Publications

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isogeneic versus allogeneic antiserum in the prophylaxis of experimental rabies.with a view to establishing whether rabies antiserum derived from a species genetically identical to a challenged recipient would increase or decrease its effectiveness compared with that of allogeneic antiserum, rabies immune sera produced in an inbred strain of mice and in donkeys were tested, either alone or with a course of vaccine inoculations, in mice of the same strain a few hours after intramuscular challenge with fixed cvs rabies virus. surviving mice were bled at intervals over a year ...19685302331
genetic and phylogenetic characterization of rabies virus isolates from wildlife and livestock in paraiba, brazil.thirty-four rabies virus (rv) isolates from foxes (8), insectivore bats (9), cattle (14), sheep (1), a goat (1) and a donkey (1) from paraiba state, northeastern brazil, were genetically characterized. sequences of 890 nts of nucleoprotein (n) genes of these isolates were analyzed and compared with those of other brazilian isolates characterized earlier. phylogenetic analysis revealed three genetical lineages of rv co-existing in this region. each lineage was found to be associated with particul ...200616599183
[epidemiological aspects of human and animal rabies in the urban area of bamako, mali].the district of bamako is the political and economical capital city of mali with 1,800,000 inhabitants. the goal of the present retrospective study was to determine the frequency of animal bites, human and animal rabies on the one hand and to determine the frequency and the nature of mad animals on the other hand from january 2000 to december 2003 (4 years). to achieve this goal, we have analysed registers and documents related to rabies in the department of prevention and fight against diseases ...200616983822
pathological, immunological and molecular diagnosis of rabies in clinically suspected animals of different species using four detection techniques in jordan.a total of 29 brain tissue samples (bts) were examined for rabies infection by different diagnostic techniques. none of the examined brain tissues were presented as a whole intact brain. twenty-seven brain tissue samples from various animal species - dog (13 cases), cat (one case), fox (one case), pig (one case), cow (three cases), sheep (two cases), goat (one case), camel (one case), horse (one case) and donkey (three cases) - were provided by the vaccine and sera department/al-bashir central h ...201122390575
livestock rabies outbreaks in shanxi province, china.dogs play an important role in rabies transmission throughout the world. in addition to the severe human rabies situation in china, spillover of rabies virus from dogs in recent years has caused rabies outbreaks in sheep, cattle and pigs, showing that there is an increasing threat to other domestic animals. two livestock rabies outbreaks were caused by dogs in shanxi province, china from april to october in 2015, resulting in the deaths of 60 sheep, 10 cattle and one donkey. brain samples from o ...201627422397
characterization of the biological properties and complete genome sequence analysis of a cattle-derived rabies virus isolate from the guangxi province of southern china.in this study, a street rabies virus isolate, gxhxn, was obtained from the brain of one rabid cattle in guangxi province of southern china. to characterize the biological properties of gxhxn, we first evaluated its pathogenicity using 4-week-old adult mice. gxhxn was highly pathogenic with a short incubation period and course of disease. its ld50 of 10(-6.86)/ml is significantly higher than the ld50 of 10(-5.19)/ml of gxn119, a dog-derived rabies virus isolate. it also displayed a higher neurotr ...201425142164
complete genome sequence of a rabies virus isolate from cattle in guangxi, southern china.a street rabies virus (rv) isolate, gxhxn, was obtained from brain tissue of rabid cattle in the guangxi zhuang autonomous region of china in 2009. gxhxn is the first isolate from cattle in china with its entire genome sequenced and is closely related to bj2011e from horse in beijing, wh11 from donkey in the hubei province, and isolates from dogs in the guangxi and fujian provinces, with homologies of 97.6% to 99.6%. it is more distantly related to isolates from domestic cat, pig, chinese ferret ...201323405368
[identification and sequential analysis on rabies virus isolated from a donkey].to identify and analyze the genetic characteristics of nucleoprotein (n) and glycoprotein (g) genes of rabies virus (rabv) isolated from a donkey in wuhan. n gene and g gene of the virus were compared with other representative street strains isolated around hubei areas as well as the vaccine strains used in china and abroad.201222883269
molecular characterization of the complete genome of a street rabies virus wh11 isolated from donkey in china.the complete genomic sequence of a rabies virus isolate wh11, isolated from brain tissue of a rabid donkey in china, was determined and compared with other rabies viruses. this is the first chinese street strain which was isolated from donkey and the entire length and organization of the virus was similar to that of other rabies viruses. multiple alignments of amino acid sequences of the nucleoprotein, phosphoprotein, matrix protein, glycoprotein, and large protein of wh11 with those of other ra ...201222836559
host and viral traits predict zoonotic spillover from mammals.the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ...201728636590
sequencing and sequence analysis of partial nucleoprotein (n) gene and phylogenetic analysis of rabies virus field isolates from gujarat state, india.the present study was undertaken with an aim of characterization of rabies virus (genus lyssavirus of the family rhabdoviridae under the order mononegavirales) by sequencing of partial nucleoprotein (n) gene of rabies virus and phylogenetic analysis to know the genotype and lineage of rabies virus present in gujarat state of india. a total of 32 samples (18 brain samples and 14 saliva samples) were aseptically collected from live and dead animals (viz. dog, buffalo, cow, goat, donkey and hyena) ...201729291220
epidemiological and experimental observations on the possible significance of rodents in a suburban epidemic of poliomyelitis. 194318015744
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