| student research in service agencies. | | 1978 | 11661773 |
| abortion and the law: equal protection. | | 1973 | 11663435 |
| babesiosis. | a case of human babesiosis is presented. this case emphasizes the need to consider tick-borne disease in anyone who presents with prolonged and undulating fevers, chills, headache, myalgias, and arthralgias. this holds true particularly in areas endemic for tick-borne diseases, even in the absence of a history of tick bite. these symptoms, associated with signs of intravascular hemolysis, thrombocytopenia, and renal insufficiency in a patient who resides in, or with recent travel to, the northea ... | 2001 | 11165832 |
| switching doctors: predictors of voluntary disenrollment from a primary physician's practice. | our objective was to evaluate 8 interpersonal and structural features of care as predictors of patients' voluntary disenrollment from their primary care physician's practice. | 2001 | 11219560 |
| boston md--neighbors exemplify divergent views in abortion debate. | | 1976 | 11663681 |
| dr. edelin cleared by appeals court. | | 1977 | 11663717 |
| evolution of depressive symptoms in human immunodeficiency virus-infected patients entering primary care. | our purpose was to examine among hiv-infected patients a) characteristics associated with depressive symptoms at initial primary care presentation and b) factors associated with improvement in depressive symptoms. we interviewed hiv-infected patients at initial presentation and reassessed them 6 months later. at baseline and follow-up, we collected data on depressive symptoms (ces-d) and other characteristics. using multiple linear regression, we examined associations between ces-d score and bas ... | 2001 | 11225690 |
| john m. kinney international awards. looking back: a human reason for studying the effects of glutamine in patients with aids. | | 2001 | 11312061 |
| an investigation of why eligible patients do not receive haart. | treatment with highly active antiretroviral therapy (haart) decreases morbidity and mortality for persons with human immunodeficiency virus/acquired immunodeficiency syndrome (hiv/aids) and reduces costs of care. yet many patients for whom haart is indicated do not receive it. this study investigated the reasons why certain patients of a community health center with hiv/aids did not receive haart between 1997 and 1998. medical record reviews were performed to determine which patients for whom ha ... | 2001 | 11359660 |
| mbd, drug research and the schools: a conference on medical responsibility and community control, 13-14 feb 1976. | | 1976 | 11678140 |
| the treating physician as active gatekeeper in the recruitment of research subjects. | institutional review boards vary in regard to the conditions imposed on investigators concerning contacting potential subjects to participate in health-services research studies. | 2001 | 11717575 |
| blood lead levels in relation to paint and dust lead levels: the lead-safe cambridge program. | | 2001 | 11726378 |
| ige and igg antibody responses to recombinant alt a 1 as a marker of sensitization to alternaria in asthma and atopic dermatitis. | sensitization to alternaria alternata is a risk factor for the development of wheezing and asthma. alt a 1 is the major alternaria allergen causing sensitization in asthmatics. some atopic dermatitis (ad) patients have very high immunoglobulin (ig)e antibody (ab) to alternaria as analysed by pharmacia cap, however, it is not clear whether these are specific responses or whether alt a 1 is involved in disease symptoms. | 2001 | 11737041 |
| an outbreak of primary pneumonic tularemia on martha's vineyard. | in the summer of 2000, an outbreak of primary pneumonic tularemia occurred on martha's vineyard, massachusetts. the only previously reported outbreak of pneumonic tularemia in the united states also occurred on the island in 1978. | 2001 | 11757506 |
| rabies surveillance in the united states during 2000. | during 2000, 49 states, the district of columbia, and puerto rico reported 7,364 cases of rabies in nonhuman animals and 5 cases in human beings to the centers for disease control and prevention, an increase of 4.3% from 7,067 cases in nonhuman animals reported in 1999. ninety-three percent (6,855 cases) were in wild animals, whereas 6.9% (509 cases) were in domestic species (compared wth 91.5% in wild animals and 8.5% in domestic species in 1999). compared with cases reported in 1999, the numbe ... | 2001 | 11767918 |
| a mobile hiv education and testing program: bringing services to hard-to-reach populations. | few programs exist that offer a range of human immunodeficiency virus (hiv) services to multiple populations (i.e., substance abusers, individuals on probation, sex workers and their clients, court-mandated perpetrators of domestic violence) in multiple settings (i.e., courts, methadone maintenance clinics, residential and outpatient substance abuse treatment programs). the purpose of this article is to describe a model mobile hiv program, highlighting its flexibility in providing services to cl ... | 1998 | 11362065 |
