retrovirus infections in non-domestic felids: serological studies and attempts to isolate a african lioness from the zoo of zurich had to be euthanized because of an inoperable tumor. the serum tested negative for feline leukemia virus (felv) p27 antigen by enzyme-linked immunosorbent assay (elisa) but was strongly positive for feline immunodeficiency virus (fiv) antibodies by elisa and western blot. when her only offspring and mate were tested for fiv, high antibody titers to fiv were also found in their serum. lymphocytes were prepared from these two lions on different occasions a ...19921337398
incidence of feline immunodeficiency virus reactive antibodies in free-ranging lions of the kruger national park and the etosha national park in southern africa detected by recombinant fiv p24 antigen.lion sera from the kruger national park (knp) dating back to 1977 and from the etosha national park (enp), obtained from 1989 to 1991, have been analysed by elisa and western blot analyses using a genetically engineered antigen representing the p24 structural protein of feline immunodeficiency virus (fiv). it was concluded that some 83% of 98 knp lion sera reacted with the p24 antigen, while none of 28 enp lion sera reacted. a few other knp felids (cheetahs and genets) gave samples that did not ...19921338477
worldwide prevalence of lentivirus infection in wild feline species: epidemiologic and phylogenetic aspects.the natural occurrence of lentiviruses closely related to feline immunodeficiency virus (fiv) in nondomestic felid species is shown here to be worldwide. cross-reactive antibodies to fiv were common in several free-ranging populations of large cats, including east african lions and cheetahs of the serengeti ecosystem and in puma (also called cougar or mountain lion) populations throughout north america. infectious puma lentivirus (plv) was isolated from several florida panthers, a severely endan ...19921382145
cryptococcosis in captive cheetah (acinonyx jubatus): two cases.cryptococcus neoformans is a yeast-like organism associated with pulmonary, meningoencephalitic, or systemic disease. this case report documents 2 cases of cryptococcosis with central nervous system involvement in captive cheetah (acinonyx jubatus). in both cases the predominant post mortal lesions were pulmonary cryptococcomas and extensive meningoencephalomyelitis. both cheetahs tested negative for feline immunodeficiency virus and feline leukaemia virus. the organism isolated in case 2 was cl ...199910855821
serosurvey of viral infections in free-ranging namibian cheetahs (acinonyx jubatus).cheetahs (acinonyx jubatus) in captivity have unusually high morbidity and mortality from infectious diseases, a trait that could be an outcome of population homogeneity or the immunomodulating effects of chronic stress. free-ranging namibian cheetahs share ancestry with captive cheetahs, but their susceptibility to infectious diseases has not been investigated. the largest remaining population of free-ranging cheetahs resides on namibian farmlands, where they share habitat with domestic dogs an ...200415137485
seroprevalence and genomic divergence of circulating strains of feline immunodeficiency virus among felidae and hyaenidae species.feline immunodeficiency virus (fiv) infects numerous wild and domestic feline species and is closely related to human immunodeficiency virus (hiv) and simian immunodeficiency virus (siv). species-specific strains of fiv have been described for domestic cat (felis catus), puma (puma concolor), lion (panthera leo), leopard (panthera pardus), and pallas' cat (otocolobus manul). here, we employ a three-antigen western blot screening (domestic cat, puma, and lion fiv antigens) and pcr analysis to sur ...200515956574
cryptococcus neoformans granuloma in the lung and spinal cord of a free-ranging cheetah (acinonyx jubatus). a clinical report and literature review.a 6-year-old, male, wild-born, free-ranging cheetah (acinonyx jubatus) was evaluated for acute onset of progressive lameness in the right hind limb. survey radiographs were unrewarding and myelography indicated an intramedullary compressive mass at the l3-l4 region. a fine needle aspirate of the lesion indicated the presence of cryptococcus organisms. necropsy confirmed the presence of granulomas (cryptococcoma) in the lung and the spinal cord (meningomyelitis) caused by cryptococcus neoformans ...200516642721
feline immunodeficiency virus (fiv) in wild pallas' cats.feline immunodeficiency virus (fiv), a feline lentivirus related to hiv, causes immune dysfunction in domestic and wild cats. the pallas' cat is the only species from asia known to harbor a species-specific strain of fiv designated fiv(oma) in natural populations. here, a 25% seroprevalence of fiv is reported from 28 wild mongolian pallas' cats sampled from 2000 to 2008. phylogenetic analysis of proviral rt-pol from eight fiv(oma) isolates from mongolia, russia, china and kazakhstan reveals a un ...201019926144
seroprevalences to viral pathogens in free-ranging and captive cheetahs (acinonyx jubatus) on namibian farmland.cheetah populations are diminishing rapidly in their natural habitat. one reason for their decline is thought to be a high susceptibility to (infectious) diseases because cheetahs in zoos suffer from high disease-induced mortality. data on the health status of free-ranging cheetahs are scarce, and little is known about their exposure and susceptibility to infectious diseases. we determined seroprevalences to nine key viruses (feline herpesvirus 1, feline calicivirus, feline parvovirus, feline co ...201019955325
serosurvey for selected viral pathogens among sympatric species of the african large predator guild in northern botswana.the recent increase in the creation of transboundary protected areas and wildlife corridors between them lends importance to information on pathogen prevalence and transmission among wildlife species that will become connected. one such initiative is the kavango zambezi transfrontier conservation area of which botswana's okavango delta constitutes a major contribution for wildlife and ecosystems. between 2008 and 2011, we collected serum samples from 14 lions ( panthera leo ), four leopards ( pa ...201727763827
solitary t-cell hepatic lymphoma with large granular lymphocyte morphology in a captive cheetah (acinonyx jubatus).a 13-yr-old male cheetah (acinonyx jubatus) presented for an acute history of lateral recumbency and anorexia. upon physical examination under general anesthesia, severe icterus was noted. a serum biochemical profile confirmed markedly elevated total bilirubin and alanine transaminase. based on ultrasound-guided liver aspirates and cytology, a presumptive diagnosis of large granular lymphocyte hepatic lymphoma was reached. abdominal and thoracic radiographs did not assist in reaching an antemort ...201526056904
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