| tissue tropism of swine influenza viruses and reassortants in ex vivo cultures of the human respiratory tract and conjunctiva. | the 2009 pandemic influenza h1n1 (h1n1pdm) virus was generated by reassortment of swine influenza viruses of different lineages. this was the first influenza pandemic to emerge in over 4 decades and the first to occur after the realization that influenza pandemics arise from influenza viruses of animals. in order to understand the biological determinants of pandemic emergence, it is relevant to compare the tropism of different lineages of swine influenza viruses and reassortants derived from the ... | 2011 | 21880750 |
| cardiac injury in patients with pandemic 2009 influenza a (h1n1) infection. | in march 2009, the novel 2009 influenza a (h1n1) was first reported in the southwest of mexico, and rapidly spread worldwide. we investigated the clinical features of cardiovascular involvement of patients infected with the 2009 influenza a (h1n1) virus in china. | 2011 | 21894797 |
| host and viral traits predict zoonotic spillover from mammals. | the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ... | 2017 | 28636590 |