| structure and seasonality of nearctic culex pipiens populations. | the abundance and structure of urban autogenous and anautogenous populations of culex pipiens mosquitoes were documented systematically in boston, ma, during three successive years. autogenous larvae become abundant mainly in enclosed sites and anautogenous larvae in sites that provide free access and egress. both populations begin to proliferate when the water temperature exceeds 15 degrees c during june. larval anautogenous mosquitoes increase in abundance 10-fold in two weeks and autogenous i ... | 2001 | 11797779 |
| sources and species of cryptosporidium oocysts in the wachusett reservoir watershed. | understanding the behavior of cryptosporidium oocysts in the environment is critical to developing improved watershed management practices for protection of the public from waterborne cryptosporidiosis. analytical methods of improved specificity and sensitivity are essential to this task. we developed a nested pcr-restriction fragment length polymorphism assay that allows detection of a single oocyst in environmental samples and differentiates the human pathogen cryptosporidium parvum from other ... | 2002 | 11823192 |
| the role of anti-glomerular basement membrane antibody in the pathogenesis of human glomerulonephritis. | | 1999 | 10361879 |
| the menopause experience: a woman's perspective. | to understand the complexities of the experience of menopause in american women from diverse ethnic and socioeconomic backgrounds. the specific aims of this phenomenologic study were to (a) examine and interpret the reality of the menopausal transition as experienced by american women and (b) identify common elements and themes that occur as a result of the complexities of this experience. | 2002 | 11843022 |
| court lets stand ruling on condoms, insurance and azt. | in three aids-related cases, the u.s. supreme court has let the decisions stand. the three cases are: curtis v. school committee of falmouth, allowing the availability of condoms in a massachusetts public school; fioretti v. massachusetts general life insurance co., invalidating a life insurance policy issued to a man with aids who used a stand-in to pass an hiv-antibody test to qualify for coverage; and barr laboratories v. burroughs wellcome co., preventing generic drug manufacturers from ente ... | 1996 | 11363161 |
| lawsuit filed. | social service providers at a boston center for haitian immigrants filed a suit in a u.s. district court against the federal government. the suit claims that auditors from the inspector general's office in the u.s. department of health and human services demanded the names of clients with aids. the auditors explained that this process, conducted to determine whether agencies are properly spending ryan white care act funds, is appropriate and routine. attorneys for the social service providers co ... | 1996 | 11363287 |
| identifying undiagnosed human immunodeficiency virus: the yield of routine, voluntary inpatient testing. | despite current recommendations for human immunodeficiency virus (hiv) counseling and testing among patients admitted to hospitals with at least a 1% prevalence of hiv infection, an estimated 300 000 people in the united states remain unaware of their hiv infection. | 2002 | 11966339 |
| prevalence of enterocytozoon bieneusi in swine: an 18-month survey at a slaughterhouse in massachusetts. | slaughterhouse pig samples were analyzed by pcr for enterocytozoon bieneusi infection. thirty-two percent were found to be positive, with rates being higher over the summer months. three isolates from pigs were identical in their ribosomal internal transcribed spacer sequence to human e. bieneusi type d, two were identical to type f (from a pig), and nine were previously unreported. the viability of these spores was demonstrated by their ability to infect gnotobiotic piglets. the presence of the ... | 2002 | 11976142 |
| state constitutions: the new battlefield for abortion rights. | | 1987 | 11649953 |
| commonwealth v. edelin. 17 dec 1976. | | 1976 | 12038352 |
| nuclear weapons: us research put to vote. | a statute banning nuclear weapons research in cambridge, massachusetts, is scheduled for a referendum vote in november 1983. if passed, the act would require the city to fine or imprison violators after the ban takes effect in october 1985, and could have an impact on work done at harvard university and the massachusetts institute of technology, as well as at the charles stark draper laboratory. lawyers for draper and the local anti-nuclear group that drafted the statute, mobilization for surv ... | 1983 | 11653480 |
| developing leadership in healthcare administration: a competency assessment tool. | despite the many graduate programs that specialize in health administration, healthcare leaders and practitioners have expressed concern about the quality of preparation of health administration graduates. the purpose of this study was to facilitate one part of an integrated approach to leadership development that spans academic and practitioner settings. the approach was to design a competency assessment tool for early careerists who have two to five years of postgraduate experience and who asp ... | 2001 | 11372221 |
