| studies on filtrates from cultures of a psychrophilic pseudomonas sp. which inactivate nonspecific serum inhibitors for certain hemagglutinating viruses. | | 1964 | 14214378 |
| regulatory feedback loop of two phz gene clusters through 5'-untranslated regions in pseudomonas sp. m18. | phenazines are important compounds produced by pseudomonads and other bacteria. two phz gene clusters called phza1-g1 and phza2-g2, respectively, were found in the genome of pseudomonas sp. m18, an effective biocontrol agent, which is highly homologous to the opportunistic human pathogen p. aeruginosa pao1, however little is known about the correlation between the expressions of two phz gene clusters. | 2011 | 21559370 |
| emergent mechanistic diversity of enzyme-catalysed beta-diketone cleavage. | the enzymatic cleavage of c-c bonds in beta-diketones is, comparatively, a little studied biochemical process, but one that has important relevance to human metabolism, bioremediation and preparative biocatalysis. in recent studies, four types of enzymes have come to light that cleave c-c bonds in the beta-diketone functionality using different chemical mechanisms. oph [oxidized poly(vinyl alcohol) hydrolase from pseudomonas sp. strain vm15c], which cleaves nonane-4,6-dione to butyrate and penta ... | 2005 | 15934927 |
| integron carrying a novel metallo-beta-lactamase gene, blaimp-16, and a fused form of aminoglycoside-resistant gene aac(6')-30/aac(6')-ib': report from the sentry antimicrobial surveillance program. | since january 2002 pseudomonas sp. strains resistant to carbapenems and ceftazidime have been routinely screened as part of the sentry antimicrobial surveillance program for metallo-beta-lactamase production, and their resistance determinants have been analyzed. pseudomonas aeruginosa index strain 101-4704, which harbors a novel bla(imp) variant, bla(imp-16), was isolated in april 2002 from a 60-year-old man in brasilia, brazil. bla(imp-16) was found on the chromosome of the p. aeruginosa index ... | 2004 | 15561846 |
| determination of d-sorbitol in human erythrocytes by an enzymatic fluorometric method with an improved deproteinization procedure. | we developed an improved enzymatic assay of d-sorbitol in human erythrocytes by employing highly specific d-sorbitol dehydrogenase from pseudomonas sp. (ec 1.1.1.14) and replacing perchloric acid (hclo4) and potassium carbonate (k2co3), generally used for deproteinization, with sodium hydroxide (naoh) and zinc sulphate (znso4). in this assay, erythrocytes were separated from plasma by centrifugation and washed once with physiological saline. subsequently, the erythrocytes were lysed with distill ... | 2001 | 11732654 |
| [effect of norfloxacin on bacterial flora in human feces]. | norfloxacin (nflx), a synthetic oral antibacterial agent of quinolone carboxylic acid, was given orally for 5 full days at a dose of 200 mg, three times daily after each meal to healthy normal men with ages between 22 and 25 years weighing 53.0 to 84.0 kg (average 67.0 kg). the actual regimen followed was that the drug was administered twice after lunch and supper on the first day of dosing, and once after breakfast on the last day of dosing. on the 5th day before the start of dosing, on the fir ... | 1987 | 3694785 |
| human 4-hydroxyphenylpyruvate dioxygenase. primary structure and chromosomal localization of the gene. | we report the primary structure of 4-hydroxyphenylpyruvate dioxygenase [4-hydroxyphenyl-pyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating)]. the work is based on the isolation of cdna clones from human liver lambda gt11 libraries. several overlapping clones covering the coding sequence were characterized. in parallel, peptides from four different digests of the purified protein were analysed for their amino-acid sequence. these peptide sequences covered 86% of the cdna-derived amino ... | 1993 | 8504803 |
| sequence analysis and structure prediction of type ii pseudomonas sp. usm 4-55 pha synthase and an insight into its catalytic mechanism. | polyhydroxyalkanoates (pha), are biodegradable polyesters derived from many microorganisms such as the pseudomonads. these polyesters are in great demand especially in the packaging industries, the medical line as well as the paint industries. the enzyme responsible in catalyzing the formation of pha is pha synthase. due to the limited structural information, its functional properties including catalysis are lacking. therefore, this study seeks to investigate the structural properties as well as ... | 2006 | 17076907 |
