| isla vista virus: a genetically novel hantavirus of the california vole microtus californicus. | prospect hill virus (ph) was isolated from a meadow vole (microtus pennsylvanicus) in 1982, and much of its genome has been sequenced. hantaviruses of other new world microtine rodents have not been genetically characterized. we show that another microtus species (the california vole m. californicus) from the united states is host to a genetically distinct ph-like hantavirus, isla vista virus (ilv). the nucleocapsid protein of ilv differs from that of ph by 11.1% and a portion of the g2 glycopro ... | 1995 | 8847529 |
| hantavirus (bunyaviridae) infections in rodents from orange and san diego counties, california. | during a screening program to determine the extent of hantavirus activity in orange and san diego counties, california, serum samples from 2,365 rodents representing nine genera and 15 species were tested for hantavirus antibodies. a reverse transcription-polymerase chain reaction on selected seropositive rodents was used to identify the specific hantavirus. rodents positive for sin nombre virus (snv) antibodies by western blot included 86 (9.1%) of 948 deer mice (peromyscus maniculatus), four ( ... | 1999 | 9988327 |
| host and viral traits predict zoonotic spillover from mammals. | the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ... | 2017 | 28636590 |