| rust v. sullivan. | the federal public health service act specifies that no title x funds used for family planning services "shall be used in programs where abortion is a method of family planning." in 1988, the secretary of health and human services promulgated regulations that prohibited title x projects from abortion counseling, referral, or advocacy. various title x doctors sued, alleging violations of their first and fifth amendment rights. the supreme court found the regulations to be a permissible constru ... | 1991 | 12041295 |
| an act prohibiting experimentation on human fetuses. approved 26 jun 1974. | | 1974 | 12041354 |
| experimentation on human fetuses prohibited; medical procedures authorized; consent; approval; civil and criminal liability and proceedings; severability. | | 1976 | 12041355 |
| managing health care variability to achieve quality care. | while much has been written about variation and health care, one area that has received little attention is variation within hospitals related to the operations management--which can lead to wasted money and human resources. two boston researchers who have been studying this area say that addressing these variations--and using techniques found in other major industries across the country--could give hospitals a new tool in addressing patient safety issues, nursing shortages, cost containment, an ... | 2001 | 11400326 |
| uv doses of americans. | the uv doses of americans were never measured, but are needed for assessing the risks of uv-related health effects. we calculated these doses using a novel approach. the environmental protection agency's (epa) national human activity pattern survey (nhaps) recorded the activity profiles of 9386 americans over 24 months to assess their exposure to environmental pollutants, one of which is uv radiation. nhaps used randomized telephone interviews to get their previous day's minute-by-minute activit ... | 2001 | 11421067 |
| association of the ala54-thr polymorphism in the intestinal fatty acid-binding protein with 2-h postchallenge insulin levels in the framingham offspring study. | to investigate the association of variants of the intestinal fatty acid-binding protein gene (fabp2) with fasting and postchallenge glucose and insulin levels, hba(1c), and prevalence of type 2 diabetes in a separate sample of men and women. | 2001 | 11423496 |
| incidence, outcome, and long-term consequences of herpes simplex virus type 1 reactivation presenting as a facial rash in intubated adult burn patients treated with acyclovir. | increased mortality, extensive visceral involvement, and necrotizing tracheobronchitis associated with herpes viruses have been reported after burns. it is unclear whether herpes presenting as a facial rash results in outcome changes after burns. | 2002 | 12131395 |
| just-in-time delivery comes to knowledge management. | like all primary care physicians, dr. bob goldszer must stay on top of approximately 10,000 different diseases and syndromes, 3,000 medications, 1,100 laboratory tests, and many of the 400,000 articles added each year to the biomedical literature. that's no easy task. and it is, quite literally, a matter of life and death. the institute of medicine's 1999 report, to err is human, suggests that more than a million injuries, and 90,000 deaths are attributable to medical errors annually. something ... | 2002 | 12140850 |
| management of patients with chronic renal insufficiency in the northeastern united states. | comorbid conditions that develop during chronic renal insufficiency (cri) contribute to the high morbidity and mortality among patients with end-stage renal disease (esrd). thus, appropriate management during cri may lead to improved esrd outcomes. a retrospective cohort study was performed to describe the management of patients with cri. a total of 602 patients with cri (creatinine > or =1.5 mg/dl for women and > or =2.0 mg/dl for men) were seen between october 1994 and september 1998 at five n ... | 2001 | 11423579 |
| robley evans and what physics can do for medicine. | when asked, in 1936 by j. howard means, chief of medicine at massachusetts general hospital, whether radioiodine could be produced for thyroid studies, karl t. compton, president of the massachusetts institute of technology, referred the question to robley evans of the physics department. in response, evans formed a team from the fields of physics and medicine that produced 128i for animal studies and, subsequently on a cyclotron dedicated to medical purposes, 130i for human uptake measurements ... | 2001 | 11471483 |
| an instrument for determining the amount of nih support for clinical investigations at one academic health center. | although interest in supporting clinical investigators is increasing, information regarding the quantity, spectrum, and specific types of clinical research performed in academic health centers (ahcs) is generally not available. the authors report on an instrument to quantify the national institutes of health (nih)-funded component of clinical research at one institution. | 2002 | 12176698 |
