helicobacter acinonychis: genetic and rodent infection studies of a helicobacter pylori-like gastric pathogen of cheetahs and other big cats.insights into bacterium-host interactions and genome evolution can emerge from comparisons among related species. here we studied helicobacter acinonychis (formerly h. acinonyx), a species closely related to the human gastric pathogen helicobacter pylori. two groups of strains were identified by randomly amplified polymorphic dna fingerprinting and gene sequencing: one group from six cheetahs in a u.s. zoo and two lions in a european circus, and the other group from a tiger and a lion-tiger hybr ...200414702304
who ate whom? adaptive helicobacter genomic changes that accompanied a host jump from early humans to large felines.helicobacter pylori infection of humans is so old that its population genetic structure reflects that of ancient human migrations. a closely related species, helicobacter acinonychis, is specific for large felines, including cheetahs, lions, and tigers, whereas hosts more closely related to humans harbor more distantly related helicobacter species. this observation suggests a jump between host species. but who ate whom and when did it happen? in order to resolve this question, we determined the ...200616789826
electron microscopic, genetic and protein expression analyses of helicobacter acinonychis strains from a bengal tiger.colonization by helicobacter species is commonly noted in many mammals. these infections often remain unrecognized, but can cause severe health complications or more subtle host immune perturbations. the aim of this study was to isolate and characterize putative novel helicobacter spp. from bengal tigers in thailand. morphological investigation (gram-staining and electron microscopy) and genetic studies (16srrna, 23srrna, flagellin, urease and prophage gene analyses, rapd dna fingerprinting and ...201323940723
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