Publications

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control of phage bxb1 excision by a novel recombination directionality factor.mycobacteriophage bxb1 integrates its dna at the attb site of the mycobacterium smegmatis genome using the viral attp site and a phage-encoded integrase generating the recombinant junctions attl and attr. the bxb1 integrase is a member of the serine recombinase family of site-specific recombination proteins and utilizes small (<50 base pair) substrates for recombination, promoting strand exchange without the necessity for complex higher order macromolecular architectures. to elucidate the regula ...200616719562
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