| the new york times ad. | feminization of patriarchal institutions is necessary in order to eliminate the exclusivity and mutuality of hierarchical, gender, class, and race stratification. the aim of this paper is to explain the history and activities surrounding the new york times ad on sunday, october 7, 1984 (the catholic statement on pluralism and abortion signed by barbara ferraro and patricia hussey of the sisters of note dame de namur, rose dominic trapasso of the maryknoll sisters, and 67 other signers). the si ... | 1993 | 12178920 |
| child study at clark university: 1894-1904. | | 1990 | 11607967 |
| the genetic revolution at work: legislative efforts to protect employees. | | 2002 | 12197465 |
| fetal research: the case history of a massachusetts law. | | 1975 | 11643258 |
| fetal research (ii): the nature of a massachusetts law. | | 1975 | 11643261 |
| antiretroviral drug resistance mutations in antiretroviral-naive prisoners. | we assessed the incidence of antiretroviral drug resistance in a cohort of 25 antiretroviral-naive, human immunodeficiency virus-positive inmates in massachusetts. silent mutations, unexpected mutations at resistant sites, and resistance mutations were recorded. among these inmates, we found a prevalence of drug resistance mutations that was equivalent to the prevalence previously found in nonprison populations in the same state. | 2002 | 12228827 |
| fetal research (iii): the impact of a massachusetts law. | | 1975 | 11643265 |
| family planning services and population research act. | the senate human resources subcommittee under the chairmanship of senator alan cranston has completed its work on the family planning services and population research amendments of 1973 (s. 1708) and has referred the bill to the senate labor and public welfare committee. right-to-life activists are zeroing in on committee members in hopes of amending the bill to prohibit federal funds for sterilization and continued research on abortifacient drugs. if such provisions were to be approved, it w ... | 1973 | 12276914 |
| planned parenthood federation of america v. bowen, 25 february 1988. | the plaintiffs were family planning (fp) services and physicians who sought a preliminary injunction against enforcement of regulations promulgated by the secretary of health and human services of the us. the regulations prohibited counseling and referral for abortion services by fp services that receive funds under title x of the public health services act. the court held that the regulations exceeded the secretary's authority, since nothing in title x or legislative history relating to its e ... | 1988 | 12289568 |
| akron center for reproductive health v. slaby, 12 august 1988. | in a challenge to the constitutionality of parental notification provisions of ohio's abortion statute, the appeals court held certain provisions of the statute unconstitutional. this ruling was reversed by the us supreme court in 1990. in minnesota in 1988, the appeals court held constitutional parental notification provisions requiring that a minor give both parents 48 hours' notice before undergoing an abortion unless a judicial waiver is obtained. this ruling was upheld by the us supreme ... | 1988 | 12289574 |
| experiment perilous: forty-five years as a participant observer of patient-oriented clinical research. | | 1996 | 11644830 |
| legal trends in bioethics. | | 1996 | 11644885 |
| massachusetts high court supports use of civil rights law to bar blockades. | in a 4-3 opinion issued on april 11, the supreme judicial court of the commonwealth of massachusetts affirmed a lower court order preventing anti-choice activists from blocking access to a facility providing abortion counseling or services. granted under the massachusetts civil rights act, the injunction also prohibits using force against anyone entering, leaving, or working at such a location (see rfn ii/22). several health care providers and pro-choice organizations obtained a preliminary inj ... | 1994 | 12318701 |
| epidemiologic transition in the united states: the health factor in population change. | the general theory of epidemiologic transition is explained. the theory hypothesizes that long-term changes in health and disease patterns in any society are related to the demographic and social conditions in that country. mortality is considered to be the major factor in population change. the theory is illustrated by a detailed consideration of birth and death trends in the u.s. mortality decline began in the u.s. in the middle of the nineteenth century. associated with this decline was ... | 1977 | 12335110 |
