Publications

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isolation of yersinia enterocolitica from some animals and meats. 19751237747
[isolation of yersinia enterocolitica from rodents in krasnodar territory]. 1979158921
comments on the ecology and epidemiology of yersinia enterocolitica in czechoslovakia.on the basis of the information disseminated by the reference laboratory in 1968, the microbiological diagnosis of yersinia enterocolitica (ye) was gradually mastered by all czechoslovak microbiological laboratories. the most frequent serotype isolated in man was ye 03. isolation predominated from cases of diarrhoea, less often from appendectomies, and only one case of septicaemia was described. usually only sporadic cases occur and outbreaks are rare. a few strains of ye 05 were found in diarrh ...1979535370
enterobacter cloacae, serratia marcescens and yersinia enterocolitica in colonies of laboratory mice, rats and rabbits: an attempt of isolation.an attempt to isolate enterobacter cloacae, serratia marcescens and yersinia enterocolitica was made in a total of 931 laboratory animals (mice, rats and rabbits) from five representative commercial breeders in this country and from our laboratory colonies. e. cloacae organisms were isolated from feces and other specimens of 15 mice and 17 rats between november 1979 and july 1980. neither s. marcescens nor y. enterocolitica was detectable in any specimen of feces, fur and skin, nasal discharge, ...19817032956
in vivo comparison of avirulent vwa- and pgm- or pstr phenotypes of yersiniae.the abilities of yersinia pestis to undergo restriction in ca2+-deficient medium with concomitant production of v and w antigens (vwa+) and to absorb exogenous pigments (pgm+) are established virulence factors. mutation of y. pestis to pgm- is known to promote resistance to pesticin (pstr) and reduced lethality by peripheral routes of injection. vwa+ pgm- isolates of y. pestis were shown in this study to retain virulence in mice when injected intravenously. although pgm- in appearance, wild-type ...19846365786
rapid identification of smooth brucella species with a monoclonal antibody.a colony blot enzyme-linked immunosorbent assay was developed for the rapid identification of smooth brucella species, i.e., brucella abortus, b. melitensis, and b. suis. bacterial colonies from plates were blotted onto nitrocellulose disks, lysed by immersion in chloroform, and reacted with bru 38, a rat monoclonal antibody with specificity for the o side chain of b. abortus. reaction with anti-rat immunoglobulin g conjugated to horseradish peroxidase and development in 4-chloro-1-naphthol resu ...19873693540
pathogenicity of yersinia enterocolitica serotype o3 biotype 3 strains.it is known that yersinia enterocolitica infection in japan is caused mainly by serotype o3 biotype 4 strains. recently, however, a number of serotype o3 strains which were classified biotype 3 and which ferment lactose and xylose, instead of sorbose, and give a negative voges-proskauer reaction have been isolated from both humans and animals. in this study, comparisons of four properties were made among isolates of y. enterocolitica serotype o3 biotype 3 from humans, pigs, dogs, cats, and rats ...19873818938
experimental animal models of yersinia infection and yersinia-induced arthritis. 19873665502
[the adhesive properties of bacteria of intestinal origin].differences between strains of nonpathogenic escherichia and lactobacilli, as well as some pathogenic bacteria of enteric origin (escherichia, shigella, campylobacter), in their capacity to adhesion to rat enteric and colonic cells have been shown in vitro. the strains under study have been found to possess more pronounced adhesiveness with respect to colonic cells, which is indicative of their higher receptive capacity in comparison with enteric cells. in the absence of normal microflora lactob ...19911801491
isolation of yersinia enterocolitica serovar o8 from free-living small rodents in japan.yersinia species were isolated from 65 of 223 free-living small mammals trapped in 10 regions on honshu island in japan. of the 65 strains isolated, 1 was yersinia enterocolitica serovar o3, 8 were y. enterocolitica o5, 6 were y. enterocolitica o8, 3 were y. enterocolitica o9, and 1 was yersinia pseudotuberculosis 4b. of the six y. enterocolitica o8 strains, five were positive for autoagglutination, ca2+ dependence, and the 45-mda virulence plasmid and showed high pathogenicity for mice.19921734061
experimental yersinia enterocolitica infection in rats: analysis of the immune response to plasmid-encoded antigens of arthritis-susceptible lewis rats and arthritis-resistant fischer rats.recently, experimentally yersinia-induced arthritis in lewis and shr rats has been described as a potential animal model for analyzing the pathomechanism of reactive arthritis (toivanen et al. 1986; hill and yu 1987). we could confirm that lewis but not fischer rats develop aseptic arthritis about 2 weeks after an intravenous inoculation of yersinia enterocolitica, serotype 0:8 (hill and yu 1987). moreover, we compared the antibody response to virulence-associated yersinia antigens (yops) of exp ...19921522826
experimental yersinia enterocolitica infection in rodents: a model for human yersiniosis.yersinia enterocolitica infection in humans causes a broad spectrum of diseases ranging from acute bowel disease to extraintestinal manifestations such as reactive arthritis, erythema nodosum and uveitis. during the last decade a fascinating part of the molecular biology of the pathogenicity of human pathogenic yersinia species has been unraveled. pathogenicity factors such as protein tyrosine phosphatase, protein kinase, thrombin- and collagen-binding factors have been identified and characteri ...19938363822
