| enterovirus 68 is associated with respiratory illness and shares biological features with both the enteroviruses and the rhinoviruses. | enterovirus (ev) 68 was originally isolated in california in 1962 from four children with respiratory illness. since that time, reports of ev68 isolation have been very uncommon. between 1989 and 2003, 12 additional ev68 clinical isolates were identified and characterized, all of which were obtained from respiratory specimens of patients with respiratory tract illnesses. no ev68 isolates from enteric specimens have been identified from these same laboratories. these recent isolates, as well as t ... | 2004 | 15302951 |
| real-time reverse transcription-pcr assay for comprehensive detection of human rhinoviruses. | human rhinoviruses (hrvs) are important contributors to respiratory disease, but their healthcare burden remains unclear, primarily because of the lack of sensitive, accurate, and convenient means of determining their causal role. to address this, we developed and clinically validated the sensitivity and specificity of a real-time reverse transcription-pcr (rt-pcr) assay targeting the viral 5' noncoding region defined by sequences obtained from all 100 currently recognized hrv prototype strains ... | 2008 | 18057136 |
| upsurge of human enterovirus 68 infections in patients with severe respiratory tract infections. | background: enterovirus 68 (ev68) belongs to species human enterovirus d. it is unique among enteroviruses because it shares properties with human rhinoviruses. after the first isolation in 1962 from four children with respiratory illness, reports of (clusters of) ev68 infections have been rare. during the autumn of 2010, we noticed an upsurge of ev68 infections in the northern part of the netherlands in patients with severe respiratory illness. objectives: to give a detailed description of the ... | 2011 | 21802981 |