Publications

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a bacteriophage encoding a pathogenicity island, a type-iv pilus and a phage receptor in cholera bacteria.the virulence properties of many pathogenic bacteria are due to proteins encoded by large gene clusters called pathogenicity islands, which are found in a variety of human pathogens including escherichia coli, salmonella, shigella, yersinia, helicobacter pylori, vibrio cholerae, and animal and plant pathogens such as dichelobacter nodosus and pseudomonas syringae. although the presence of pathogenicity islands is a prerequisite for many bacterial diseases, little is known about their origins or ...199910360577
comparative genomic analysis of ten streptococcus pneumoniae temperate bacteriophages.streptococcus pneumoniae is an important human pathogen that often carries temperate bacteriophages. as part of a program to characterize the genetic makeup of prophages associated with clinical strains and to assess the potential roles that they play in the biology and pathogenesis in their host, we performed comparative genomic analysis of 10 temperate pneumococcal phages. all of the genomes are organized into five major gene clusters: lysogeny, replication, packaging, morphogenesis, and lysis ...200919502408
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