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epidemic keratoconjuctivitis due to adenovirus type 19. 1976196365
conjunctivitis due to adenovirus type 19.an outbreak of unusual conjunctivitis occurred in seattle in the summer of 1974. we found evidence of adenovirus type 19 (ad19) infection in 28 of 42 (67%) referred cases from whom specimens for virus isolation and/or serology were obtained. virus was isolated from conjunctiva, throats, and/or stools, often in week 2 of illness. ad19-related cases more frequently had severe ocular pathology, transient visual impairment, and active disease for longer than a week. secondary illnesses were more fre ...1978212449
disseminated adenovirus (type 19) infection in a neonate. rapid detection of the infection by immunofluorescence.a case of fatal disseminated adenovirus infection in a neonate who suffered from severe keratoconjunctivitis and pneumonitis is reported. the diagnosis was made seven days after the onset of illness based on the detection of adenovirus antigen in the smears of the tracheal suction and conjunctival swab by immunofluorescence. viral antigen was detected in the frozen or formalin-fixed autopsy specimens of the lungs, kidneys, spleen, liver and lymph nodes. typical crystal arrangement of adenovirus ...19902166992
early region 3 of adenovirus type 19 (subgroup d) encodes an hla-binding protein distinct from that of subgroups b and c.early region 3 (e3) of human adenoviruses (ads) codes for proteins that appear to control viral interactions with the host. for example, the most abundant e3 protein, e3/19k, inhibits the transport of newly synthesized class i major histocompatibility molecules to the cell surface, thereby interfering with antigen presentation. so far, the e3 regions of ad subgroups a, b, c, and f have been characterized. we have cloned the e3a region of ad type 19a (ad19a), which belongs to the largest subgroup ...19968627757
human adenovirus type 19 infection of corneal cells induces p38 mapk-dependent interleukin-8 expression.human adenovirus type 19 (hadv-19) is a major cause of epidemic keratoconjunctivitis, the only ocular adenoviral infection associated with prolonged corneal inflammation. in this study, we investigated the role of p38 mitogen-activated protein kinase (mapk) in hadv-19 infection, with particular attention to the role of p38 mapk in the transcriptional control of interleukin-8 (il-8), a chemokine previously shown to be central to the initiation of adenovirus keratitis.200818221537
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