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human granulocytic ehrlichiosis in northern california: two case descriptions with genetic analysis of the ehrlichiae.we report two cases of human granulocytic ehrlichiosis (hge) that occurred in northern california in summer 1998. patients had fever, malaise, and myalgia, reported tick bites, had moderate thrombocytopenia, and had normal or slightly elevated liver enzyme activities. ehrlichial inclusions were observed in the blood of one patient, and hge-agent dna was amplified by pcr from both patients. genetically, the strains resembled horse isolates from northern california. the close spatial and temporal ...199910476747
aortic valve endocarditis in a dog due to bartonella clarridgeiae.we report the first documented case of endocarditis associated with bartonella clarridgeiae in any species. b. clarridgeiae was identified as a possible etiological agent of human cat scratch disease. infective vegetative valvular aortic endocarditis was diagnosed in a 2.5-year-old male neutered boxer. historically, the dog had been diagnosed with a systolic murmur at 16 months of age and underwent balloon valvuloplasty for severe valvular aortic stenosis. six months later, the dog was brought t ...200111574571
urban zoonoses caused by bartonella, coxiella, ehrlichia, and rickettsia species.the last half of the 20th century witnessed an increase in the occurrence and recognition of urban zoonoses caused by members of the genera bartonella, coxiella, ehrlichia, and rickettsia, all traditionally considered to be members of the family rickettsiaceae. in recent years, new human pathogens (bartonella elizabethae, bartonella henselae, and rickettsia felis) have been recognized in urban environments. other newly recognized pathogens (ehrlichia chaffeensis and ehrlichia phagocytophila in t ...200112653141
molecular evidence of tick-transmitted infections in dogs and cats in the united kingdom.pcr analysis was used to determine the prevalence of tick-transmitted infections in 120 systemically ill dogs and 60 cats recruited over a period of three months from 52 veterinary practices in the uk. the animals had not travelled outside the uk and had one or more of the following clinical criteria: acute or recurrent pyrexia, anaemia and/or thrombocytopenia, polyarthritis/muscle pain, splenomegaly/lymphadenopathy, and intraocular inflammation with systemic signs. blood samples from the animal ...200516299364
immune-mediated erythroid and megakaryocytic aplasia in a cat.a 6-month-old domestic shorthair cat was evaluated because of acute lethargy.200717397342
canine and feline vector-borne diseases in italy: current situation and perspectives.in italy, dogs and cats are at risk of becoming infected by different vector-borne pathogens, including protozoa, bacteria, and helminths. ticks, fleas, phlebotomine sand flies, and mosquitoes are recognized vectors of pathogens affecting cats and dogs, some of which (e.g., anaplasma phagocytophilum, borrelia burgdorferi, dipylidium caninum, leishmania infantum, dirofilaria immitis, and dirofilaria repens) are of zoonotic concern. recent studies have highlighted the potential of fleas as vectors ...201020145730
prevalence of selected zoonotic and vector-borne agents in dogs and cats in costa rica.to estimate the prevalence of enteric parasites and selected vector-borne agents of dogs and cats in san isidro de el general, costa rica, fecal and serum samples were collected from animals voluntarily undergoing sterilization. each fecal sample was examined for parasites by microscopic examination after fecal flotation and for giardia and cryptosporidium using an immunofluorescence assay (ifa). giardia and cryptosporidium ifa positive samples were genotyped after pcr amplification of specific ...201121846585
pcr-based survey of anaplasma phagocytophilum in portuguese ticks (acari: ixodidae).a total of two-thousand and six ticks, collected from 2002 to 2006 in areas belonging to seven districts of mainland portugal and also in madeira island, were examined by polymerase chain reaction (pcr) for the presence of anaplasma phagocytophilum. active infections were detected exclusively in ixodes species, including six questing i. ricinus nymphs from madeira island, one questing i. ventalloi nymph from setúbal district, and two i. ventalloi adults found parasitizing domestic cats in both s ...200818781886
anaplasma phagocytophilum - the most widespread tick-borne infection in animals in europe.the bacterium anaplasma phagocytophilum (formerly ehrlichia phagocytophila) may cause infection in several animal species including human. the disease in domestic ruminants is also called tick-borne fever (tbf), and has been known for at least 200 years. in europe, clinical manifestations due to a. phagocytophilum have been recorded in sheep, goat, cattle, horse, dog, cat, roe deer, reindeer and human. however, seropositive and pcr-positive mammalian have been detected in several other species. ...200717682851
prevalence of mycoplasma haemofelis, 'candidatus mycoplasma haemominutum', bartonella species, ehrlichia species, and anaplasma phagocytophilum dna in the blood of cats with anemia.hemoplasmas are known causes of anemia in some cats and some bartonella species have been associated with anemia in people and in dogs. in this retrospective study, we used polymerase chain reaction (pcr) assays to determine the prevalence rates of mycoplasma haemofelis, 'candidatus m haemominutum', a phagocytophilum, ehrlichia species, and bartonella species dna in the blood of cats with anemia and a control group of healthy cats. dna of the organisms was amplified from 22 of 89 cats with anemi ...200716846745
microscopic and clinical evidence for anaplasma (ehrlichia) phagocytophilum infection in italian cats.fifteen cats from italy with ehrlichia-like inclusion bodies in their neutrophils were studied. they were diagnosed with anaplasma (ehrlichia) phagocytophilum infection on the basis of cytological observation of morulae within 1 to 21 per cent of their neutrophils, clinical signs characteristic of ehrlichiosis and their response to doxycycline. the predominant signs of disease were anorexia, lethargy, hyperaesthesia, muscle and joint pain, lameness, neck rigidity, lymphadenomegaly, gingivitis/pe ...200515951500
anaplasma phagocytophilum: an emerging tick-borne pathogen in hungary and central eastern europe.anaplasma phagocytophilum (formerly ehrlichia phagocytophila, ehrlichia equi and anaplasma phagocytophila) is the causative agent of granulocytic ehrlichiosis (anaplasmosis) in humans, horses, sheep, cattle, dogs and cats. in the present study, 452 european sheep ticks (ixodes ricinus) collected from 100 red foxes (vulpes vulpes) in hungary were tested for the pathogen, as 112 pools each containing five or fewer ticks from one fox. six of the pools, representing ticks from six different foxes, w ...200415228721
comparison of the reservoir competence of medium-sized mammals and peromyscus leucopus for anaplasma phagocytophilum in connecticut.in the northeastern united states, anaplasma phagocytophilum, the agent of human granulocytic ehrlichiosis (hge), is transmitted by the tick vector ixodes scapularis. the white-footed mouse peromyscus leucopus is a competent reservoir for this agent, but the reservoir competence of non-peromyscus hosts of i. scapularis has not been studied. here, we report data confirming reservoir competence of medium-sized mammals for a. phagocytophilum. raccoons, virginia opossums, gray squirrels, and striped ...200212737542
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