| commonwealth of massachusetts v. bowen. | the u.s. department of health and human services (dhhs) promulgated regulations on 2 feb 1988 prohibiting the use of any federal funds by health clinics that engage in abortion counseling and referral or in abortion lobbying and advocacy, even if the clinics make use of nonfederal funds for these activities. the u.s. district court, d. massachusetts, found that the regulations violated both constitutional rights, under the first amendment in particular, and congressional intent. the court issu ... | 1988 | 11648376 |
| commonwealth v. cass. | the massachusetts supreme judicial court decided the question of whether a viable fetus is a "person" for purposes of the vehicular homicide statute in massachusetts. although the common law rule in every american jurisdiction that has considered the question, including massachusetts, has been that the destruction of the fetus in utero is not homicide, the supreme judicial court ruled to the contrary. confident in the ability of medical science to provide competent proof as to whether the cond ... | 1984 | 12041184 |
| care and protection of beth. | the supreme judicial court of massachusetts upheld the lower court's "do not resuscitate" (dnr) order regarding a five-year-old child who had been in an irreversible coma since infancy. although dnr orders generally do not require judicial review, the fact that both parents were minors and the mother and child were in the custody of the department of social services necessitated judicial involvement. using the doctrine of substituted judgment, the court determined that the incompetent child woul ... | 1992 | 12041221 |
| history of pediatric liver transplantation. where are we coming from? where do we stand? | the history of pediatric liver transplantation cannot be dissociated from one man, thomas e. starzl, whose pioneer efforts contributed more than anyone else to what has become a routinely successful clinical procedure. during the pre-cyclosporine era, the pediatric experience was confined nearly exclusively in denver: first attempt in 1963, first success with survival beyond one year in 1967, cumulative experience with 84 pediatric cases in the pre-cyclosporine era (1967-1979) with a 2-year pati ... | 2002 | 12390423 |
| from comstockery through population control: the inevitability of balancing. | | 1974 | 11663527 |
| industry-related outbreak of human anthrax, massachusetts, 1868. | | 2002 | 12396936 |
| use of physical, chemical, and biological indices to assess impacts of contaminants and physical habitat alteration in urban streams. | human activities in urban areas can lead to both chemical pollution and physical alteration of stream habitats. the evaluation of ecological impacts on urban streams can be problematic where both types of degradation occur. effects of contaminants, for example, may be masked if stream channelization, loss of riparian vegetation, or other physical stressors exert comparable or larger influences. in the aberjona watershed (near boston, ma, usa), we used physical, chemical, and biological indices t ... | 2002 | 12069298 |
| the effect of education on backpack wearing and posture in a middle school population. | the effect of education on proper wearing of a backpack was studied to determine whether or not a middle school population would improve posture during load carriage by maintaining a more natural posture and to determine if schoolchildren would comply with proper backpack wearing. | 2002 | 12441569 |
| efficacy of body mechanics education on posture while computing in middle school children. | the purposes of this pilot study were to examine the working position of middle school children during their media/technology class, test student's knowledge of healthy computing habits, and evaluate the efficacy of two educational interventions compared to a control group. | 2002 | 12441570 |
| fetal research iv: the living fetus and the law--the state's role. | | 1975 | 11663566 |
| foetal research aborted in united states. | | 1974 | 11664375 |
| rabies surveillance in the united states during 2001. | during 2001, 49 states and puerto rico reported 7,437 cases of rabies in nonhuman animals and 1 case in a human being to the centers for disease control and prevention, an increase of < 1% from 7,364 cases in nonhuman animals and 5 human cases reported in 2000. more than 93% (6,939 cases) were in wild animals, whereas 6.7% (497 cases) were in domestic species (compared with 93.0% in wild animals and 6.9% in domestic species in 2000). the number of cases reported in 2001 increased among bats, cat ... | 2002 | 12494966 |
| ethical problems in fetal research. | | 1975 | 11664449 |
| psychosurgery in massachusetts: a task force report. | | 1975 | 11664587 |
| adult blood lead epidemiology and surveillance--united states, 1998-2001. | elevated blood lead levels (blls) in adults can damage the cardiovascular, central nervous, reproductive, hematologic, and renal systems. the majority of cases are workplace-related. u.s. department of health and human services recommends that blls among all adults be reduced to < 25 microg/dl. the highest bll acceptable by standards of the u.s. occupational safety and health administration is 40 microg/dl. the mean bll of adults in the united states is < 3 microg/dl. | 2002 | 12528812 |
