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bacterial and fungal infections in patients with the acquired immunodeficiency syndrome.over a 14-month period, 136 episodes of bacterial and 26 episodes of fungal infection were identified from the microbiology records of 444 patients with acquired immunodeficiency syndrome (aids). the respective rates for infection were 31 of 100 admissions (bacterial) and 5 of 100 admissions (fungal). contributory factors appeared to be therapy with antineoplastic agents, ganciclovir and zidovudine, resulting in neutropenia, corticosteroid therapy, and increased use of central venous catheters. ...19902386975
the bacterial etiology and antibiotic management of septic arthritis in infants and children. 19724403468
epidemiology of pseudomonas infections in a pediatric intensive care unit. 19724628109
antimicrobial resistance of bacterial pathogens at two tertiary-care centers, in riyadh and texas.antimicrobial resistance of bacterial pathogens usually varies from one geographic location to another. during the last 20 years, outbreaks of disease caused by multiresistant bacteria have occurred with higher frequency in developing countries. we investigated the antimicrobial resistance patterns of bacteria isolated in 1992 from two tertiary-care centers, in riyadh and texas. of the 8841 strains used, 5318 were isolated from clinical specimens of patients at king faisal specialist hospital an ...19947997964
much ado about nothing: methicillin-resistant staphylococcus aureus.the pathogenic methicillin-resistant staphylococcus aureus (mrsa) has received a voluminous amount of notoriety. the four major reasons are its morbidity, mortality rate, cost of treatment, and constant appearance in intensive care units. both staphylococcus aureus and s. epidermidis (mrse) account for 82% of our gram-positive wound isolates, whereas the gram-negative account for 34% of all isolates. therefore we compared the morbidity, mortality rate, and cost factors related to mrsa-mrse and g ...19979261699
burn wound infections: current status.the burn wound represents a susceptible site for opportunistic colonization by organisms of endogenous and exogenous origin. patient factors such as age, extent of injury, and depth of burn in combination with microbial factors such as type and number of organisms, enzyme and toxin production, and motility determine the likelihood of invasive burn wound infection. burn wound infections can be classified on the basis of the causative organism, the depth of invasion, and the tissue response. diagn ...19989451928
concurrent ceftazidime due with clinical pharmacy intervention.ceftazidime use at our institution, a 580-bed county teaching hospital, has steadily increased since its addition to the formulary in 1986. in response to this increased use and because the institutional antibiogram showed increased resistance by pseudomonas aeruginosa (from 10 to 28% resistant), the p & t committee requested that a drug use evaluation (due) of ceftazidime be conducted. analysis of this retrospective pilot study showed that 87% of ceftazidime use was inappropriate. to further ev ...199410133902
clinical evaluation of coldspor, a glutaraldehyde-phenolic disinfectant.disinfecting solutions may vary in concentration and bactericidal activity with use, may have subjectively unpleasant characteristics, and may affect the appearance and physical condition of the equipment processed. we evaluated the high-level disinfectant coldspor (0.5% glutaraldehyde, 0.025% ortho-phenylphenol, and 0.005% para-tertiary amylphenol) by using it as the disinfecting agent in the processing of equipment for a large respiratory care service.199110145404
pseudomonas aeruginosa--still a frequent pathogen in patients with cancer: 11-year experience at a comprehensive cancer center. 199910476774
intracranial complications of acute mastoiditis.oral antibiotic use may have changed the incidence and microbiology of otitic intracranial complications. we reviewed cases of acute mastoiditis to document: (1) incidence of intracranial complications; (2) risk factors; and (3) identify pathologic organisms.200010767461
associations between antibiotic use and changes in susceptibility patterns of pseudomonas aeruginosa in a private, university-affiliated teaching hospital: an 8-year-experience: 1995-2002.increasing resistance in pseudomonas aeruginosa to multiple antibiotics has been observed and is posing therapeutic dilemmas. antibiotic utilization is one factor that has been associated with the emergence of antimicrobial resistance. we examined the overall and specific antimicrobial use in relation to changes in susceptibility patterns in p. aeruginosa. regression analysis was performed to explore the relationships between annual antibiotic use and the incidence of resistant p. aeruginosa. th ...200415380259