| isolation and characterization of an acrylamide-degrading antarctic bacterium. | the presence of acrylamide in the environment poses a threat due to its well known neurotoxic, carcinogenic and teratogenic properties. human activities in various geographical areas are the main anthropogenic source of acrylamide pollution. in this work, an acrylamide-degrading bacterium was isolated from antarctic soil. the physiological characteristics and optimum growth conditions of the acrylamide-degrading bacteria were investigated. the isolate was tentatively identified as pseudomonas sp ... | 2009 | 20112871 |
| a model of tripeptidyl-peptidase i (cln2), a ubiquitous and highly conserved member of the sedolisin family of serine-carboxyl peptidases. | tripeptidyl-peptidase i, also known as cln2, is a member of the family of sedolisins (serine-carboxyl peptidases). in humans, defects in expression of this enzyme lead to a fatal neurodegenerative disease, classical late-infantile neuronal ceroid lipofuscinosis. similar enzymes have been found in the genomic sequences of several species, but neither systematic analyses of their distribution nor modeling of their structures have been previously attempted. | 2003 | 14609438 |
| new antitumor substances, fr901463, fr901464 and fr901465. ii. activities against experimental tumors in mice and mechanism of action. | fr901463, fr901464 and fr901465, novel antitumor substances, were isolated from the fermentation broth of pseudomonas sp. no. 2663. their antitumor activities were examined in three mouse tumor systems and one human tumor system. the three fr compounds prolonged the life of mice bearing murine ascitic tumor p388 leukemia (t/c values were 160%, 145% and 127% for fr901463, fr901464 and fr901465, respectively), and inhibited the growth of a human solid tumor, a549 lung adenocarcinoma, with differen ... | 1996 | 9031665 |
| roles of horizontal gene transfer and gene integration in evolution of 1,3-dichloropropene- and 1,2-dibromoethane-degradative pathways. | the haloalkane-degrading bacteria rhodococcus rhodochrous ncimb13064, pseudomonas pavonaceae 170, and mycobacterium sp. strain gp1 share a highly conserved haloalkane dehalogenase gene (dhaa). here, we describe the extent of the conserved dhaa segments in these three phylogenetically distinct bacteria and an analysis of their flanking sequences. the dhaa gene of the 1-chlorobutane-degrading strain ncimb13064 was found to reside within a 1-chlorobutane catabolic gene cluster, which also encodes a ... | 2000 | 10735862 |
| study on the removal of indoor vocs using biotechnology. | with the improvement of living standard and civil building innovation, large numbers of building materials and decoration are being used. the emission of gaseous organic pollutants such as formaldehyde, benzene, toluene and xylene from these materials may trigger immediate or persistent potential harm to human health. in this study, with the combination of bake-out exhaust, biological treatment was applied to deal with volatile organic compounds (vocs). four bacterial strains were isolated from ... | 2010 | 20598440 |
| [effect of cefminox on bacterial flora in human adult feces]. | cefminox (cmnx), a new cephamycin, was administered by one shot intravenous injection twice daily with a dose of 1,000 mg each time for 5 days to seven healthy male volunteers whose ages ranged from 21 to 28 years (mean: 25 years) and body weights were from 60 to 92 kg mean: 72 kg). the effect of the drug on fecal bacterial flora was investigated and the concentrations of the drug in feces were measured on 5th day before the treatment, on 0, 3rd, and 5th day (the final day of the treatment) duri ... | 1986 | 3761549 |
| bioreduction of cu(ii) by cell-free copper reductase from a copper resistant pseudomonas sp. na. | environmental copper contamination is a serious human health problem. copper reductase is produced by microorganisms to facilitate copper uptake by atpases into the cells increasing copper biosorption. this study assessed the reduction of cu(ii) by cell-free extracts of a highly copper-resistant bacterium, pseudomonas sp. strain na, isolated from vineyard soil contaminated with copper. both intact cells and cell-free extract of pseudomonas sp. strain na displayed substantial reduction of cu(ii). ... | 2010 | 21104339 |