role of yada in arthritogenicity of yersinia enterocolitica serotype o:8: experimental studies with rats.outer membrane protein yada, the yersinia adhesin, is one of the plasmid-encoded virulence factors of yersiniae. to evaluate the role of yada in the pathogenesis of reactive arthritis experimentally, we used yada- strain yeo8-116, a kanamycin genblock insertion mutant derived from yersinia enterocolitica o:8 wild-type strain 8081. as control strains, a plasmid-cured derivative (8081-c) of 8081 and a yoph- mutant (8081-yoph) were used. in addition, yeo8-116, with the yada mutation transcomplement ...19947525487
role of yada-mediated collagen binding in arthritogenicity of yersinia enterocolitica serotype o:8: experimental studies with rats.outer membrane protein yada, yersinia adhesin, is one of the plasmid-encoded virulence factors of yersiniae. yada protects bacteria against host defense through several different mechanisms. one important role of yada is to mediate binding to several collagen types. our recent study revealed that a yada null mutant of yersinia enterocolitica serotype o:8 has a drastically reduced arthritogenic capacity when injected intravenously into lewis rats. to further characterize the arthritogenic role of ...19957622253
note: isolation, characterization and epidemiology of yersinia enterocolitica from humans and animals.during an 11-year period (1983 to 1994), 51 strains of yersinia enterocolitica were isolated from humans and animals. specimens were collected from a total of 3601 sources consisting of 956 patients with enteritis, 300 patients with urinary tract infection, 1564 healthy humans, 510 swine, 38 guinea-pigs, 118 rats and 115 rabbits. five strains of y. enterocolitica, bio/serogroups 2/o:9 and 4/o:3, virulence positive, were recovered from patients. forty-two variants of y. enterocolitica belonging t ...19968972095
cytoprotective effects of the 60kd heat-shock protein enhanced by heat stress in rat cardiac grafts with warm ischemic injuries. 19979123333
local expression of cytokine mrna in spleen and peyer's patches of rats is involved in resistance against infection with yersinia enterocolitica.the immune-response against infection with yersinia enterocolitica was studied in a rat model which resembles yersiniosis in humans. lewis, fischer and brown norway rats were inoculated with y. enterocolitica and the cytokine mrna expression in spleen and peyer's patches was determined. in brown norway rats the infection was mild and yersinia enterocolitica was fully cleared. in these rats the highest anti-inflammatory cytokine expression was found probably resulting in a protective host defence ...19989576066
[association of heat-shock protein and uveitis].heat-shock protein 60 derived from yersinia enterocolitica (yersinia hsp 60) and bovine retinal hsp (retina hsp 60) were previously identified by immunological cross-reaction and a high degree of common antigenicity, and a specific antibody against both proteins was detected in the sera of uveitis patients. we report here an attempt to isolate and purify retina hsp 60 and yersinia hsp 60. both retina hsp 60 and yersinia hsp 60 showed an enriched content of glycine of approximately 60 to 80%. lew ...19989720361
in situ localisation of yersinia enterocolitica by catalysed reported deposition signal amplification.the sensitive detection of pathogenic yersinia enterocolitica in paraffin embedded tissue sections by in situ hybridisation (ish).19989771443
tyrosine phosphorylation regulates manganese superoxide dismutase (mnsod) rna-binding protein activity and mnsod protein expression.all cells tested contain a cytosolic protein that binds to a defined region in the 3' untranslated region of manganese superoxide dismutase (mnsod) rna; both the mnsod rna-binding protein (mnsod-bp) and the cis element are required for efficient translation of mnsod rna [chung, d. j., wright, a. e., and clerch, l. b. (1997) biochemistry 37, 16298-16306]. this study was designed to test the hypothesis that mnsod-bp activity is regulated by phosphorylation. when cell extracts from whole rat lung o ...200111425317
protective effect of oxadin on experimental yersinia enterocolitica infection in rats.the effect of oxadin (a new bulgarian antimicrobial chemotherapeutic agent) on some parameters of non-specific immune response was investigated in a rat model of infection. after mimicking natural yersinia enterocolitica systemic infection the number and functional activity of blood leucocytes and peritoneal macrophages were compared between groups of animals treated with oxadin before and after infection. a significant immunostimulating effect of oxadin was found in both experimental groups but ...200212061259
bacteria as dna vaccine carriers for genetic immunization.genetic immunization with plasmid dna vaccines has proven to be a promising tool in conferring protective immunity in various experimental animal models of infectious diseases or tumors. recent research focuses on the use of bacteria, in particular enteroinvasive species, as effective carriers for dna vaccines. attenuated strains of shigella flexneri, salmonella spp., yersinia enterocolitica or listeria monocytogenes have shown to be attractive candidates to target dna vaccines to immunological ...200415532991
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