multidrug resistance associated with mexxy expression in clinical isolates of pseudomonas aeruginosa from a texas hospital.fluoroquinolones and carbapenems are important drug classes used for the treatment of pseudomonas aeruginosa infections. however, overexpression of the p. aeruginosa efflux pump, mexef-oprn, can provide dual resistance to both fluoroquinolones and carbapenems. recently, a hospital in texas encountered several p. aeruginosa isolates resistant to both of these drug classes. the purpose of this study was to determine whether the mechanism responsible for this multidrug resistance involved the overe ...200415380277
antibacterial properties of common herbal remedies of the southwest.curanderismo, widely practiced in the southwest, is an alternative medical system that has been neglected by scientific research. this project analyzed the antibiotic properties of 23 common herbal remedies used in south texas to treat wounds and infections. ethanolic tinctures and aqueous extracts of each plant were prepared and applied to blank diffusion disks. these disks were desiccated and used in kirby-bauer disk diffusion susceptibility tests on three bacteria: staphylococcus aureus, pseu ...200515894135
an integrated pharmacoeconomic approach to antimicrobial formulary decision-making.the utility of a novel interdisciplinary approach to antimicrobial formulary decision-making was studied.200616595813
blavim-2 and blavim-7 carbapenemase-producing pseudomonas aeruginosa isolates detected in a tertiary care medical center in the united states: report from the mystic program.two pseudomonas aeruginosa strains resistant to beta-lactams, fluoroquinolones, aminoglycosides, tetracyclines, and carbapenems and susceptible only to polymyxin b (mic <or= 2 microg/ml) were identified as part of the meropenem yearly susceptibility test information collection program. metallo-beta-lactamase screening tests were positive, pcr yielded products with blavim primers, and sequence analysis revealed blavim-7 and blavim-2. the isolates had distinct ribotype and pulsed-field gel elector ...200717151207
microbial keratitis pathogens and antibiotic susceptibilities: a 5-year review of cases at an urban county hospital in north texas.to review the epidemiology, risk factors, microbiologic spectrum, and outcomes of microbial keratitis and to compare cases in which a causative organism is identified to those determined to be sterile during a 5-year period at a large county hospital in north texas.200717224678
antibiotic cycling to decrease bacterial antibiotic resistance: a 5-year experience on a bone marrow transplant unit.multidrug-resistant pathogens have important effects on clinical outcomes. antibiotic cycling is one approach to control anti-microbial resistance, but few studies have examined cycling in hematology-oncology units. antibiotic cycling was implemented in january 1999 at our hematology-oncology unit, alternating piperacillin-tazobactam (pip-tazo) and cefepime in 3 months periods, until june 2004. clinical isolates were compared in post- and pre-intervention periods and with the susceptibility amon ...200717530005
infectious complications of open type iii tibial fractures among combat casualties.combat is associated with high-energy explosive injuries, often resulting in open tibial fractures complicated by nonunion and infection. we characterize the infections seen in conjunction with combat-associated type iii tibial fractures.200717638186
changing trends in acute osteomyelitis in children: impact of methicillin-resistant staphylococcus aureus infections.staphylococcus aureus remains the most common etiologic agent of acute osteomyelitis in children. recently, methicillin-resistant s. aureus (mrsa) has emerged as a major pathogen.200818580375
bacterial diversity in surgical site infections: not just aerobic cocci any more.to evaluate the microbial diversity in chronic surgical site infections (ssis).200919862869
prevalence, resistance mechanisms, and susceptibility of multidrug-resistant bloodstream isolates of pseudomonas aeruginosa.pseudomonas aeruginosa is an important pathogen commonly implicated in nosocomial infections. the occurrence of multidrug-resistant (mdr) p. aeruginosa strains is increasing worldwide and limiting our therapeutic options. the mdr phenotype can be mediated by a variety of resistance mechanisms, and the corresponding relative biofitness is not well established. we examined the prevalence, resistance mechanisms, and susceptibility of mdr p. aeruginosa isolates (resistant to > or =3 classes of antip ...201020086165
changes in the incidences of multidrug-resistant and extensively drug-resistant organisms isolated in a military medical center.multidrug-resistant (mdr) acinetobacter baumannii and pseudomonas aeruginosa have emerged as the causes of nosocomial infections in critically ill patients.201020500036
Outbreak of Pseudomonas aeruginosa surgical site infections after arthroscopic procedures: Texas, 2009.Seven organ/space surgical site infections (SSIs) that occurred after arthroscopic procedures and were due to Pseudomonas aeruginosa of indistinguishable pulsed-field gel electrophoresis (PFGE) patterns occurred at hospital X in Texas from April 22, 2009, through May 7, 2009.201122080656
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