| high prevalence of viable toxoplasma gondii infection in market weight pigs from a farm in massachusetts. | the ingestion of uncooked infected meat is considered important in the epidemiology of toxoplasma gondii infection in humans and little is known of the prevalence of viable t. gondii in meat used for human consumption in the united states. in the present study, viable t. gondii was isolated from 51 out of 55 pigs destined for human consumption. hearts and tongues (500 g) from fifty-five 6-mo-old pigs from a farm in massachusetts were bioassayed for t. gondii by feeding them to t. gondii-free cat ... | 2002 | 12539744 |
| human milk lipids bind shiga toxin. | hemolytic uremic syndrome, a serious complication of shiga toxin-associated diarrhea, is rare before 6 months of age. immunologic and nonimmunologic factors present in human milk may partially explain this observation. in prior studies, we have demonstrated that human milk contains gb3, the receptor for the b subunit of shiga toxin, and also contains secretory iga (siga) against the toxin. we therefore sought to determine the relative importance of milk glycolipid and toxin-specific siga in toxi ... | 2001 | 11787699 |
| effects on breastfeeding of changes in maternity length-of-stay policy in a large health maintenance organization. | the purpose of this study was to evaluate the effects on breastfeeding rates of a private-sector early discharge program and a subsequent government mandate guaranteeing 48 hours of hospital coverage. | 2003 | 12612230 |
| us: court refuses to order disclosure of hiv status to police. | in february 2001, massachusetts' highest court ruled that a man whose blood was splattered on police officers during his arrest is protected under that state's law from having to reveal his hiv status. | 2001 | 11837039 |
| use of complementary and alternative therapies by patients with human immunodeficiency virus disease in the era of highly active antiretroviral therapy. | complementary and alternative medical therapies (cam) are popular with patients who are human immunodeficiency virus (hiv) seropositive, despite effective drug treatments, potential drug interactions, and overlapping toxicities. | 2003 | 12676036 |
| implementation of a point-of-care satellite laboratory in the emergency department of an academic medical center. impact on test turnaround time and patient emergency department length of stay. | emergency department (ed) overcrowding has reached crisis proportions in the united states. many hospitals are seeking to identify process reengineering efforts to reduce crowding and ed patient length of stay (los). | 2003 | 12683874 |
| using gis and historical records to reconstruct residential exposure to large-scale pesticide application. | investigation of pesticide impacts on human health depends on good measures of exposure. historical exposure data are needed to study health outcomes, such as cancer, that involve long latency periods, and other outcomes that are a function of the timing of exposure. environmental or biological samples collected at the time of epidemiologic study may not represent historical exposure levels. to study the relationship between residential exposure to pesticides and breast cancer on cape cod, massa ... | 2002 | 11859434 |
| particulate matter and polycyclic aromatic hydrocarbon concentrations in indoor and outdoor microenvironments in boston, massachusetts. | estimating personal exposures to air pollution is a crucial component in identifying high-risk populations and determining efficient control strategies. because of the difficulty of comprehensively measuring personal exposure, data on air pollution patterns in homogenous microenvironments linked with activity data are often used as surrogates. in this study, we focus on strengthening the available information about nonresidential microenvironmental exposures to particulate matter and other combu ... | 2002 | 11965527 |
| boston happens program: hiv-positive, homeless, and at-risk youth can access care through youth-oriented hiv services. | the boston happens program is a collaborative network of care consisting of multiservice outreach agencies; community health centers; and hospitals for hiv-positive, homeless, and hard-to-reach youth. in four years of data collection, the program served more than 2,000 youth, including 54 hiv-positive youth. the youth were 19.9 +/- 2.9 years old; 64 percent female; 45 percent youth of color; 11 percent gay/lesbian, bisexual, or undecided; and 13 percent homeless or runaway. homeless youth were m ... | 2003 | 12748922 |
| implementing the precautionary principle. | the precautionary principle can be found in international treaties that protect human health and the environment from a variety of pollutants and perturbations. one of the earliest forms of the precautionary principle was used in the 1980s in europe to protect the north sea. in 1992, the rio declaration specifically included the precautionary principle in calling on nations to protect the environment. the us articulation that best embodies this approach to environment and human health protection ... | 2002 | 12013543 |
