| african swine fever virus replication in the midgut epithelium is required for infection of ornithodoros ticks. | although the malawi lil20/1 (mal) strain of african swine fever virus (asfv) was isolated from ornithodoros sp. ticks, our attempts to experimentally infect ticks by feeding them this strain failed. ten different collections of ornithodorus porcinus porcinus ticks and one collection of o. porcinus domesticus ticks were orally exposed to a high titer of mal. at 3 weeks postinoculation (p.i.), <25% of the ticks contained detectable virus, with viral titers of <4 log(10) 50% hemadsorbing doses/ml. ... | 1999 | 10482612 |
| african swine fever virus multigene family 360 genes affect virus replication and generalization of infection in ornithodoros porcinus ticks. | recently, we reported that african swine fever virus (asfv) multigene family (mgf) 360 and 530 genes are significant swine macrophage host range determinants that function by promoting infected-cell survival. to examine the function of these genes in asfv's arthropod host, ornithodoros porcinus porcinus, an mgf360/530 gene deletion mutant (pr4delta35) was constructed from an asfv isolate of tick origin, pr4. pr4delta35 exhibited a significant growth defect in ticks. the deletion of six mgf360 an ... | 2004 | 14963141 |
| pathogenesis of african swine fever virus in ornithodoros ticks. | african swine fever virus (asfv) is the only known dna arbovirus and the sole member of the family asfarviridae. it causes a lethal, hemorrhagic disease in domestic pigs. asfv is enzootic in sub-saharan africa and is maintained in a sylvatic cycle by infecting both wild members of the suidae (e.g. warthogs) and the argasid tick ornithodoros porcinus porcinus. the pathogenesis of asfv in o. porcinus porcinus ticks is characterized by a low infectious dose, lifelong infection, efficient transmissi ... | 2001 | 11831434 |
| african swine fever virus infection in the argasid host, ornithodoros porcinus porcinus. | the pathogenesis of african swine fever virus (asfv) infection in ornithodoros porcinus porcinus was examined in nymphal ticks infected with the asfv isolate chiredzi/83/1. at times postinfection (p.i.) ranging from 6 h to 290 days, ticks or dissected tick tissues were titrated for virus and examined ultrastructurally for evidence of virus replication. the asfv infection rate in ticks was 100% in these experiments, and virus infection was not associated with a significant increase in tick mortal ... | 1998 | 9499019 |
| genetic characterization of african swine fever virus isolates from soft ticks at the wildlife/domestic interface in mozambique and identification of a novel genotype. | african swine fever virus (asfv) is one of the most threatening infectious diseases of pigs. there are not sufficient data to indicate the importance of the sylvatic cycle in the spread and maintenance of the disease locally and potentially, globally. to assess the capacity to maintain asf in the environment, we investigated the presence of soft tickreservoirs of asfv in gorongosa national park (gnp) and its surrounding villages. a total of 1,658 soft ticks were recovered from warthog burrows an ... | 2017 | 28921895 |
| african swine fever: pathogenicity and immunogenicity of two non-haemadsorbing viruses. | the virulence of 2 non-haemadsorbing african swine fever virus isolates were compared with 2 haemodsorbing viruses. while 3 of these isolates usually produced acute death in pigs, 1 non-haemadsorbing virus caused either a fatal infection with an extended course, or few or no obvious signs of infection. pigs that survived infection with the latter virus were resistant to the lethal effects of the other 3 strains as well as to a pool of 7 isolates made from ornithodorus porcinus porcinus (senus wa ... | 1979 | 551362 |