Publications

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porcine influenza outbreak in east anglia due to influenza a virus (h3n2) 19872832998
antigenic and genetic analyses of the hemagglutinin of influenza viruses isolated from pigs in 1993.three strains of influenza a virus (h3n2) were isolated from pigs in hokkaido, japan in 1993. the hemagglutinin (ha) antigen of the three isolates was related to that of recent h3n2 viruses of human origin. the reactivity patterns of two of the isolates (a/sw/obihiro/1/93 and a/sw/obihiro/2/93) with monoclonal antibodies to the hemagglutinin of a/bangkok/1/79 strain were similar to that of the human h3n2 strain isolated in hokkaido in 1988, while that of the other one (a/sw/obihiro/3/93) was sim ...19958720040
comparative study of the hemagglutinin and neuraminidase genes of influenza a virus h3n2, h9n2, and h5n1 subtypes using bioinformatics techniques.to investigate the genomic patterns of influenza a virus subtypes, such as h3n2, h9n2, and h5n1, we collected 1842 sequences of the hemagglutinin and neuraminidase genes from the ncbi database and parsed them into 7 categories: accession number, host species, sampling year, country, subtype, gene name, and sequence. the sequences that were isolated from the human, avian, and swine populations were extracted and stored in a mysql database for intensive analysis. the gc content and relative synony ...200717898838
swine influenza (h3n2) infection in a child and possible community transmission, canada.an influenza a virus (h3n2) of probable swine origin, designated a/canada/1158/2006, was isolated from a 7-month-old hospitalized child who lived on a communal farm in canada. the child recovered uneventfully. a serosurvey that used a hemagglutination-inhibition assay for a/canada/1158/2006 was conducted on 54 of the 90 members of the farm. seropositivity was demonstrated in the index patient, 4 of 7 household members, and 4 of 46 nonhousehold members; none had a history of hospital admission fo ...200718258037
highly conserved sequences for human neutralization epitope on hemagglutinin of influenza a viruses h3n2, h1n1 and h5n1: implication for human monoclonal antibody recognition.the epitope sequences within the hemagglutinin (ha) of influenza a virus h3n2 at amino acid residues 173-181 and 227-239 that forms anti-parallel beta-sheet structure are similarly recognized by human monoclonal antibodies (humabs), b-1 and d-1 that we recently obtained using the peripheral blood lymphocytes from two influenza-vaccinated volunteers. both humabs showed strong global neutralization of h3n2 strains. here we show the significant conservation of the beta-sheet region consisting of th ...201020152806
infection of differentiated porcine airway epithelial cells by influenza virus: differential susceptibility to infection by porcine and avian viruses.swine are important hosts for influenza a viruses playing a crucial role in the epidemiology and interspecies transmission of these viruses. respiratory epithelial cells are the primary target cells for influenza viruses.201122174804
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