experimental infection with chlamydia pneumoniae in nonhuman serially examine the immunopathogenesis and histopathology of infection with chlamydia pneumoniae, we inoculated two cynomolgus monkeys in the conjunctival sac, nose, and nasopharynx with c. pneumoniae twar. after inoculation, c. pneumoniae was isolated from the inoculation sites and the rectums of both monkeys for a period of 5 weeks. after a second inoculation, c. pneumoniae was recovered from the inoculation sites and the rectums of both monkeys for 20 weeks. a third inoculation with c. pn ...19902407650
reactions of polyclonal and neutralizing anti-p54 monoclonal antibodies with an isolated, species-specific 54-kilodalton protein of chlamydia pneumoniae.a recently described 54-kda protein has been detected in six type strains and three patient isolates of chlamydia pneumoniae by immunoblotting with sera from patients positive for antibodies to c. pneumoniae by the microimmunofluorescence test. this protein was not found in either c. trachomatis e or c. psittaci z 432 as an antigen, confirming its species specificity. the 54-kda protein was isolated by continuous-elution electrophoresis and immunoglobulin g monoclonal antibodies (mabs) against t ...19979384292
advances in experimental dyslipidemia and atherosclerosis.among the models of dyslipidemia and atherosclerosis, a number of wild-type, naturally defective, and genetically modified animals (rabbits, mice, pigeons, dogs, pigs, and monkeys) have been characterized. in particular, their similarities to and differences from humans in respect to relevant biochemical, physiologic, and pathologic conditions have been evaluated. features of atherosclerotic lesions and their specific relationship to plasma lipoprotein particles have been critically reviewed and ...200111555665
identification of phylogenetic position in the chlamydiaceae family for chlamydia strains released from monkeys and humans with chlamydial pathology.based on the results of the comparative analysis concerning relatedness and evolutional difference of the 16s-23s nucleotide sequences of the middle ribosomal cluster and 23s rrna i domain, and based on identification of phylogenetic position for chlamydophila pneumoniae and chlamydia trichomatis strains released from monkeys, relatedness of the above stated isolates with similar strains released from humans and with strains having nucleotide sequences presented in the genbank electronic databas ...201020671971
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