| case records of the massachusetts general hospital. weekly clinicopathological exercises. case 20-2002. a 37-year-old man with fever, hepatosplenomegaly, and a cutaneous foot lesion after a trip to africa. | | 2002 | 12087144 |
| evidence for heritability of abdominal aortic calcific deposits in the framingham heart study. | atherosclerosis is a systemic disease that underlies clinical cardiovascular disease. the radiographic finding of abdominal aortic calcific deposits is an indicator of the presence of aortic atherosclerosis and an independent predictor of cardiovascular disease events. little is known about the heritability of aortic calcification. | 2002 | 12119250 |
| information architect. jeff blair's passion for the industry promotes healthcare standards and the electronic health record. | | 2002 | 12827789 |
| quantification of respirable, thoracic, and inhalable quartz exposures by ft-ir in personal impactor samples from construction sites. | the classification of quartz as a group i human carcinogen by the international agency for research on cancer (iarc) highlights the need to develop a method to assess quartz exposures in the thoracic and inhalable particle size fractions to supplement the current method for the respirable size fraction. heavy and highway construction operations can produce high respirable quartz exposures, but inhalable and thoracic exposures have not previously been well characterized. these larger particle siz ... | 2002 | 12166893 |
| mental retardation research center at boston children's hospital/harvard medical school. introductory overview. | the mrrc at children's hospital/harvard medical school is focused on research in genetics and neuroscience. both clinical and basic science approaches are abundant. major interdisciplinary programs, particularly in the areas of neonatal brain injury, human cerebral cortical malformations, and human neuromuscular disorders, interdigitate basic and clinical research in cohesive research programs. the core research support facilities serve as the nidus for this large research effort, encompassing 6 ... | 2002 | 12175871 |
| enzootic transmission of anaplasma bovis in nantucket cottontail rabbits. | serological studies of cottontail rabbits sampled from nantucket island, mass., have suggested exposure to at least two ehrlichiae. the agent of human granulocytic ehrlichiosis (anaplasma phagocytophilum) is intensely enzootic in rabbits there, but the identity of the other ehrlichial infection remains undescribed. we sampled rabbits over five transmission seasons and tested their blood and tissues for evidence of infection using pcr targeting an ehrlichia genus-wide 16s rdna target. sequence an ... | 2003 | 12904385 |
| mortality of common loons in new england, 1987 to 2000. | diagnostic findings are presented on 522 common loons (gavia immer) found dead or moribund in new england (connecticut, maine, massachusetts, new hampshire, rhode island, and vermont, usa) between 1987 and 2000. common loon numbers and range in new england have decreased from historic levels over the last century due to a number of proposed factors. goals of this study were to identify and categorize causes of mortality and quantify natural versus anthropogenic causes. the majority of identifiab ... | 2003 | 12910757 |
| us refuses to issue entry visas to people with hiv / aids. | the us government, ignoring the almost unanimous recommendation of medical and public health experts throughout the world, continues to ban both immigration and travel by people with hiv. following recommendations from the us centers for disease control and prevention, the us department of health and human services indicated its intention to reduce the list of dangerous and contagious diseases for excluding entry to the us to include only active tuberculosis. that decision would have removed h ... | 1991 | 12179700 |
| genome screen for quantitative trait loci contributing to normal variation in bone mineral density: the framingham study. | a genome-wide scan was performed in a randomly ascertained set of 330 extended families from the population-based framingham study to identify chromosomal regions possibly linked to bone mineral density (bmd). a set of 401 microsatellite markers was typed at a 10-centimorgan (cm) average density throughout the genome. bmd was measured at the femoral neck, trochanter, ward's area, and lumbar spine in 1557 participants of both framingham cohorts. bmds were adjusted for age, body mass index (bmi), ... | 2002 | 12211443 |
| case records of the massachusetts general hospital. weekly clinicopathological exercises. case 26-2003. a 50-year-old colombian man with fever and seizures. | | 2003 | 12930932 |
| cost-effectiveness of serotesting compared with universal immunization for varicella in refugee children from six geographic regions. | it is unknown whether it is more cost-effective to test for varicella antibody or to immunize without testing in immigrant populations. the reliability of history of varicella disease is also unclear. | 2003 | 12946297 |
