused by leishmania (viannia) guyanensis. two (0.72%) of 279 dogs had lesions typical of cutaneous leishmaniasis that were biopsy positive by kinetoplast dna polymerase chain reaction-southern ...201121540374
intraspecific heterogeneity in the mini-exon gene localization of leishmania (viannia) panamensis and leishmania (viannia) guyanensis from colombia.intraspecific heterogeneity was demonstrated in the mini-exon gene localization from leishmania (viannia) panamensis and l. (viannia) guyanensis. different karyotypes were detected in human isolates circulating in endemic areas of colombia. the presence of mini-exon gene sequences on chromosomes of different sizes, ranging from 370 to 800 kb in l. (v.) panamensis and from 500 to 800 kb in l. (v.) guyanensis, was observed and was neither strain nor species specific. in some cases, hybridization w ...200011191900
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