| barriers, facilitators, and access for wheelchair users: substantive and methodologic lessons from a pilot study of environmental effects. | we undertook a month-long intensive pilot study of a sample of adult wheelchair-users in boston, massachusetts and durham, north carolina, usa. the study had four objectives; to: (1) measure experiences of reaching and failing to reach specific destinations; (2) measure encounters with environmental facilitators and barriers, including both those overcome and not overcome; (3) determine the frequencies of destinations, facilitators, and barriers, and (4) test for consistency between daily report ... | 2002 | 12231020 |
| gregory pincus, father of the pill. | this paper presents the profiles of gregory pincus, popularly known as the "father of the pill". pincus was considered a brilliant scientist who developed an oral contraceptive in 1950. he had already achieved in vitro fertilization of rabbit eggs, foreshadowing later successes in assisted human reproduction that have enabled tens of thousands of couples to overcome infertility. his discovery, however, generated controversy, which cost him tenure at harvard, prompting his move to clark universi ... | 2000 | 12296230 |
| contributions of a clinical genetics laboratory to the diagnosis and treatment of disease in childhood. | | 1963 | 14045779 |
| five new viral exanthems. | | 1964 | 14180572 |
| hybridon and aegera collaborate to develop antisense drug. | | 2002 | 12382515 |
| a population-based study of ashkenazi jewish women's attitudes toward genetic discrimination and brca1/2 testing. | the human genome project continues to produce an increasing number of genetic susceptibility tests. some of these genetic tests target social or ethnic groups who are at increased risk of developing a disease. the ashkenazi jewish community is one ethnic group that is an ongoing subject of genetic investigation. we assessed the attitudes of a population-based sample of ashkenazi jewish women toward breast-ovarian cancer susceptibility testing (brca 1/2). in particular, we assessed concerns about ... | 2002 | 12394347 |
| the association between children's computer use and musculoskeletal discomfort. | as american children spend more time working at computers, they may be putting themselves at risk for musculoskeletal disorders and other conditions that can result from overuse. there is little research that describes the home computer use of american middle school children or that describes the prevalence of musculoskeletal discomfort in this population. this study provides a general description of the computer set-up and home use of 152 6th grade children and looks at the association between ... | 2002 | 12441562 |
| initiation of services in the boston happens program: human immunodeficiency virus-positive, homeless, and at-risk youth can access services. | this study evaluates the factors associated with initiation of services in the boston happens program, which is a collaborative network of care consisting of multiservice outreach agencies, community health centers and hospitals, for human immunodeficiency virus (hiv)-positive and hard to reach youth who are 12-24 years old. the program served 2116 youth who were 19.8 +/- 2.9 years old; 64% female; 45% youth of color; 16% gay/lesbian, bisexual, or undecided; and 10% homeless or runaway. at first ... | 2002 | 12442735 |
| dinoflagellate cyst records and human disturbance in two neighboring estuaries, new bedford harbor and apponagansett bay, massachusetts (usa). | the dinoflagellate cyst records in sediments from new bedford harbor and apponagansett bay demonstrate sensitivity to environmental change caused by human activity in the watersheds over the last 500 years. changes in the species richness, as well as absolute and relative abundance of dinoflagellate cyst taxa reflect recent periods of development around the estuaries. cyst taxa sensitive to these changes include dubridinium spp., polykrikos schwartzii, lingulodinium machaerophorum, operculodiniu ... | 2002 | 12449331 |
| bernard brouwer's lecture tours in the united states (1926 and 1933). | bernard brouwer (1881-1949), the first ordinary professor of neurology in the netherlands and a man of prominent stature among continental neurologists, was invited to read lectures at several university clinics in the united states in 1926 and 1933. in this article, we describe brouwer's impressions from these tours to obtain a view of us neurology in the 1920s and 1930s compared with the state of dutch neurology. we studied brouwer's reports of the lecture tours and pertinent materials obtaine ... | 2003 | 14568822 |
| antiretroviral drug resistance in human immunodeficiency virus-infected source patients for occupational exposures to healthcare workers. | to assess the prevalence of hiv antiretroviral resistance among source patients for occupational hiv exposures. | 2003 | 14587931 |